@marcveld.bsky.social This seems like the type of cohort/data that's (hopefully) a once in a lifetime opportunity -- really only possible to collect at-scale during a global pandemic, with a virus of low genetic diversity, with minimal-to-no preexisting immune memory in the population.

@marcveld.bsky.social Woah this is a really interesting study. I had known dormant viruses could reactivate during acute infections due to cell-stress, but had never made the connection that this could possibly be an underlying mechanism for peoples' heterogenous responses to infection

I think this is really cool #immunology work, and it's incredibly hard to study in humans! By carefully modelling their data, they were able to find that an increase in CCR2-expressing monocytes likely mediates the increase in LPS in circulation (a marker of reduced barrier integrity).

Human aging is assoc. with inflammation and intestinal barrier dysfunction. One might assume that barrier permeability would spark increased inflammation. This (and prev.) work suggests the opposite—that #inflammaging, driven by #monocytes and #macrophages appear to *cause* the barrier dysfunction!

@DrPen It's so amazing to me that federating our social networks across multiple, proprietary services is both possible AND encouraged. I have plenty of misgivings about Bluesky/Threads (and about Mastodon as well!) but in the end, this is giving us unprecedented control (at least for my […]

@marcveld.bsky.social Amazing. Following you now! Thank you :)

And share the news around to those on Bluesky! I'm so excited to have more activity now!!

@marc_veld @marcveld.bsky.social

I think you may have set it up backwards.

"marc-veld.mastodon.online.ap.brid.gy" now bridges your Mastodon account to Bluesky. To have the posts you make on Bluesky appear on Mastodon, you want to (from Bluesky) follow @ap.brid.gy

My hope for this is to finally curate a feed for myself full of #immunology #humanbiology #singlecellgenomics and #bioinformatics (as well as any/all other #academicchatter). If you end up enabling bridging, let me know!!

As far as I can tell, this seems to work well for posts published with "public" enabled. If BlueSky users interact with your post, and also have their bridge set up (same method, but by following a bot named "ap.brid.gy" instead of bsky.brid.gy), their likes & replies will be forwarded to us!!

To enable bridging of your posts to BlueSky, simply follow bsky.brid.gy@bsky.brid.gy

By following, a BlueSky account will be created by the bridging service to mirror your account. The handle will be [yourhandle]@[yourinstance].ap.brid.gy with that suffix denoting it's bridging from Activity Pub