Chai Ann Ng
@chaiannng.bsky.social
ClinGen VCEP members for cardiac potassium and sodium channels. I provide functional data using Automated Patch Clamp as evidence for VUS reclassification in channelopathies. Disclaimer: “Opinions expressed are my own.”
Thanks to the British Society for Genetic Medicine for the nice video. It will be midnight in Sydney, so I will have plenty of coffee to stay awake.
November 26, 2025 at 6:21 AM
Thanks to the British Society for Genetic Medicine for the nice video. It will be midnight in Sydney, so I will have plenty of coffee to stay awake.
#HGSA2025 was a great meeting; I presented my research in the Top Orals session to colleagues from clinical diagnostic labs. We must collaborate to improve the genetic diagnosis of channelopathies, especially for missense variants.
August 18, 2025 at 9:59 AM
#HGSA2025 was a great meeting; I presented my research in the Top Orals session to colleagues from clinical diagnostic labs. We must collaborate to improve the genetic diagnosis of channelopathies, especially for missense variants.
Spreading the word to cardiologists at CSANZ meeting on how functional data can help with variant reclassification in cardiac channelopathies and sometimes in risk prediction as well. Hopefully more of them are aware of our research.
August 16, 2025 at 9:24 PM
Spreading the word to cardiologists at CSANZ meeting on how functional data can help with variant reclassification in cardiac channelopathies and sometimes in risk prediction as well. Hopefully more of them are aware of our research.
We have previously demonstrated that functional data can inform us about the risk associated with KCNH2-LQTS (www.ahajournals.org/doi/10.1161/...). By using the same functional data, we asked what is the utility when applied in clinical setting by collaborate with Invitae Corp to reanalyse their VUS
July 31, 2025 at 1:11 AM
We have previously demonstrated that functional data can inform us about the risk associated with KCNH2-LQTS (www.ahajournals.org/doi/10.1161/...). By using the same functional data, we asked what is the utility when applied in clinical setting by collaborate with Invitae Corp to reanalyse their VUS
Leaving Tokyo after presenting at Membrane Physiology Symposium Japan. Met new colleagues and discussed potential collaboration :) Thanks to @naniontech.bsky.social for the invitation.
July 18, 2025 at 1:26 PM
Leaving Tokyo after presenting at Membrane Physiology Symposium Japan. Met new colleagues and discussed potential collaboration :) Thanks to @naniontech.bsky.social for the invitation.
The Membrane Physiology Symposium (MPS) is now also taking place in Japan. During 17-18 July, I'll be in Tokyo to present our research on Brugada Syndrome, where we used automated patch clamp to quantify the function of Nav1.5 #ionchannel related to 252 unique SCN5A variants identified in patients.
July 6, 2025 at 12:41 AM
The Membrane Physiology Symposium (MPS) is now also taking place in Japan. During 17-18 July, I'll be in Tokyo to present our research on Brugada Syndrome, where we used automated patch clamp to quantify the function of Nav1.5 #ionchannel related to 252 unique SCN5A variants identified in patients.
I am around, let’s see if I will bump into you!
April 25, 2025 at 2:18 PM
I am around, let’s see if I will bump into you!
I didn’t attend this GRC Cardiac Arrhythmia Mechanisms in Italy, but my PhD student, Joanne Ma, went and presented her SCN5A #ionchannel patch clamp assay and received a runner-up poster prize. She also received two job offers at the GRC meeting, which will boost her confidence.
March 15, 2025 at 1:19 AM
I didn’t attend this GRC Cardiac Arrhythmia Mechanisms in Italy, but my PhD student, Joanne Ma, went and presented her SCN5A #ionchannel patch clamp assay and received a runner-up poster prize. She also received two job offers at the GRC meeting, which will boost her confidence.
Bringing my medicine honours students to visit the Heart Centre for Children at the Children’s Hospital at Westmead. Thanks 🙏 to Dr Hiroko and Dr Christian for having them. I am sure Lily Cai and Angela Rofail will learn a lot today and may also help their honours projects on Long QT Syndrome
March 13, 2025 at 1:32 AM
Bringing my medicine honours students to visit the Heart Centre for Children at the Children’s Hospital at Westmead. Thanks 🙏 to Dr Hiroko and Dr Christian for having them. I am sure Lily Cai and Angela Rofail will learn a lot today and may also help their honours projects on Long QT Syndrome
Proud moment as a supervisor when my medicine honours student from last year received the "Student Researcher of the Year Award" from the UNSW St Vincent’s Clinical School. Jess established our SCN2A #ionchannel patch clamp assay to study variants of uncertain significance detected in Australia.
March 7, 2025 at 11:27 AM
Proud moment as a supervisor when my medicine honours student from last year received the "Student Researcher of the Year Award" from the UNSW St Vincent’s Clinical School. Jess established our SCN2A #ionchannel patch clamp assay to study variants of uncertain significance detected in Australia.
