Cancer Control
@cancer-control.bsky.social
Sage Publications open access journal, published in association with Moffitt Cancer Centre. Our vision is a world where gold-standard cancer care is the norm, not the exception.
Single-centre (@petermaccc.bsky.social) real-world data on #BiliaryTractCancer: 1st line gem/cis+ICI yields outcomes comparable to pivotal trials. ECOG & albumin predict survival. #HER2 amp = worse OS; dMMR & #BRCA = trend toward improved OS. Study highlights importance of molecular profiling.
November 11, 2025 at 4:00 PM
Single-centre (@petermaccc.bsky.social) real-world data on #BiliaryTractCancer: 1st line gem/cis+ICI yields outcomes comparable to pivotal trials. ECOG & albumin predict survival. #HER2 amp = worse OS; dMMR & #BRCA = trend toward improved OS. Study highlights importance of molecular profiling.
Optimistic bias related #Adherence of metastatic #BreastCancer patients to oral anticancer treatments: negative association between adherence rate and self-perception of treatment adherence. Personality matters: conscientiousness = risk awareness; extraversion = overconfidence. #Oncology
November 3, 2025 at 2:36 PM
Optimistic bias related #Adherence of metastatic #BreastCancer patients to oral anticancer treatments: negative association between adherence rate and self-perception of treatment adherence. Personality matters: conscientiousness = risk awareness; extraversion = overconfidence. #Oncology
Higher state/local social + public health spending = fewer poverty-linked cancers. Top-spending states saw ~8% lower incidence and ~9% lower mortality. Investing upstream can cut cancer burden and narrow inequities. #Oncology #PublicHealth #SDOH #CancerPrevention #HealthEquity
October 27, 2025 at 4:28 PM
Higher state/local social + public health spending = fewer poverty-linked cancers. Top-spending states saw ~8% lower incidence and ~9% lower mortality. Investing upstream can cut cancer burden and narrow inequities. #Oncology #PublicHealth #SDOH #CancerPrevention #HealthEquity
A cross-sectional survey of 198 #BreastCancer specialists across #Europe reports a strong endorsement of shared decision-making, but patchy uptake. Female physicians favour participatory styles. Digital #DecisionAids still underused compared to paper ones. #Communication #Oncology #SDM
October 17, 2025 at 3:10 PM
A cross-sectional survey of 198 #BreastCancer specialists across #Europe reports a strong endorsement of shared decision-making, but patchy uptake. Female physicians favour participatory styles. Digital #DecisionAids still underused compared to paper ones. #Communication #Oncology #SDM
Comprehensive review published in Cancer Control synthesizing #ClinicalTrials data on #OncolyticViruses (OVs) spanning 2013-2024. Provides an in-depth examination of OVs, highlighting their advancement from investigational modalities to clinical implementation. #ImmunoOncology #Virotherapy
October 7, 2025 at 12:03 PM
Comprehensive review published in Cancer Control synthesizing #ClinicalTrials data on #OncolyticViruses (OVs) spanning 2013-2024. Provides an in-depth examination of OVs, highlighting their advancement from investigational modalities to clinical implementation. #ImmunoOncology #Virotherapy
BRCA1/2-mutant early #BreastCancer: review urges region-tailored testing in Latin America, MRI-first screening, and shared surgical decision making. Neo-adjuvant platinum can raise pCR, while adjuvant olaparib improves OS. #BRCA #TNBC #PARPi #Latam
October 6, 2025 at 4:54 PM
BRCA1/2-mutant early #BreastCancer: review urges region-tailored testing in Latin America, MRI-first screening, and shared surgical decision making. Neo-adjuvant platinum can raise pCR, while adjuvant olaparib improves OS. #BRCA #TNBC #PARPi #Latam
#EarlyOnsetCRC (<50) is rising & distinct: more left-sided/advanced disease, higher MSI-H/CIMP, and unique genomic/microbiome profiles. Action: lower screening age + risk-based, noninvasive, multi-omics/microbiome-guided care.
