rodriguez-carleton-labs
@carleton-lab.bsky.social
Account for the Carleton and Rodriguez laboratories at the university of Geneva, Switzerland. rodriguez-carleton-labs.unige.ch
Studying claustrum and cognitive dysfunctions in neuropsychiatric disorders.
Studying claustrum and cognitive dysfunctions in neuropsychiatric disorders.
No idea but I hope someone will tell us!
November 22, 2024 at 7:54 AM
No idea but I hope someone will tell us!
Dive into our latest findings on this powerful structure here: “The claustrum is critical for maintaining working memory” biorxiv.org/cgi/content/...
The claustrum is critical for maintaining working memory information
Working memory (WM) enables the mammalian brain to temporarily store and manipulate information, supporting cognitive tasks and communication processes. Rather than depending on a single specialized a...
biorxiv.org
November 22, 2024 at 7:50 AM
Dive into our latest findings on this powerful structure here: “The claustrum is critical for maintaining working memory” biorxiv.org/cgi/content/...
💡 Our recent study suggests that the claustrum could be fundamental for maintaining working memory, supporting attention, cognitive control, and more!
November 22, 2024 at 7:50 AM
💡 Our recent study suggests that the claustrum could be fundamental for maintaining working memory, supporting attention, cognitive control, and more!
Reposted by rodriguez-carleton-labs
This work would not have been possible without the dedicated, collaborative efforts of my colleagues, Madlaina Boillat and Marie Moulinier, from the @carleton-lab.bsky.social labs. 9/9
November 19, 2024 at 7:34 AM
This work would not have been possible without the dedicated, collaborative efforts of my colleagues, Madlaina Boillat and Marie Moulinier, from the @carleton-lab.bsky.social labs. 9/9
🧩 Our findings provide a detailed cellular map of the claustro-insular region and offer new insights into how Nr4a2 regulates the molecular identity of its neurons.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A spatial single-cell atlas of the claustro-insular region uncovers key regulators of neuronal identity and excitability
The claustro-insular region is an evolutionarily conserved and extensively interconnected brain area, critical for functions such as attention, cognitive flexibility, interoception, and affective proc...
www.biorxiv.org
November 18, 2024 at 8:12 AM
🧩 Our findings provide a detailed cellular map of the claustro-insular region and offer new insights into how Nr4a2 regulates the molecular identity of its neurons.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
🔄 This shift involved activating a transcription factor cascade, resulting in altered neuronal firing patterns. This suggests NR4A2 acts as a master regulator of claustrum neuron identities and influences their functional dynamics. ⚡ #NeuronalFunction
November 18, 2024 at 8:12 AM
🔄 This shift involved activating a transcription factor cascade, resulting in altered neuronal firing patterns. This suggests NR4A2 acts as a master regulator of claustrum neuron identities and influences their functional dynamics. ⚡ #NeuronalFunction
🧠 We focused on NR4A2, a gene linked to neuropsychiatric risk and highly expressed in the claustro-insular region. Using an Nr4a2 haploinsufficiency model, we found that only claustrum neurons showed shifts in molecular identity. 🧩 #Genetics
November 18, 2024 at 8:12 AM
🧠 We focused on NR4A2, a gene linked to neuropsychiatric risk and highly expressed in the claustro-insular region. Using an Nr4a2 haploinsufficiency model, we found that only claustrum neurons showed shifts in molecular identity. 🧩 #Genetics
🧫 By combining single-cell RNA sequencing with spatial transcriptomics, we created an atlas of the claustro-insular region in mice. This approach unveiled diverse neuronal subtypes and unexpected complexity. 📊 #BrainAtlas
November 18, 2024 at 8:12 AM
🧫 By combining single-cell RNA sequencing with spatial transcriptomics, we created an atlas of the claustro-insular region in mice. This approach unveiled diverse neuronal subtypes and unexpected complexity. 📊 #BrainAtlas