Chris Sundling
@chrissundling.bsky.social
Research group leader @Karolinskainst, working with immunoregulation in infectious diseases. B cells have a special place in my heart
I realise the link did not work. Here is the correct link: journals.asm.org/doi/10.1128/...
A multiplex Mtb-specific FluoroSpot assay measuring IFNγ, IL-2, and TNF-secreting cells can improve accuracy and differentiation across the tuberculosis spectrum | Journal of Clinical Microbiology
Accurate diagnosis of Mycobacterium tuberculosis (Mtb) infection remains a cornerstone in tuberculosis (TB) control. Current interferon-gamma
release assays (IGRAs) lack the ability to distinguish bet...
journals.asm.org
October 30, 2025 at 7:10 AM
I realise the link did not work. Here is the correct link: journals.asm.org/doi/10.1128/...
Great collaborative team of lab and clincal researchers performing this study with lots of effort from excellent medical students and lab members building the cohort and performing experiments.
@ki.se @gunkal.bsky.social #Tuberculosis #Immunology @pucallpa.bsky.social @asm.org
@ki.se @gunkal.bsky.social #Tuberculosis #Immunology @pucallpa.bsky.social @asm.org
October 29, 2025 at 1:45 PM
Great collaborative team of lab and clincal researchers performing this study with lots of effort from excellent medical students and lab members building the cohort and performing experiments.
@ki.se @gunkal.bsky.social #Tuberculosis #Immunology @pucallpa.bsky.social @asm.org
@ki.se @gunkal.bsky.social #Tuberculosis #Immunology @pucallpa.bsky.social @asm.org
More specifically, very recent infection displayed reduced IFNg production and more geared towards IL2 and TNF while TB disease was associated with dual production of IFNg and TNF.
October 29, 2025 at 1:45 PM
More specifically, very recent infection displayed reduced IFNg production and more geared towards IL2 and TNF while TB disease was associated with dual production of IFNg and TNF.
Key take homes: 1) measuring polyfunctional cells can increase assay specificity, 2) infection stage is associated with specific cytokine patterns
October 29, 2025 at 1:45 PM
Key take homes: 1) measuring polyfunctional cells can increase assay specificity, 2) infection stage is associated with specific cytokine patterns