Chris Weston
@chris-west0n.bsky.social
Biochemist, liver poker, immune cell tinkerer, fibroblast fiddler, macrophage meddler. University of Birmingham.
Reposted by Chris Weston
This is fucking terrifying. In one meeting acip could shatter access to multiple vaccines by attacking adjuvants, childhood vaccines schedule and hepatitis B
ACIP has posted a draft agenda for their upcoming meeting on 12/4 and 12/5.
Alarm bells are blaring. They are going to spend the entire first day talking about the vaccine schedule.
There is no evidence whatsoever that there is any danger whatsoever with the current vaccine schedule.
Alarm bells are blaring. They are going to spend the entire first day talking about the vaccine schedule.
There is no evidence whatsoever that there is any danger whatsoever with the current vaccine schedule.
November 16, 2025 at 9:03 PM
This is fucking terrifying. In one meeting acip could shatter access to multiple vaccines by attacking adjuvants, childhood vaccines schedule and hepatitis B
Reposted by Chris Weston
Today, I say goodbye to an old friend—the #Biochemical #Pathways poster. It has hung in countless labs and offices, including on my own wall while I was studying #bioinformatics, inspiring my fascination with life’s chemistry. #science #legacy #Roche 💔💔💔
Roche | Biochemical Pathways
Biochemical Pathways provide an overview of the chemical reactions of cells in various species and organs.
www.roche.com
September 21, 2025 at 9:50 AM
Today, I say goodbye to an old friend—the #Biochemical #Pathways poster. It has hung in countless labs and offices, including on my own wall while I was studying #bioinformatics, inspiring my fascination with life’s chemistry. #science #legacy #Roche 💔💔💔
Reposted by Chris Weston
This is wild 🤩
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature
Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.
www.nature.com
January 23, 2025 at 9:22 PM
This is wild 🤩
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Chris Weston
THIS IS HUGE! Researchers at Stanford Medicine have devised an influenza vaccine that prompts immunity to ALL four major flu subtypes AND shows potential against bird flu, indicating a significant advancement in flu prevention and a potential increase in vaccine efficacy. Let’s talk about that! 🧪🧵⬇️
January 2, 2025 at 5:00 PM
THIS IS HUGE! Researchers at Stanford Medicine have devised an influenza vaccine that prompts immunity to ALL four major flu subtypes AND shows potential against bird flu, indicating a significant advancement in flu prevention and a potential increase in vaccine efficacy. Let’s talk about that! 🧪🧵⬇️
Reposted by Chris Weston
'Here, we show that this reagent appears to be unreliable due to providing false-positive signals at the expected molecular weight of Bax in immunoblotting experiments and likewise provides false-positive signals in immunofluorescence-based detection of Bax expression'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Why Bax detection in >1400 publications might be flawed - Cell Death & Disease
Cell Death & Disease - Why Bax detection in >1400 publications might be flawed
www.nature.com
December 26, 2024 at 3:22 PM
'Here, we show that this reagent appears to be unreliable due to providing false-positive signals at the expected molecular weight of Bax in immunoblotting experiments and likewise provides false-positive signals in immunofluorescence-based detection of Bax expression'
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Chris Weston
This is really disappointing- only 41.8% of eligible people have taken up the offer of an RSV vaccine! London has the lowest take up- 34.2%. Takeup in some ethnic groups such as S Asian as low as 14.3%- this clearly stores MUCH more work needed to communicate about this vaccine & its benefits 🧪
RSV vaccine coverage report in older adults for catch-up cohorts in England: November 2024
www.gov.uk
December 20, 2024 at 1:18 PM
This is really disappointing- only 41.8% of eligible people have taken up the offer of an RSV vaccine! London has the lowest take up- 34.2%. Takeup in some ethnic groups such as S Asian as low as 14.3%- this clearly stores MUCH more work needed to communicate about this vaccine & its benefits 🧪
Reposted by Chris Weston
Goldman Sachs analysts : The money men saying the quiet part out loud
Curing patients may not be a sufficiently profitable enterprise for biotech companies.
Chronic disease is a far more beneficial business model
www.cnbc.com/2018/04/11/g...
Curing patients may not be a sufficiently profitable enterprise for biotech companies.
Chronic disease is a far more beneficial business model
www.cnbc.com/2018/04/11/g...
Goldman Sachs asks in biotech research report: 'Is curing patients a sustainable business model?'
Goldman Sachs warns sales from the most successful disease treatments are difficult to maintain.
www.cnbc.com
December 18, 2024 at 10:48 AM
Goldman Sachs analysts : The money men saying the quiet part out loud
Curing patients may not be a sufficiently profitable enterprise for biotech companies.
Chronic disease is a far more beneficial business model
www.cnbc.com/2018/04/11/g...
