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Cell Regeneration
@cell-regeneration.bsky.social
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Cell Regeneration, a fully Open Access journal officially affiliated with the Chinese Society for Cell Biology, covers research on stem cell biology, regenerative biology, and related clinical translation.
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cell-regeneration.bsky.social
Cell Regen Research | α-Ketoglutarate boosts skin flap survival! 🩹 Enhances angiogenesis via PI3K/Akt/HIF-1α in ischemic flaps. #Angiogenesis #WoundHealing
🔗 Full paper at: doi.org/10.1186/s136...
Impact of α-KG treatment on skin flaps
December 22, 2025 at 9:16 AM
cell-regeneration.bsky.social
Cell Regen Review | Imaging + single-cell omics: a new paradigm in developmental biology! 🔬Super-resolution & light-sheet meet spatial transcriptomics for multi-scale insights. #DevelopmentalBiology #SingleCellOmics
🔗 Full paper at: doi.org/10.1186/s136...
Integrating imaging technologies with single-cell & spatial omics – a new paradigm for developmental biology
December 17, 2025 at 9:15 AM
cell-regeneration.bsky.social
Cell Regen Research | 🎯Direct Oct4 targets in ESCs revealed! Auxin-inducible degron (AID) system + nascent RNA-seq uncovers immediate transcriptional changes in pluripotency genes & non-coding RNAs. #StemCells #Pluripotency
🔗 Full paper at: doi.org/10.1186/s136...
Identification of direct OCT4 targets through integration of OCT4 ChIP-seq and nascent RNA-seq data
December 15, 2025 at 9:02 AM
cell-regeneration.bsky.social
Cell Regen Report | Major step forward in 🦷 regeneration! New N2B27-based culture medium keeps mouse dental mesenchymal cells odontogenic for 14 days — BMP4 down, OPN/ATRA — enabling regenerative teeth in vivo. #ToothRegeneration #mesenchymalcells
🔗 Full paper at: doi.org/10.1186/s136...
The proposed mechanism for maintaining the odontogenic potential in dental mesenchymal cells (DMCs) using the novel N2B27-based culture medium
December 10, 2025 at 8:48 AM
cell-regeneration.bsky.social
Cell Regen Research | 🔎Single-cell atlas reveals lifelong evolution of bone marrow vascular niche! From fetal liver to aged BM, Midkine emerges as a new regulator of HSPC reconstitution. #Hematopoiesis #StemCellNiche
🔗 Full paper at: doi.org/10.1186/s136...
A single-cell journey through the bone marrow vascular niche across life – meet the new player, Midkine!
December 4, 2025 at 8:25 AM
cell-regeneration.bsky.social
Cell Regen Review | Poly(A) tails: the hidden switch in stem cell fate & early development! Length dynamics drive mRNA stability & translation. #StemCells #RNAbiology
🔗 Full review at: doi.org/10.1186/s136...
Regulation of Poly(A)-tails in stem cell and early development
December 2, 2025 at 6:22 AM
cell-regeneration.bsky.social
Cell Regen Review | 📝Hypoxic–ischemic preconditioning (H/IPC) protects the 🧠 via mitochondrial metabolism—H/IPC boosts mitophagy, curbs fission & apoptosis for neuroprotection. #Mitochondria #Neuroprotection
🔗 More at: doi.org/10.1186/s136...
Hypoxic–ischemic preconditioning regulates mitochondrial metabolism
November 27, 2025 at 1:43 AM
cell-regeneration.bsky.social
Cell Regen Research | Posterior enhancer (p-Enh) maintains neuromesodermal progenitor bi-potency during gastrulation! Deletion biases fate toward presomitic mesoderm, thereby disrupting spinal cord development. #StemCells #Embryogenesis
🔗 More at: doi.org/10.1186/s136...
p-Enh deletion disrupts NMPs’ bi-potency and biases lineage commitment toward PSM fate across in vitro, in vivo, and in silico models
November 24, 2025 at 8:43 AM
cell-regeneration.bsky.social
Cell Regen Report | Validating quality standards for primary human hepatocytes! ✅ Tested viability, markers & metabolism in hepatocytes, revealing heterogeneity for liver studies. #Hepatocytes #CellBiology
🔗 More at: doi.org/10.1186/s136...
Single cell transcriptomic analysis on six primary human hepatocytes
October 17, 2025 at 7:42 AM
cell-regeneration.bsky.social
Cell Regen Review | Rewiring cardiomyocyte identity & metabolism for heart regeneration! 🫀 Strategies for improving cardiac function in animal models. #HeartRegeneration #StemCells
🔗 More at: doi.org/10.1186/s136...
Schematic overview of cardiomyocyte regulators orchestrating the dedifferentiation, proliferation, and redifferentiation process
September 28, 2025 at 8:53 AM
cell-regeneration.bsky.social
Cell Regen Review | Cell Regen Review | Drug-induced beta cell regeneration for diabetes! 🩺 Small molecules & pathways target proliferation to restore insulin production. #Diabetes #StemCells
🔗 More at: doi.org/10.1186/s136...
DOI: https://doi.org/10.1186/s13619-025-00255-9
September 8, 2025 at 6:20 AM
cell-regeneration.bsky.social
Cell Regen Review | What tech is advancing central nervous system repair in neural regeneration? 🧠Optogenetics, gene editing, 3D culture, single-cell sequencing, 3D imaging and more… #NeuralRegeneration #StemCells
🔗More at: doi.org/10.1186/s136...
