carlyschissel.bsky.social
@carlyschissel.bsky.social
Both Trp and Pro (along with Gly, Ala, Phe, Val, & Glu) worked as well! I think having something with large steric bulk next to the ester would slow the rearrangement, but these canonical residues allowed for near-full to full conversion. Thanks for asking!
February 12, 2025 at 10:53 PM