9/ #MentalDisorders affect ~1 billion people, with a higher burden in women and older adults. They account for 5% of global health loss. Innovation is slow, and promising treatments like #psychedelics remain underused. It’s time to rethink mental health care. #MentalHealth

8/ Methodological Gaps:
• YLLs are underestimated, suicide not included under mental disorders
• Some disorders (e.g., binge eating, personality disorders) not fully captured
• Reliance on diagnostic data from high-income countries limits global comparability

7/ Countries with the greatest mental health burden include the U.S., Australia, New Zealand, Brazil, Spain, Greece, and Uganda.
Sub-Saharan Africa and the Middle East show elevated prevalence for depressive disorders. Mental health is a global issue, with local urgency.

6/ Age distribution:
• Burden begins before age 5 with intellectual and developmental disabilities and autism
• Peaks between ages 25–34
• Declines after 35, but remains significant
Mental disorders affect people across all stages of life.

5/ Mental health burden is higher in females (1703 vs 1426 DALYs/100k).
• Depression (4158 F vs 2713 M), anxiety (4694 F vs 2859 M), and eating disorders (231 F vs 117 M) affect women more.
• ADHD (1611 M vs 631 F) and autism are more common in men ( 560 M vs 176 F).

4/ The most important mental conditions:
• Depressive disorders: 37.3% of DALYs from mental disorders
• Anxiety disorders: 22.9%
Depression and anxiety remain the most common disorders with a great impact globally. The least common were schizophrenia and eating disorders.

3/ While the overall burden has grown, age- and population-adjusted rates remain unchanged, suggesting that advances in prevention and treatment haven't kept pace with global growth. Mental disorders now account for nearly 5% of the global health burden.

2/ Between 1990 and 2019, the number of years lost to disability or early death due to mental disorders (measured as DALYs) increased by more than 50 percent, from 80.8M to 125.3M cases worldwide.