@chopralab.bsky.social
Reposted
Joining us from Purdue, Prof. Gaurav Chopra will be giving a Chemical Biology Seminar on "How do Glial and Immune Cells become Dysfunctional in Aging and Neurodegeneration?" today at 3PM in STLC 114. chemistry.stanford.edu/events/chemi...
Chemical Biology Seminar: Professor Gaurav Chopra, Purdue University | Chemistry
About the Seminar"How do Glial and Immune Cells become Dysfunctional in Aging and Neurodegeneration?"Pathogenic aging leads to neurodegeneration and imposes chronic metabolic stress on the brain, rewi...
chemistry.stanford.edu
November 4, 2025 at 5:48 PM
Joining us from Purdue, Prof. Gaurav Chopra will be giving a Chemical Biology Seminar on "How do Glial and Immune Cells become Dysfunctional in Aging and Neurodegeneration?" today at 3PM in STLC 114. chemistry.stanford.edu/events/chemi...
🚨 Catch the MIND Lab at #ASMS2025! Our trainees present cutting-edge work on AI-agents, lipidomics, & neurodegeneration in talks & posters all week. From AI-agents to single-cell FA profiling to PROTAC proteomics—don’t miss it!🧠#AIagents #Neuroimmunology #Lipidomics
@asms.org
@asms.org
May 31, 2025 at 9:17 PM
🚨 Catch the MIND Lab at #ASMS2025! Our trainees present cutting-edge work on AI-agents, lipidomics, & neurodegeneration in talks & posters all week. From AI-agents to single-cell FA profiling to PROTAC proteomics—don’t miss it!🧠#AIagents #Neuroimmunology #Lipidomics
@asms.org
@asms.org
Our Immunity @cp-immunity.bsky.social Cover was not selected but nothing can hold back the Microglia super-heroine when she has DGAT2-blocking beverage. #NotTheCover Read the full article in Immunity: www.cell.com/immunity/ful...
Meet M, our microglia superheroine 🦸♀️💥
After chugging the magical DGAT2-Stop! Kool-Aid 💊🧃, she breaks free from her lipid droplet shackles 💥💪
Supercharged, she lifts the amyloid beams 🧱 trapping neurons and saves the city of Brain 🧠🏙️!
Our cover submission for @cp-immunity.bsky.social. #notthecover
After chugging the magical DGAT2-Stop! Kool-Aid 💊🧃, she breaks free from her lipid droplet shackles 💥💪
Supercharged, she lifts the amyloid beams 🧱 trapping neurons and saves the city of Brain 🧠🏙️!
Our cover submission for @cp-immunity.bsky.social. #notthecover
May 21, 2025 at 7:22 PM
Our Immunity @cp-immunity.bsky.social Cover was not selected but nothing can hold back the Microglia super-heroine when she has DGAT2-blocking beverage. #NotTheCover Read the full article in Immunity: www.cell.com/immunity/ful...
Reposted
Microglia: A super-heroine that had a DGAT2-blocking beverage (cans) so she could break the chains from lipid droplets holding her back (LD weights) and lift the amyloid load (beams) that trapped the neurons, thereby rescuing them in the aged Brain (City sign)! #NotTheCover @cp-immunity.bsky.social
May 21, 2025 at 5:55 PM
Microglia: A super-heroine that had a DGAT2-blocking beverage (cans) so she could break the chains from lipid droplets holding her back (LD weights) and lift the amyloid load (beams) that trapped the neurons, thereby rescuing them in the aged Brain (City sign)! #NotTheCover @cp-immunity.bsky.social
Reposted
Why do the brain’s professional phagocytes stop clearing amyloid in Alzheimer’s disease? Can we restore microglial superpowers & rescue dying neurons in AD? YES, by stopping DGAT2-mediated lipid droplet formation! Checkout our latest manuscript @cp-immunity.bsky.social 👇🏼
www.cell.com/immunity/abs...
www.cell.com/immunity/abs...
Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease
Why microglia stop reducing amyloid deposits from Alzheimer’s disease (AD) brains
is unknown. Prakash, Manchanda, et al. show that microglia increase their lipid droplets
and lose their phagocytic cap...
www.cell.com
May 19, 2025 at 5:09 PM
Why do the brain’s professional phagocytes stop clearing amyloid in Alzheimer’s disease? Can we restore microglial superpowers & rescue dying neurons in AD? YES, by stopping DGAT2-mediated lipid droplet formation! Checkout our latest manuscript @cp-immunity.bsky.social 👇🏼
www.cell.com/immunity/abs...
www.cell.com/immunity/abs...
Reposted
Happy to share that our work "Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease" is out now @cp-immunity.bsky.social! ➡️ www.cell.com/immunity/ful...
Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease
Why microglia stop reducing amyloid deposits from Alzheimer’s disease (AD) brains
is unknown. Prakash, Manchanda, et al. show that microglia increase their lipid droplets
and lose their phagocytic cap...
www.cell.com
May 19, 2025 at 6:14 PM
Happy to share that our work "Amyloid-β induces lipid droplet-mediated microglial dysfunction via the enzyme DGAT2 in Alzheimer’s disease" is out now @cp-immunity.bsky.social! ➡️ www.cell.com/immunity/ful...