@canadianlongevity.bsky.social
2/2 ... increased blood vessel relaxation and reduced post-operative atrial fibrillation.
"In conclusion, short-term quercetin treatment effectively targeted vascular senescence in male CAD patients, improving inflammatory and functional outcomes."
onlinelibrary.wiley.com/doi/10.1111/...
"In conclusion, short-term quercetin treatment effectively targeted vascular senescence in male CAD patients, improving inflammatory and functional outcomes."
onlinelibrary.wiley.com/doi/10.1111/...
Quercetin Reduces Vascular Senescence and Inflammation in Symptomatic Male but Not Female Coronary Artery Disease Patients
In male patients undergoing CABG surgery, pretreatment with quercetin suppressed inflammaging and its associated inflammation, leading to improved endothelium-dependent relaxation (measured ex vivo) ...
onlinelibrary.wiley.com
May 28, 2025 at 11:17 AM
2/2 ... increased blood vessel relaxation and reduced post-operative atrial fibrillation.
"In conclusion, short-term quercetin treatment effectively targeted vascular senescence in male CAD patients, improving inflammatory and functional outcomes."
onlinelibrary.wiley.com/doi/10.1111/...
"In conclusion, short-term quercetin treatment effectively targeted vascular senescence in male CAD patients, improving inflammatory and functional outcomes."
onlinelibrary.wiley.com/doi/10.1111/...
3/3 Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease
www.aging-us.com/article/2062...
www.aging-us.com/article/2062...
Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease | Aging
Aging | doi:10.18632/aging.206227. Sultan Darvesh, Meghan K. Cash, Katrina Forrestall, Hillary Maillet, Dane Sands
www.aging-us.com
May 15, 2025 at 10:51 PM
3/3 Differential senolytic inhibition of normal versus Aβ-associated cholinesterases: implications in aging and Alzheimer’s disease
www.aging-us.com/article/2062...
www.aging-us.com/article/2062...
2/3 ... protect memory and brain health in older adults."
Nice to see more senolytic work coming out of Canada!
Senolytics target Alzheimer’s-linked brain enzymes without harming healthy ones
www.eurekalert.org/news-release...
Nice to see more senolytic work coming out of Canada!
Senolytics target Alzheimer’s-linked brain enzymes without harming healthy ones
www.eurekalert.org/news-release...
Senolytics target Alzheimer’s-linked brain enzymes without harming healthy ones
BUFFALO, NY — April 1, 2025 — A new research paper was published in Aging (Aging-US) on March 29, 2025, as the cover of Volume 17, Issue 3, titled “Differential s...
www.eurekalert.org
May 15, 2025 at 10:51 PM
2/3 ... protect memory and brain health in older adults."
Nice to see more senolytic work coming out of Canada!
Senolytics target Alzheimer’s-linked brain enzymes without harming healthy ones
www.eurekalert.org/news-release...
Nice to see more senolytic work coming out of Canada!
Senolytics target Alzheimer’s-linked brain enzymes without harming healthy ones
www.eurekalert.org/news-release...
2/2 sex-specific behavioral deficits linking TDP-43 SUMOylation with aging and disease" and that "SUMOylation is correlated with human aging and disease states".
A stress-dependent TDP-43 SUMOylation program preserves neuronal function
molecularneurodegeneration.biomedcentral.com/articles/10....
A stress-dependent TDP-43 SUMOylation program preserves neuronal function
molecularneurodegeneration.biomedcentral.com/articles/10....
A stress-dependent TDP-43 SUMOylation program preserves neuronal function - Molecular Neurodegeneration
Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are overwhelmingly linked to TDP-43 dysfunction. Mutations in TDP-43 are rare, indicating that the progressive accumulation of exo...
molecularneurodegeneration.biomedcentral.com
May 14, 2025 at 10:11 PM
2/2 sex-specific behavioral deficits linking TDP-43 SUMOylation with aging and disease" and that "SUMOylation is correlated with human aging and disease states".
A stress-dependent TDP-43 SUMOylation program preserves neuronal function
molecularneurodegeneration.biomedcentral.com/articles/10....
A stress-dependent TDP-43 SUMOylation program preserves neuronal function
molecularneurodegeneration.biomedcentral.com/articles/10....
