Bunsyo Shiotani (B-Lab)
@bunsyo.bsky.social
Group leader at Tokyo Med Univ.
Replication stress response/tolerance, Genome Instability, Cancer, ATR
Replication stress response/tolerance, Genome Instability, Cancer, ATR
New PAPER alert! Led by Yano, our latest study presents how PARPi-induced heterochromatin boosts replication stress and ATRi sensitivity, revealing a new strategy for targeting SMARCA4-deficient tumors.
Link: www.nature.com/articles/s41...
Link: www.nature.com/articles/s41...
PARP inhibition-associated heterochromatin confers increased DNA replication stress and vulnerability to ATR inhibition in SMARCA4-deficient cells - Cell Death Discovery
Cell Death Discovery - PARP inhibition-associated heterochromatin confers increased DNA replication stress and vulnerability to ATR inhibition in SMARCA4-deficient cells
www.nature.com
January 29, 2025 at 6:45 AM
New PAPER alert! Led by Yano, our latest study presents how PARPi-induced heterochromatin boosts replication stress and ATRi sensitivity, revealing a new strategy for targeting SMARCA4-deficient tumors.
Link: www.nature.com/articles/s41...
Link: www.nature.com/articles/s41...