#ColorectalCancer #CRC #Screening #PrecisionOncology
#ColorectalCancer #CRC #Screening #PrecisionOncology
September 25, 2025 at 2:38 PM
#EarlyOnsetCRC (<50) is rising & distinct: more left-sided/advanced disease, higher MSI-H/CIMP, and unique genomic/microbiome profiles. Action: lower screening age + risk-based, noninvasive, multi-omics/microbiome-guided care.
#ColorectalCancer #CRC #Screening #PrecisionOncology
#ColorectalCancer #CRC #Screening #PrecisionOncology
Oncology visits with Black patients & non-Black physicians: higher physician #ImplicitBias → more nonverbal synchrony; higher patient trust → more patient-led synchrony. Takeaway: pair bias-mitigation with workflow/communication training to strengthen equitable care. #Oncology #PatientCommunication
September 25, 2025 at 2:25 PM
Oncology visits with Black patients & non-Black physicians: higher physician #ImplicitBias → more nonverbal synchrony; higher patient trust → more patient-led synchrony. Takeaway: pair bias-mitigation with workflow/communication training to strengthen equitable care. #Oncology #PatientCommunication
Density and maturity of Tertiary Lymphoid Structures (TLS) may predict clinical outcome in invasive #LungCancer. In a 750 pt cohort, high intratumoral TLS density independently predicted better OS, while higher TLS maturation predicted worse outcomes. TLS features may sharpen risk stratification.
September 25, 2025 at 2:15 PM
Density and maturity of Tertiary Lymphoid Structures (TLS) may predict clinical outcome in invasive #LungCancer. In a 750 pt cohort, high intratumoral TLS density independently predicted better OS, while higher TLS maturation predicted worse outcomes. TLS features may sharpen risk stratification.
Analysis of #GBD2021 (204 countries) data reveals that #PancreaticCancer deaths tied to high #BMI have surged since 1990. Women still higher burden, but men rising faster, esp. ages 20–49 & low-SDI regions. #Obesity prevention + equity-focused policy needed. #GlobalHealth
September 25, 2025 at 1:44 PM
Analysis of #GBD2021 (204 countries) data reveals that #PancreaticCancer deaths tied to high #BMI have surged since 1990. Women still higher burden, but men rising faster, esp. ages 20–49 & low-SDI regions. #Obesity prevention + equity-focused policy needed. #GlobalHealth
Homelessness increases #HBV/#HCV risk. Community outreach in housing + drop-in sites linked ~2,000 Texans to care (≈2/3 needed services). Targeting engagement sites based on specific goals can help practitioners maximize outreach to high-need populations. #HealthEquity #PublicHealth
September 25, 2025 at 1:35 PM
Homelessness increases #HBV/#HCV risk. Community outreach in housing + drop-in sites linked ~2,000 Texans to care (≈2/3 needed services). Targeting engagement sites based on specific goals can help practitioners maximize outreach to high-need populations. #HealthEquity #PublicHealth
Pilot, co-designed brief decision aid for #ColorectalCancer #Screening, targeted to ages 75–85 with limited #HealthLiteracy.
20→8 pages;
understandability 44→75%, actionability 29→100%, clarity 71→~88.
Supports #SharedDecisionMaking; RCT next.
Study out in Cancer Control.
#CancerScreening #CRC
20→8 pages;
understandability 44→75%, actionability 29→100%, clarity 71→~88.
Supports #SharedDecisionMaking; RCT next.
Study out in Cancer Control.
#CancerScreening #CRC
September 19, 2025 at 1:39 PM
Pilot, co-designed brief decision aid for #ColorectalCancer #Screening, targeted to ages 75–85 with limited #HealthLiteracy.
20→8 pages;
understandability 44→75%, actionability 29→100%, clarity 71→~88.
Supports #SharedDecisionMaking; RCT next.
Study out in Cancer Control.
#CancerScreening #CRC
20→8 pages;
understandability 44→75%, actionability 29→100%, clarity 71→~88.
Supports #SharedDecisionMaking; RCT next.
Study out in Cancer Control.
#CancerScreening #CRC
A 4-week pilot in breast/colorectal cancer survivors testing continuous glucose monitoring (#CGM) + Fitbit + tailored texts was acceptable & shifted exercise readiness into action/maintenance. CGM biofeedback may help drive #PhysicalActivity; larger trials needed.
