Charalampos Tzoulis
@chtzoulis.bsky.social
Professor of Neurology and Neurogenetics | Parkinson's disease Researcher | Clinical Trialist | Humanist & Science Advocate
Our latest work provides insights into the cell-specific gene expression landscape of Parkinson's disease (PD), PD caused by LRRK2 mutations, and multiple system atrophy (MSA). We also explore signatures associated with α-syn pathology: url:https://academic.oup.com/brain/article/148/5/1588/7901271
May 15, 2025 at 2:46 PM
Our latest work provides insights into the cell-specific gene expression landscape of Parkinson's disease (PD), PD caused by LRRK2 mutations, and multiple system atrophy (MSA). We also explore signatures associated with α-syn pathology: url:https://academic.oup.com/brain/article/148/5/1588/7901271
Fresh from our lab - Analyses of muscle biopsies from persons with Parkinson's disease indicate the existence of a subgroup with impaired mitochodrial function. Another step towards biological stratification of PD: www.nature.com/articles/s43...
Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson’s disease - Communications Medicine
Kverneng et al. assess the mitochondrial respiratory chain in skeletal muscle from persons with Parkinson’s disease. Their findings suggest the existence of a subpopulation with complex I deficiency a...
www.nature.com
April 30, 2025 at 8:07 AM
Fresh from our lab - Analyses of muscle biopsies from persons with Parkinson's disease indicate the existence of a subgroup with impaired mitochodrial function. Another step towards biological stratification of PD: www.nature.com/articles/s43...
Check out our latest opinion paper on NAD augmentation as a disease-modifying strategy for neurodegeneration in Trends in Endocrinology & Metabolism www.cell.com/trends/endoc...
NAD augmentation as a disease-modifying strategy for neurodegeneration
Neurodegenerative diseases (NDDs) pose a significant and rapidly growing global health
challenge, but there are no effective therapies to delay or halt progression. In recent
years augmentation of nic...
www.cell.com
April 26, 2025 at 3:25 PM
Check out our latest opinion paper on NAD augmentation as a disease-modifying strategy for neurodegeneration in Trends in Endocrinology & Metabolism www.cell.com/trends/endoc...