Carman Li
@carman-mc-li.bsky.social
Assistant Professor @UPenn.bsky.social
www.CarmanLiLab.org
Hereditary cancers, BRCA1/2, mouse models, organoids, single-cell omics
www.CarmanLiLab.org
Hereditary cancers, BRCA1/2, mouse models, organoids, single-cell omics
Pinned
Carman Li
@carman-mc-li.bsky.social
· Apr 20
Carman Li Lab
www.CarmanLiLab.org
Our lab has opened at the Cancer Biology Department and the Basser Center for BRCA @upenn.bsky.social! We study new mechanisms of hereditary cancers and their implications for sporadic cancers, building on my training with @labjacks.bsky.social and Joan Brugge.
Join us! tinyurl.com/CarmanLiLabH...
Join us! tinyurl.com/CarmanLiLabH...
Thank you Andrew Olander and Shaheen @ssikandar.bsky.social for inviting me to visit the MCD Biology Department at @ucsantacruz.bsky.social! I love the insightful comments at my talk and the engaging conversations throughout. Hopefully I can come back, and maybe even get to see a real banana slug!
November 6, 2025 at 3:25 AM
Thank you Andrew Olander and Shaheen @ssikandar.bsky.social for inviting me to visit the MCD Biology Department at @ucsantacruz.bsky.social! I love the insightful comments at my talk and the engaging conversations throughout. Hopefully I can come back, and maybe even get to see a real banana slug!
We celebrated our lab’s two grant submissions with a little dessert expedition to a culinary school at West Philly! It was so good :-) Special thanks to our lab neighbor Genova for the selfie!
October 10, 2025 at 4:15 AM
We celebrated our lab’s two grant submissions with a little dessert expedition to a culinary school at West Philly! It was so good :-) Special thanks to our lab neighbor Genova for the selfie!
Our lab welcomed Isabella Cagno earlier this month. She hit the ground running, and we had a great time at the @upenn.bsky.social Cancer Biology annual retreat at beautiful Skytop, PA!
July 1, 2025 at 3:34 AM
Our lab welcomed Isabella Cagno earlier this month. She hit the ground running, and we had a great time at the @upenn.bsky.social Cancer Biology annual retreat at beautiful Skytop, PA!
Very happy to share our work at #AACR25! Thank you @theaacr.bsky.social and @bcrfcure.bsky.social for the travel award! It was fun to connect with colleagues @pennmedicine.bsky.social, @harvardmed.bsky.social, and beyond.
April 30, 2025 at 6:11 AM
Very happy to share our work at #AACR25! Thank you @theaacr.bsky.social and @bcrfcure.bsky.social for the travel award! It was fun to connect with colleagues @pennmedicine.bsky.social, @harvardmed.bsky.social, and beyond.
Our lab has opened at the Cancer Biology Department and the Basser Center for BRCA @upenn.bsky.social! We study new mechanisms of hereditary cancers and their implications for sporadic cancers, building on my training with @labjacks.bsky.social and Joan Brugge.
Join us! tinyurl.com/CarmanLiLabH...
Join us! tinyurl.com/CarmanLiLabH...
Carman Li Lab
www.CarmanLiLab.org
April 20, 2025 at 3:38 AM
Our lab has opened at the Cancer Biology Department and the Basser Center for BRCA @upenn.bsky.social! We study new mechanisms of hereditary cancers and their implications for sporadic cancers, building on my training with @labjacks.bsky.social and Joan Brugge.
Join us! tinyurl.com/CarmanLiLabH...
Join us! tinyurl.com/CarmanLiLabH...
Thank you, Camila @caoresco.bsky.social and Steven Lewis, for highlighting our work in this News & Views in Nature Genetics!
Check out our News and views on @carman-mc-li.bsky.social cool study about the molecular regulation of Brca1 deficiency mammary oncogenesis - with Steven Lewis www.nature.com/articles/s41...
Epigenetic scars of Brca1 loss point toward breast cancer cell of origin - Nature Genetics
The two-hit hypothesis suggests that a second mutation is necessary for cancer development in cells with a defective tumor-suppressor gene, such as BRCA1. However, a study now shows that the loss of j...
www.nature.com
November 20, 2024 at 9:32 PM
Thank you, Camila @caoresco.bsky.social and Steven Lewis, for highlighting our work in this News & Views in Nature Genetics!
Reposted by Carman Li
New work from Joan Brugge's lab @harvardcellbio.bsky.social explores how Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer - Led by Carman Li www.nature.com/articles/s41...
Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer - Nature Genetics
A second hit to Brca1 in heterozygous mice leads to accelerated tumor development compared to wild-type mice in which both alleles are simultaneously deleted. This is because of an epigenetic state as...
www.nature.com
November 11, 2024 at 3:16 PM
New work from Joan Brugge's lab @harvardcellbio.bsky.social explores how Brca1 haploinsufficiency promotes early tumor onset and epigenetic alterations in a mouse model of hereditary breast cancer - Led by Carman Li www.nature.com/articles/s41...