Rimas Orentas
@cgtgaithersburg.bsky.social
Immunotherapy R&D - looking to develop immunotherapy, cell and gene therapy, and make an end to sickle cell disease.
Are you using the right tumor micro environment model? Cancer is a disease of aging @sitcancer.bsky.social #SITC25 great session at the annual meeting on the aged immune system and the tumor micro environment moderated by Drs DA and A Weeraratna.
November 7, 2025 at 9:28 PM
Are you using the right tumor micro environment model? Cancer is a disease of aging @sitcancer.bsky.social #SITC25 great session at the annual meeting on the aged immune system and the tumor micro environment moderated by Drs DA and A Weeraratna.
Great session exploring neuro-immunology in cancer immunotherapy #SITC25. Clearly we have much to learn about this little studied part of tumor biology. U Von Adrian demonstrated how afferent neurons organize and activate MDSCs at the tumor site @sitcancer.bsky.social
November 7, 2025 at 3:44 PM
Great session exploring neuro-immunology in cancer immunotherapy #SITC25. Clearly we have much to learn about this little studied part of tumor biology. U Von Adrian demonstrated how afferent neurons organize and activate MDSCs at the tumor site @sitcancer.bsky.social
Hill Day @sitcancer.bsky.social sharing our support for the NIH and immunotherapy for cancer w Dr Robyn Gartrell and Andrew Donlon from Rep McClain Delaney’s House Office. Thanks also to staffers from Sen Van Hollen and Alsobrooks office for hosting us as well.
November 5, 2025 at 10:10 PM
Hill Day @sitcancer.bsky.social sharing our support for the NIH and immunotherapy for cancer w Dr Robyn Gartrell and Andrew Donlon from Rep McClain Delaney’s House Office. Thanks also to staffers from Sen Van Hollen and Alsobrooks office for hosting us as well.
Leroy Hood holds forth on the future of genomics and phenomics. Just as we only now have incorporated epigenomics into human biology- there is likely still missing major data sets to allow new advances to come. i e. one proteins can be modified 400 different ways. @systemsbiology.bsky.social
October 28, 2025 at 1:28 AM
Leroy Hood holds forth on the future of genomics and phenomics. Just as we only now have incorporated epigenomics into human biology- there is likely still missing major data sets to allow new advances to come. i e. one proteins can be modified 400 different ways. @systemsbiology.bsky.social
The CAR-T therapy team at Taichung medical center in Taiwan - amazing world class work. This includes new CARs from #Miltenyi, Novartis Tcharge for autoimmune disease and a robust regenerative medicine program
October 25, 2025 at 4:26 AM
The CAR-T therapy team at Taichung medical center in Taiwan - amazing world class work. This includes new CARs from #Miltenyi, Novartis Tcharge for autoimmune disease and a robust regenerative medicine program
#UNGA80 #ECSA East, Central, Southern Africa Session at the UN General Assembly Mtg #ScienceDiplomacy chair Prof Ntobeko Ntusi looking to bridge divides through shared knowledge and establishing regional centers of excellence. We are here to advocate for global health for the UN Pact for the Future
September 26, 2025 at 12:20 PM
#UNGA80 #ECSA East, Central, Southern Africa Session at the UN General Assembly Mtg #ScienceDiplomacy chair Prof Ntobeko Ntusi looking to bridge divides through shared knowledge and establishing regional centers of excellence. We are here to advocate for global health for the UN Pact for the Future
Having visited private and public institutes (view is the medical school at Albert Einstein SOM in São Paulo)- I am inspired by the new approaches for cell and gene therapy. Most of the world has looked at what our “market” has produced and is creating affordable alternatives
August 21, 2025 at 11:44 AM
Having visited private and public institutes (view is the medical school at Albert Einstein SOM in São Paulo)- I am inspired by the new approaches for cell and gene therapy. Most of the world has looked at what our “market” has produced and is creating affordable alternatives
Dr Hanahan wins the Pezcoller! #AACR25 @theaacr.bsky.social and published today the IL-1 signature of tumors induces systemic immunosuppression_ and is reversed by anti- IL-RAP antibody.