Curing patients may not be a sufficiently profitable enterprise for biotech companies.
Chronic disease is a far more beneficial business model
www.cnbc.com/2018/04/11/g...
Reposted by Chris Weston
Sure, we can send you our dat
December 19, 2024 at 4:45 AM
Sure, we can send you our dat
Reposted by Chris Weston
New work from us:
Oral vancomycin is associated with attenuation in IBD activity in people with PSC. We also studied changes in gut microbiome profile, and key transcriptomic and metabolomic features.
academic.oup.com/ecco-jcc/adv...
Oral vancomycin is associated with attenuation in IBD activity in people with PSC. We also studied changes in gut microbiome profile, and key transcriptomic and metabolomic features.
academic.oup.com/ecco-jcc/adv...
Open label vancomycin in primary sclerosing cholangitis-inflammatory bowel disease: improved colonic disease activity and associations with changes in host-microbiome-metabolomic signatures
AbstractBackground. We conducted a single-arm interventional study, to explore mucosal changes associated with clinical remission under oral vancomycin (OV
academic.oup.com
December 14, 2024 at 1:18 PM
New work from us:
Oral vancomycin is associated with attenuation in IBD activity in people with PSC. We also studied changes in gut microbiome profile, and key transcriptomic and metabolomic features.
academic.oup.com/ecco-jcc/adv...
Oral vancomycin is associated with attenuation in IBD activity in people with PSC. We also studied changes in gut microbiome profile, and key transcriptomic and metabolomic features.
academic.oup.com/ecco-jcc/adv...
Reposted by Chris Weston
www.bbc.com/news/article...
Nice to see Debbie Shawcross (not on here yet!), @drgautammehta.bsky.social and others really highlighting this issue on various BBC platforms today!
#LiverSky
@adhanda.bsky.social
@aleksanderkrag.bsky.social
Nice to see Debbie Shawcross (not on here yet!), @drgautammehta.bsky.social and others really highlighting this issue on various BBC platforms today!
#LiverSky
@adhanda.bsky.social
@aleksanderkrag.bsky.social
‘At 31, I was told if I didn’t stop drinking, I could die’
BBC journalist Hazel Martin was told she had liver fibrosis and must go teetotal or she could die.
www.bbc.com
November 25, 2024 at 6:47 AM
www.bbc.com/news/article...
Nice to see Debbie Shawcross (not on here yet!), @drgautammehta.bsky.social and others really highlighting this issue on various BBC platforms today!
#LiverSky
@adhanda.bsky.social
@aleksanderkrag.bsky.social
Nice to see Debbie Shawcross (not on here yet!), @drgautammehta.bsky.social and others really highlighting this issue on various BBC platforms today!
#LiverSky
@adhanda.bsky.social
@aleksanderkrag.bsky.social
Reposted by Chris Weston
me (weighing chemicals): it says here the compound can be "a bit static-y" lol i'm sure it's fine
my spatula:
my spatula:
November 19, 2024 at 8:58 AM
me (weighing chemicals): it says here the compound can be "a bit static-y" lol i'm sure it's fine
my spatula:
my spatula:
Reposted by Chris Weston
Beautiful paper from Burkhard Ludewig’s group showing the importance of immunoregulatory stroma to support anti-tumour immunity.
www.cell.com/action/showP...
www.cell.com/action/showP...
www.cell.com
November 19, 2024 at 8:50 PM
Beautiful paper from Burkhard Ludewig’s group showing the importance of immunoregulatory stroma to support anti-tumour immunity.
www.cell.com/action/showP...
www.cell.com/action/showP...
Reposted by Chris Weston
I spoke to @mscribe.bsky.social @theguardian.com about the H5N1 case in BC.
More and more human cases are occurring, along with mutations that indicate further human adaptation.
We need to treat these cases like a warning, because that is what they are.
www.theguardian.com/world/2024/n...
More and more human cases are occurring, along with mutations that indicate further human adaptation.
We need to treat these cases like a warning, because that is what they are.
www.theguardian.com/world/2024/n...
Bird flu in Canada may have mutated to become more transmissible to humans
Scientists are racing to understand what a hospitalized teen’s case of bird flu may mean for future outbreaks
www.theguardian.com
November 19, 2024 at 7:11 PM
I spoke to @mscribe.bsky.social @theguardian.com about the H5N1 case in BC.
More and more human cases are occurring, along with mutations that indicate further human adaptation.
We need to treat these cases like a warning, because that is what they are.
www.theguardian.com/world/2024/n...
More and more human cases are occurring, along with mutations that indicate further human adaptation.
We need to treat these cases like a warning, because that is what they are.
www.theguardian.com/world/2024/n...