#DigitalHealth #CancerSurvivorship
#DigitalHealth #CancerSurvivorship
September 12, 2025 at 10:38 AM
A 4-week pilot in breast/colorectal cancer survivors testing continuous glucose monitoring (#CGM) + Fitbit + tailored texts was acceptable & shifted exercise readiness into action/maintenance. CGM biofeedback may help drive #PhysicalActivity; larger trials needed.
#DigitalHealth #CancerSurvivorship
#DigitalHealth #CancerSurvivorship
In a survey of 1,357 Oregonians, Asian/Pacific Islander & unemployed/disabled adults reported more negative cancer beliefs & less confidence finding trustworthy info. Study highlight need for targeted, multilingual outreach via trusted channels to boost #CancerScreening & #CancerEquity
#PublicHealth
#PublicHealth
September 3, 2025 at 3:16 PM
In a survey of 1,357 Oregonians, Asian/Pacific Islander & unemployed/disabled adults reported more negative cancer beliefs & less confidence finding trustworthy info. Study highlight need for targeted, multilingual outreach via trusted channels to boost #CancerScreening & #CancerEquity
#PublicHealth
#PublicHealth
A pre-surgery prediction model using ultrasound, routine pathology, and simple blood tests, accurately flags axillary lymph-node spread in early #BreastCancer pts. In 287 pts it showed high accuracy and real clinical utility, supporting fewer unnecessary invasive procedures.
#PrecisionOncology
#PrecisionOncology
September 3, 2025 at 2:32 PM
A pre-surgery prediction model using ultrasound, routine pathology, and simple blood tests, accurately flags axillary lymph-node spread in early #BreastCancer pts. In 287 pts it showed high accuracy and real clinical utility, supporting fewer unnecessary invasive procedures.
#PrecisionOncology
#PrecisionOncology
A routine blood score (SII) predicts patients with advanced non-small cell #LungCancer who benefit from PD-1/PD-L1 therapy. Low SII = higher response & longer PFS/OS, outperforming NLR/PLR. Data support using SII to guide selection & monitoring.
#NSCLC #Immunotherapy #Biomarkers
#NSCLC #Immunotherapy #Biomarkers
September 3, 2025 at 2:22 PM
A routine blood score (SII) predicts patients with advanced non-small cell #LungCancer who benefit from PD-1/PD-L1 therapy. Low SII = higher response & longer PFS/OS, outperforming NLR/PLR. Data support using SII to guide selection & monitoring.
#NSCLC #Immunotherapy #Biomarkers
#NSCLC #Immunotherapy #Biomarkers
Triple-mutated #AML (NPM1+FLT3-ITD+DNMT3A) is a highly aggressive subset. In 165 pts it comprised 6.7%, showed monocytic features, and had ~4-mo median survival despite similar remission. Low GNG4 expression linked to worse survival → potential prognostic #biomarker.
#Leukemia #PrecisionOncology
#Leukemia #PrecisionOncology
September 3, 2025 at 2:14 PM
Triple-mutated #AML (NPM1+FLT3-ITD+DNMT3A) is a highly aggressive subset. In 165 pts it comprised 6.7%, showed monocytic features, and had ~4-mo median survival despite similar remission. Low GNG4 expression linked to worse survival → potential prognostic #biomarker.
#Leukemia #PrecisionOncology
#Leukemia #PrecisionOncology
A simple pre-treatment blood test score (pretreatment pan-immune-inflammation value) powerfully predicted #RectalCancer patients who would respond better to neoadjuvant treatment. Patients with a low score did much better, pointing to more personalised, organ-sparing care. #Oncology #Biomarkers
September 3, 2025 at 2:02 PM
A simple pre-treatment blood test score (pretreatment pan-immune-inflammation value) powerfully predicted #RectalCancer patients who would respond better to neoadjuvant treatment. Patients with a low score did much better, pointing to more personalised, organ-sparing care. #Oncology #Biomarkers
After limb-sparing surgery for lower-extremity soft tissue #sarcoma, adjuvant conventional #radiotherapy (RT) delivered better function & #QualityOfLife than hypofractionated neoadjuvant RT, with similar oncologic control. Data support prioritizing post-op RT.