3D imaging of neural tissues using advanced tissue clearing and Light-sheet microscopy
September 5, 2025 at 9:18 AM
cell-regeneration.bsky.social
✨Cell Regen Highlight | Transgene-free mouse embryo models via chemical reprogramming reach early organogenesis! Advances in PSC-derived iEFC-EMs & TF-SEMs for development & regen med. #StemCells #EmbryoModels
More at: doi.org/10.1186/s136...
DOI: https://doi.org/10.1186/s13619-025-00259-5
September 4, 2025 at 8:44 AM
cell-regeneration.bsky.social
Cell Regen Research | CD44 & Nucleolin regulate gliogenesis after spinal cord injury! scRNA-seq reveals SPP1-CD44 in microglia inflammation & PTN-NCL in astrocyte proliferation. #Inflammation #Gliogenesis
🔗More at: doi.org/10.1186/s136...
Microglial subpopulation subdivision and functional analysis showing CD44 as a key receptor regulating the inflammatory response
August 15, 2025 at 7:17 AM
cell-regeneration.bsky.social
Cell Regen Review | FGSCs: Hope for ovarian repair & fertility preservation! 🧬 Recent advances in stem cells for aging/damaged ovaries, with challenges ahead. #StemCells #Fertility 🔗 doi.org/10.1186/s136...
Pathways for FGSCs to restore ovarian function (Modified from Servier Medical Art)
August 13, 2025 at 12:44 AM
cell-regeneration.bsky.social
Cell Regen Review | Insights into tooth regeneration! 🦷 Stem cells & scaffolds drive pulp-dentin trials, while enamel repair evolves. #ToothRegeneration #StemCells
🔗Read more: doi.org/10.1186/s136...
Schematic of tooth regeneration process
August 4, 2025 at 9:10 AM
cell-regeneration.bsky.social
Cell Regen Research | 10-species microbial signature for IBD diagnosis. 🩺 XGBoost model (XGB-IBD10) achieves 87% accuracy!🎯 #IBD #Microbiome
🔗 doi.org/10.1186/s136...
XGB-IBD10 achieves a better performance than other top species-based methods
July 15, 2025 at 8:03 AM
cell-regeneration.bsky.social
Cell Regen Research | MANF-modified Schwann cells (SC) boost peripheral nerve repair! 🧠 Enhances axon regeneration & SC dynamics. ✨ #NerveRegeneration #SchwannCells
🔗 doi.org/10.1186/s136...
Schwann cells expressing Dox-inducible MANF protect axons and promote regeneration
July 7, 2025 at 8:50 AM
cell-regeneration.bsky.social
Cell Regen Research | Got a gut feeling? HIFT boosts microbiota diversity & Faecalibacterium for better gut health!💪 #GutMicrobiota #GutHealth #Exercise
📖https://doi.org/10.1186/s13619-025-00244-y
Characteristics of microbial alpha-diversity and beta-diversity among MICT, HIIT and HIFT
July 3, 2025 at 8:58 AM
cell-regeneration.bsky.social
Cell Regen Letter | YTHDF2-KIF26B-Wnt loop drives intestinal stem cell stemness! m6A reader YTHDF2 regulates Wnt signaling, with compensatory mechanisms revealed👇.
📖 doi.org/10.1186/s136...
#StemCells #GutHealth
A positive-feedback loop formed by YTHDF2-KIF26B-Wnt signaling maintains the stemness of ISCs
June 23, 2025 at 8:56 AM
cell-regeneration.bsky.social
🎊Latest on Cell Regeneration! We maintain our strong position in Clarivate #JCR2025: IF=4.7!
🔬 Q2 in Cell & Tissue Engineering (Top 31%)
🧫 Q2 in Cell Biology (Top 34%)
Grateful to our authors, reviewers & readers! #ImpactFactor #ScienceMetrics #Stemcells
🔗 cellregeneration.springeropen.com
Cell Regeneration
Cell Regeneration is officially affiliated with the Chinese Society for Cell Biology (CSCB).  It aims to become an international academic platform for the ...
cellregeneration.springeropen.com
June 18, 2025 at 8:41 AM
cell-regeneration.bsky.social
Cell Regen Research | Mongolian medicine Eerdun-Wurile boosts heart regeneration in zebrafish! 🫀 Enhances cardiomyocyte proliferation via MVDA, offering myocardial infarction therapy insights. #Cardiology #Regeneration
🔗 doi.org/10.1186/s136...
Eerdun-Wurile effectively restores heart function in zebrafish Representative heartbeat fluctuations charts of zebrafish in control
June 6, 2025 at 9:27 AM
cell-regeneration.bsky.social
Cell Regen Research | ⚙️Deep learning measures single-cell stiffness! High-throughput, non-invasive models predict MSC & macrophage mechanics, advancing mechanobiology. #DeepLearning #Biomechanics
🔗 Full study at: cellregeneration.springeropen.com/articles/10....
Schematic representation for the image-based cell stiffness evaluation using deep learning
June 5, 2025 at 9:19 AM
cell-regeneration.bsky.social
Cell Regen Review | New review explores alternative splicing’s role in stem cell fate & development! Splicing factors & emerging tech like CRISPR shape the future. #StemCells #Differentiation
📖Full study: cellregeneration.springeropen.com/articles/10....
Emerging technologies in alternative splicing research
June 4, 2025 at 8:22 AM
cell-regeneration.bsky.social
Cell Regen Research | Unlocking stem cell potential! Inhibiting METTL3 boosts naïve pluripotency via m6A-YTHDF2-Gstp1, enhancing reprogramming. #StemCells #Epigenetics
📖Full study: cellregeneration.springeropen.com/articles/10....
Schematic diagram of the regulatory mechanism of METTL3-m6A-YTHDF2 axis in PNT
May 29, 2025 at 11:12 AM