CHASERR Dad (Brian Broadbent)
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chaserrdad.bsky.social
CHASERR Dad (Brian Broadbent)
@chaserrdad.bsky.social
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Father of child with first neurological disease caused by a lncRNA (now published in NEJM). Hunting for a cure. Non-coding disease advocate. Based in Dallas, TX.
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Reposted by CHASERR Dad (Brian Broadbent)
t-tsarouchas.bsky.social
Now out in Molecular Therapy! With Francesca Vacante, we describe MYRACL, a novel candidate lncRNA driving human oligodendroglia differentiation & myelination. Grateful to our amazing co-authors & mentors @annawilliamslab.bsky.social & Andrew Baker!

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www.sciencedirect.com/science/arti...
August 15, 2025 at 3:41 AM
Reposted by CHASERR Dad (Brian Broadbent)
igorulitsky.bsky.social
Stop the doom scrolling! A new 🗞️ from my lab, describing one of our flagship projects of many years we are super excited to share:
"Inducible formation of fusion transcripts upregulates haploinsufficient CHD2 gene expression".
A 🧵
biorxiv.org/content/earl...
Inducible formation of fusion transcripts upregulates haploinsufficient CHD2 gene expression
Modes of action of long noncoding RNAs (lncRNAs) are poorly understood. CHASERR is a broadly expressed lncRNA located immediately upstream of the promoter of the CHD2 gene. We show that antisense olig...
biorxiv.org
May 29, 2025 at 12:35 PM