#RadiationOncology
#RadiationOncology
September 3, 2025 at 1:47 PM
After limb-sparing surgery for lower-extremity soft tissue #sarcoma, adjuvant conventional #radiotherapy (RT) delivered better function & #QualityOfLife than hypofractionated neoadjuvant RT, with similar oncologic control. Data support prioritizing post-op RT.
#RadiationOncology
#RadiationOncology
3-trial meta-analysis (n=1,254): Cabozantinib + atezolizumab didn’t improve ORR/DCR vs cabozantinib alone, but lowered several treatment-related adverse events (diarrhea, nausea, vomiting, hypokalemia). The combo may be a useful regimen for patients who cannot tolerate cabozantinib monotherapy.
August 29, 2025 at 2:09 PM
3-trial meta-analysis (n=1,254): Cabozantinib + atezolizumab didn’t improve ORR/DCR vs cabozantinib alone, but lowered several treatment-related adverse events (diarrhea, nausea, vomiting, hypokalemia). The combo may be a useful regimen for patients who cannot tolerate cabozantinib monotherapy.
Electronic health record study maps distinct comorbidity patterns in early-onset #LiverCancer. Findings support race/ethnicity-tailored screening and targeted interventions to reduce disparities.
#HealthEquity #CancerResearch #MachineLearning
#HealthEquity #CancerResearch #MachineLearning
August 28, 2025 at 12:21 PM
Electronic health record study maps distinct comorbidity patterns in early-onset #LiverCancer. Findings support race/ethnicity-tailored screening and targeted interventions to reduce disparities.
#HealthEquity #CancerResearch #MachineLearning
#HealthEquity #CancerResearch #MachineLearning
Cancer Control study in ~30k #Pennsylvania teens reveals that #HPV #Vaccination still lags after COVID. Only ~67% start by age 17. Younger cohorts start earlier, but gains have plateaued. Earlier recommendations starting at age 9 & targeted outreach may accelerate #CancerPrevention.
August 26, 2025 at 4:06 PM
Cancer Control study in ~30k #Pennsylvania teens reveals that #HPV #Vaccination still lags after COVID. Only ~67% start by age 17. Younger cohorts start earlier, but gains have plateaued. Earlier recommendations starting at age 9 & targeted outreach may accelerate #CancerPrevention.
Qualitative study in #RareCancers #Genomics surfaces 7 drivers of participant engagement and turns them into actionable communication & operations steps, helping teams boost recruitment/retention, build trust, and accelerate discovery.
#Oncology #AYAOncology #PatientEngagement #Sarcoma
#Oncology #AYAOncology #PatientEngagement #Sarcoma
August 21, 2025 at 2:36 PM
Qualitative study in #RareCancers #Genomics surfaces 7 drivers of participant engagement and turns them into actionable communication & operations steps, helping teams boost recruitment/retention, build trust, and accelerate discovery.
#Oncology #AYAOncology #PatientEngagement #Sarcoma
#Oncology #AYAOncology #PatientEngagement #Sarcoma
A recent review published in Cancer Control proposes using the 1978 Alma Ata principles to redesign global cancer care—integrating oncology into strong primary health systems to boost prevention, early detection & equity, ensuring advances reach all, regardless of geography or income.
#HealthEquity
#HealthEquity
August 15, 2025 at 12:10 PM
A recent review published in Cancer Control proposes using the 1978 Alma Ata principles to redesign global cancer care—integrating oncology into strong primary health systems to boost prevention, early detection & equity, ensuring advances reach all, regardless of geography or income.
#HealthEquity
#HealthEquity
A new Cancer Control scoping review finds optimal cancer referrals from #PrimaryCare should include detailed symptoms, relevant tests/exams, & the GP’s rationale. Clearer referrals can speed diagnosis & cut delays. #Oncology #CancerDiagnosis #EarlyDetection #HealthcareQuality #NHSEngland
August 12, 2025 at 3:00 PM
A new Cancer Control scoping review finds optimal cancer referrals from #PrimaryCare should include detailed symptoms, relevant tests/exams, & the GP’s rationale. Clearer referrals can speed diagnosis & cut delays. #Oncology #CancerDiagnosis #EarlyDetection #HealthcareQuality #NHSEngland