Dr. Casey Middleton
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caseymiddleton.bsky.social
Dr. Casey Middleton
@caseymiddleton.bsky.social
Infectious disease modeling
Views are my own
FWIW: I know there are bigger problems to solve in this world right now, but this one just seems so attainable!
October 1, 2025 at 6:27 PM
There is an example of point #2 when comparing WT to omicron variants in my paper if you want to know more!
www.science.org/doi/10.1126/...
Modeling the transmission mitigation impact of testing for infectious diseases
Testing effectiveness estimates the fraction by which testing and behavior can reduce transmission potential across pathogens.
www.science.org
September 18, 2025 at 2:11 PM
In general, yes! With two important caveats:
1. Tests may have different binding affinities for different variants, making them less sensitive for some
2. When you’re detectable by RDT depends on things like symptom timing and viral growth rate, which may also be different for different variants
September 18, 2025 at 2:10 PM
I wish I had done a PCR in hindsight. I just moved cities and jobs/insurance, so the idea of finding a new doc + figuring out my insurance while sick just felt daunting and potentially expensive 😅 But now I wish I tried!!
September 18, 2025 at 2:07 PM
Agreed! However, in America that still costs quite a lot of $$ depending on health insurance.
September 18, 2025 at 12:24 AM
Reports of falling fertility rates intuitively lead to speculation of reduced fertility. However, falling fertility rates could also be due to changes in reproductive behaviors leading to lower birth rates.

Is it too late to find a new term to describe women’s birth rates?
August 1, 2025 at 5:44 PM
Fertility = the ability to conceive children or young.

Fertility rate = the average number of children born to a woman over her lifetime.

Fertility is purely biological, while fertility rate depends on a combination of biological fertility and reproductive behaviors.
August 1, 2025 at 5:44 PM
!!!! Wow. The word tipping does not cross my mind to describe that hand gesture. Thank you for this.
May 28, 2025 at 10:43 PM