April 27, 2025 at 5:46 PM
Dr Hanahan wins the Pezcoller! #AACR25 @theaacr.bsky.social and published today the IL-1 signature of tumors induces systemic immunosuppression_ and is reversed by anti- IL-RAP antibody.
Wonderful overview today by Ken Anderson @theaacr.bsky.social #AACR25 of the advances in MM- adding CARs to degraders (imids) and blockers (bortezomib) both of which also have immune activity has completely changed the outlook for patients- and that’s why we are here
April 26, 2025 at 11:29 PM
Wonderful overview today by Ken Anderson @theaacr.bsky.social #AACR25 of the advances in MM- adding CARs to degraders (imids) and blockers (bortezomib) both of which also have immune activity has completely changed the outlook for patients- and that’s why we are here
Dr S Davies from cincinnatichildren’s presents a challenge-using a new vector system and reduced intensity conditioning to keep #sicklecell therapy low cost by keeping the process in academic medical centers & not a strictly high-priced pharma product @ascaa.bsky.social @astct.bsky.social #Tandem25
February 14, 2025 at 7:20 PM
Dr S Davies from cincinnatichildren’s presents a challenge-using a new vector system and reduced intensity conditioning to keep #sicklecell therapy low cost by keeping the process in academic medical centers & not a strictly high-priced pharma product @ascaa.bsky.social @astct.bsky.social #Tandem25
Dr M Bleakly from @fredhutch.bsky.social delivering a master class on using minor antigens to create anti-leukemia T cells in the context of HSCT @astct.bsky.social #Tandem25 incredible analysis of hematologic restricted targets
February 14, 2025 at 3:39 AM
Dr M Bleakly from @fredhutch.bsky.social delivering a master class on using minor antigens to create anti-leukemia T cells in the context of HSCT @astct.bsky.social #Tandem25 incredible analysis of hematologic restricted targets
Dr N Shah from MCW presenting Tandem CD20-19 CAR-T using fresh in/fresh out manufacturing allowing many patients to receive this therapy who otherwise would not qualify @astct.bsky.social #Tandem25
February 14, 2025 at 1:32 AM
Dr N Shah from MCW presenting Tandem CD20-19 CAR-T using fresh in/fresh out manufacturing allowing many patients to receive this therapy who otherwise would not qualify @astct.bsky.social #Tandem25
Andy Sharenberg #UmojaBio presents the direct in vivo platform to create CAR-T #Tandem2025
February 12, 2025 at 8:48 PM
Andy Sharenberg #UmojaBio presents the direct in vivo platform to create CAR-T #Tandem2025
The durability of cure for ADA-SCID with lentiviral vectors is amazing. Rarity, a public benefit corp., has been formed to carry this therapy forward where previous models have failed #ASH24 Dr M Masiuk presented the plot below-one of many showing the durability of correction #kohnlab #rarity #CIRM
December 10, 2024 at 12:45 AM
Dr I Odame sharing a vision to make high impact changes on sickle cell disease care in Africa that will scale #ASH24 Hydroxyurea access must be the cornerstone #CONSA #sicklecell
December 9, 2024 at 7:29 PM
Dr I Odame sharing a vision to make high impact changes on sickle cell disease care in Africa that will scale #ASH24 Hydroxyurea access must be the cornerstone #CONSA #sicklecell
Mind-blowing results showing a ketogenic diet or just the metabolite BHB strongly activates CAR-T activity in mice #ASH24 @ruellalab.bsky.social data demonstrate nice impact on cellular respiration (OCR)
December 8, 2024 at 11:30 PM
Mind-blowing results showing a ketogenic diet or just the metabolite BHB strongly activates CAR-T activity in mice #ASH24 @ruellalab.bsky.social data demonstrate nice impact on cellular respiration (OCR)
Dr Y Del-Adomakoh presents Hemoglobin SC (HbSC) disease study from Ghana and shows increased fetal globin, improved symptoms- although some DLTs were seen #ASH24 #sicklecell
December 8, 2024 at 11:10 PM
Dr Y Del-Adomakoh presents Hemoglobin SC (HbSC) disease study from Ghana and shows increased fetal globin, improved symptoms- although some DLTs were seen #ASH24 #sicklecell
December 8, 2024 at 6:01 PM