2/2 "These results highlight SPARC as a potential therapeutic agent that would produce exercise-like effects, providing options for individuals who need exercise benefits but are unable to perform the required physical activity."
www.mdpi.com/2079-7737/14...
www.mdpi.com/2079-7737/14...
www.mdpi.com
May 12, 2025 at 8:56 PM
2/2 "These results highlight SPARC as a potential therapeutic agent that would produce exercise-like effects, providing options for individuals who need exercise benefits but are unable to perform the required physical activity."
www.mdpi.com/2079-7737/14...
www.mdpi.com/2079-7737/14...
2/2 ... the effect of PA on cerebrovascular health."
"Postmenopausal females showed greater reductions across more regions in cerebral pulsatility than other groups"
journals.sagepub.com/doi/10.1177/...
"Postmenopausal females showed greater reductions across more regions in cerebral pulsatility than other groups"
journals.sagepub.com/doi/10.1177/...
Sex-specific effects of intensity and dose of physical activity on BOLD-fMRI cerebrovascular reactivity and cerebral pulsatility - Zacharie Potvin-Jutras, Brittany Intzandt, Hanieh Mohammadi, Peiying ...
Cerebrovascular reactivity (CVR) and cerebral pulsatility (CP) are important indicators of cerebrovascular health, which are associated with physical activity (...
journals.sagepub.com
April 16, 2025 at 7:55 PM
2/2 ... the effect of PA on cerebrovascular health."
"Postmenopausal females showed greater reductions across more regions in cerebral pulsatility than other groups"
journals.sagepub.com/doi/10.1177/...
"Postmenopausal females showed greater reductions across more regions in cerebral pulsatility than other groups"
journals.sagepub.com/doi/10.1177/...
We don't have many resources yet, but hopefully our passion makes up for it!
If you would like to find out more about what we do and how you could help us on our mission, then please check out our website.
canadianlongevity.ca
If you would like to find out more about what we do and how you could help us on our mission, then please check out our website.
canadianlongevity.ca
Home - Canadian Longevity Association
Canada's Premiere Longevity Advocacy Association
canadianlongevity.ca
March 24, 2025 at 8:29 PM
We don't have many resources yet, but hopefully our passion makes up for it!
If you would like to find out more about what we do and how you could help us on our mission, then please check out our website.
canadianlongevity.ca
If you would like to find out more about what we do and how you could help us on our mission, then please check out our website.
canadianlongevity.ca
3/3 ... dietary patterns rich in plant-based foods, with moderate inclusion of healthy animal-based foods, may promote overall healthy aging and help shape future dietary guidelines."
First author Anne-Julie Tessier is from the University of Montreal.
www.nature.com/articles/s41...
First author Anne-Julie Tessier is from the University of Montreal.
www.nature.com/articles/s41...
Optimal dietary patterns for healthy aging - Nature Medicine
In two longitudinal cohorts followed for 30 years, the associations of eight different dietary patterns with healthy aging—encompassing cognitive, physical and mental health—were studied, identifying ...
www.nature.com
March 24, 2025 at 7:40 PM
3/3 ... dietary patterns rich in plant-based foods, with moderate inclusion of healthy animal-based foods, may promote overall healthy aging and help shape future dietary guidelines."
First author Anne-Julie Tessier is from the University of Montreal.
www.nature.com/articles/s41...
First author Anne-Julie Tessier is from the University of Montreal.
www.nature.com/articles/s41...
2/3 ... sticking to plant based foods with lower amounts of animal protein and especially processed foods high in salt and saturated fat, led to a 45%-86% greater chance of healthy aging.
"Our findings suggest that ...
medicalxpress.com/news/2025-03...
"Our findings suggest that ...
medicalxpress.com/news/2025-03...
Healthy eating in midlife linked to overall healthy aging
Maintaining a healthy diet rich in plant-based foods, with low to moderate intake of healthy animal-based foods and lower intake of ultra-processed foods, is linked to a higher likelihood of healthy a...
medicalxpress.com
March 24, 2025 at 7:40 PM
2/3 ... sticking to plant based foods with lower amounts of animal protein and especially processed foods high in salt and saturated fat, led to a 45%-86% greater chance of healthy aging.
"Our findings suggest that ...
medicalxpress.com/news/2025-03...
"Our findings suggest that ...
medicalxpress.com/news/2025-03...