Attended the 2024 Excellence in Cardiovascular Research ACvA Awards Ceremony at Custom House in Brisbane. I am very happy to be a finalist for the Game Changer Award and the award goes to Prof John Fraser.
February 20, 2025 at 1:18 PM
Attended the 2024 Excellence in Cardiovascular Research ACvA Awards Ceremony at Custom House in Brisbane. I am very happy to be a finalist for the Game Changer Award and the award goes to Prof John Fraser.
A Christmas Carol light projection on St Mary’s Cathedral. Great fun for the kids.
December 24, 2024 at 10:28 AM
A Christmas Carol light projection on St Mary’s Cathedral. Great fun for the kids.
It’s the same house but with 3 different views. We brought the kids to visit the Christmas lights display every year. Maybe around 15 houses on the same streets were decorated, raising fund for Bear Cottage, Sydney Children's hospice.
December 22, 2024 at 12:34 PM
It’s the same house but with 3 different views. We brought the kids to visit the Christmas lights display every year. Maybe around 15 houses on the same streets were decorated, raising fund for Bear Cottage, Sydney Children's hospice.
Editorial by Barry London for our recent KCNH2 paper (DOI: 10.1161/CIRCULATIONAHA.124.069828).
#cardiosky
#ionchannels
DOI: 10.1161/CIRCULATIONAHA.124.072169
#cardiosky
#ionchannels
DOI: 10.1161/CIRCULATIONAHA.124.072169
December 2, 2024 at 9:56 PM
Editorial by Barry London for our recent KCNH2 paper (DOI: 10.1161/CIRCULATIONAHA.124.069828).
#cardiosky
#ionchannels
DOI: 10.1161/CIRCULATIONAHA.124.072169
#cardiosky
#ionchannels
DOI: 10.1161/CIRCULATIONAHA.124.072169
Very proud of my honours students who were awarded with “Exceptional Speaker” and “Outstanding Poster” for their presentations at the @ausgenomics.bsky.social AFGN symposium.
@victorchang.edu.au
@emmagenetics.bsky.social
@victorchang.edu.au
@emmagenetics.bsky.social
November 29, 2024 at 8:02 AM
Very proud of my honours students who were awarded with “Exceptional Speaker” and “Outstanding Poster” for their presentations at the @ausgenomics.bsky.social AFGN symposium.
@victorchang.edu.au
@emmagenetics.bsky.social
@victorchang.edu.au
@emmagenetics.bsky.social
One day to go for the @ausgenomics.bsky.social AFGN symposium in Melbourne. My students and I took this opportunity to present our patch clamp results for SCN1A and SCN2A to Sam and Michael (Ingrid was away) from Epilepsy Research Centre located at Melbourne Brain Centre, Heidelberg.
#ionchannels
#ionchannels
November 27, 2024 at 6:16 AM
One day to go for the @ausgenomics.bsky.social AFGN symposium in Melbourne. My students and I took this opportunity to present our patch clamp results for SCN1A and SCN2A to Sam and Michael (Ingrid was away) from Epilepsy Research Centre located at Melbourne Brain Centre, Heidelberg.
#ionchannels
#ionchannels
Thanks for the inspiration. This is me.
November 24, 2024 at 11:19 AM
Thanks for the inspiration. This is me.
My kids requested I bought back some Maple syrup when I was in Vancouver. Got a bottle from Granville Island and tasted it today and we like it.
November 23, 2024 at 10:00 PM
My kids requested I bought back some Maple syrup when I was in Vancouver. Got a bottle from Granville Island and tasted it today and we like it.
It was my pleasure to visit the British Columbia Inherited Arrhythmia Program at St Paul’s Hospital and met Andrew and Brianna. Hopefully I will be able to work with HiRO in 2025. #cardiosky
November 22, 2024 at 1:15 AM
It was my pleasure to visit the British Columbia Inherited Arrhythmia Program at St Paul’s Hospital and met Andrew and Brianna. Hopefully I will be able to work with HiRO in 2025. #cardiosky
#HRS2025 is in San Diego (24-27 Apr 2025). I am extremely excited to present my research in the Cardiac EPS Annual Meeting, which would be on Day 1 of HRS2025. The theme this year is “A pathway to precision electrophysiology”.
tinyurl.com/5a6rrteu
tinyurl.com/5a6rrteu
November 20, 2024 at 10:57 AM
#HRS2025 is in San Diego (24-27 Apr 2025). I am extremely excited to present my research in the Cardiac EPS Annual Meeting, which would be on Day 1 of HRS2025. The theme this year is “A pathway to precision electrophysiology”.
tinyurl.com/5a6rrteu
tinyurl.com/5a6rrteu
As my first post, I present you with a summary figure of the patch-clamp data that was used in the #KCNH2 paper but it was not actually in the paper, but I quite like it, so I published it here at Bluesky🙂
November 20, 2024 at 8:59 AM
As my first post, I present you with a summary figure of the patch-clamp data that was used in the #KCNH2 paper but it was not actually in the paper, but I quite like it, so I published it here at Bluesky🙂