Another nice use of multiple cohorts, including Cam-CAN

Why do some people lose memory faster with age? A mega-analysis of 13 longitudinal datasets (3,700+ adults, 10,000+ MRIs) shows that memory decline tracks brain atrophy, especially in the hippocampus, and that these links strengthen with age, but not APOE status: www.nature.com/articles/s41...

We are excited to announce #COGNESTIC 2026 @mrccbu.bsky.social in Cambridge, between 14-25 Sep 2026. Our 2-week summer school provides training in state-of-the-art methods for open neuroimaging analysis and great opportunities for professional networking:
www.mrc-cbu.cam.ac.uk/events/cogne...

Another interesting paper from LifeBrain consortium suggesting that sex differences in healthy brain aging are unlikely to explain higher prevalence of Alzheimer’s disease in women www.pnas.org/doi/10.1073/...

"CamCAN 15 years on" - a new preprint reviewing all findings about the cognitive neuroscience of ageing from sharing CamCAN data, led by @rhens.bsky.social : osf.io/preprints/ps...

New CamCAN study led by @praykov.bsky.social used 11 different white matter (WM) measures to show that WM health is multidimensional: 4 latent MRI-derived factors explained 89% of WM variance, were predicted by vascular health, and predicted cognition: doi.org/10.1038/s415...

New CamCAN paper led by @noham-wolpe.bsky.social shows that older adults’ tendency to see facial expressions as more positive may not be the adaptive “rose-coloured glasses” we thought, but could signal early cognitive decline and neurodegeneration: pubmed.ncbi.nlm.nih.gov/40854689/

International study shows that higher levels of education do not reduce rates of cognitive and brain decline in later years, contrary to views that education protects against such decline: www.nature.com/articles/s41...
@rhens.bsky.social

More fantastic work on the importance of pulse pressure from @kamentsve.bsky.social ...

Updated version of this paper now published in Cerebral Cortex 🥳 doi.org/10.1093/cerc...

@sarahhenderson.bsky.social is on a roll 🙌🏻

#PsychSciSky #neuroskyence #memory #aging

Nagrodzki et al. (@yacnag) examine attentional negativity bias in depression, linking slower processing of angry faces to increased activity in the insula, IFG, and parietal cortex. Findings suggest this bias may persist in remission: doi.org/10.1037/emo0... @APA_Journals

Temporal autocorrelation is predictive of age — out now!
www.pnas.org/doi/10.1073/...

We used @camcan-2010.bsky.social #MEG data and massive time-series feature extraction (hctsa) to understand which aspects of neural activity predict a person's age. #PNAS #aging #MEG #Neuroscience #Neuroskyence

Hello BlueSky - sorry it has taken us so long to move here from less-blue skies. Anyway please follow us if you're interested in healthy ageing of brain and cognition, including scientific outputs and news from the Cambridge Centre for Ageing and Neuroscience (www.cam-can.org).