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brynnthomas.bsky.social
@brynnthomas.bsky.social
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brynnthomas.bsky.social
journals.asm.org/doi/10.1128/...
Carbapenem Activities against Pseudomonas aeruginosa: Respective Contributions of OprD and Efflux Systems | Antimicrobial Agents and Chemotherapy
ABSTRACT While meropenem MICs were strongly influenced by the presence or absence of the MexAB-OprM efflux pump in both OprD-proficient and -deficient strain backgrounds, MICs of imipenem and of ER-35...
journals.asm.org
June 11, 2025 at 5:52 PM
brynnthomas.bsky.social
bmcinfectdis.biomedcentral.com/articles/10....
Diagnostic tools for neurosyphilis: a systematic review - BMC Infectious Diseases
Purpose Increasing incidences of syphilis highlight the preoccupation with the occurrence of neurosyphilis. This study aimed to understand the current diagnostic tools and their performance to detect ...
bmcinfectdis.biomedcentral.com
June 10, 2025 at 4:53 PM
brynnthomas.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...
Potent Activity of Ertapenem Plus Cefazolin Within Staphylococcal Biofilms: A Contributing Factor in the Treatment of Methicillin-Susceptible Staphylococcus aureus Endocarditis
Besides antistaphylococcal beta-lactams and source control, there are limited validated antimicrobial salvage options in patients with prolonged methicillin-susceptible Staphylococcus aureus (MSSA) ba...
pmc.ncbi.nlm.nih.gov
June 9, 2025 at 4:49 PM
brynnthomas.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...
Potent Activity of Ertapenem Plus Cefazolin Within Staphylococcal Biofilms: A Contributing Factor in the Treatment of Methicillin-Susceptible Staphylococcus aureus Endocarditis
Besides antistaphylococcal beta-lactams and source control, there are limited validated antimicrobial salvage options in patients with prolonged methicillin-susceptible Staphylococcus aureus (MSSA) ba...
pmc.ncbi.nlm.nih.gov
June 9, 2025 at 4:46 PM
brynnthomas.bsky.social
academic.oup.com/cid/article/...
Ceftazidime/Avibactam and Ceftolozane/Tazobactam: Second-generation β-Lactam/β-Lactamase Inhibitor Combinations
Ceftolozane/tazobactam and ceftazidime/avibactam are second-generation β-lactam/β-lactamase combination antibiotics with in vitro activity against multidru
academic.oup.com
June 6, 2025 at 4:32 PM
brynnthomas.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...
Advancing therapeutics for recurrent clostridioides difficile infections: an overview of vowst’s FDA approval and implications
Clostridioides difficile infections (CDI) are a leading cause of healthcare-associated infections with a high relapse rate. Current treatment guidelines recommend fidaxomicin as the primary therapy fo...
pmc.ncbi.nlm.nih.gov
June 5, 2025 at 7:37 PM
brynnthomas.bsky.social
@juliaiburke.bsky.social
June 5, 2025 at 7:37 PM
brynnthomas.bsky.social
@juliaiburke.bsky.social @jeffpears0n.bsky.social
June 4, 2025 at 8:46 PM
brynnthomas.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...
HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem cell transplantation
HIV-1 cure remains elusive with only one reported case a decade ago1,2. Termed the “Berlin Patient”, the individual underwent 2 allogeneic Hematopoietic Stem Cell Transplantation (allo-HSCT) procedure...
pmc.ncbi.nlm.nih.gov
June 4, 2025 at 8:45 PM
brynnthomas.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...
Treatment Options for Carbapenem-Resistant Gram-Negative Infections
Rates of colonization and infection with carbapenem-resistant Gram-negative pathogens are on the rise, particularly in southeastern European countries, and this is increasingly true in Germany as well...
pmc.ncbi.nlm.nih.gov
June 3, 2025 at 7:36 PM
brynnthomas.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC....
Antimicrobial Susceptibility Testing for Enterococci
Enterococci are major, recalcitrant nosocomial pathogens with a wide repertoire of intrinsic and acquired resistance determinants and the potential of developing resistance to all clinically available...
pmc.ncbi.nlm.nih.gov
June 2, 2025 at 3:13 PM
brynnthomas.bsky.social
www.nejm.org/doi/full/10....
Fostemsavir in Adults with Multidrug-Resistant HIV-1 Infection | NEJM
Among some patients with human immunodeficiency virus type 1 (HIV-1) infection who have undergone multiple antiretroviral therapies and have limited options for treatment, new classes of antiretrov...
www.nejm.org
May 30, 2025 at 4:47 PM
brynnthomas.bsky.social
@jeffpears0n.bsky.social @juliaiburke.bsky.social
May 30, 2025 at 4:47 PM
brynnthomas.bsky.social
www.mdpi.com/2036-7449/16...
www.mdpi.com
May 29, 2025 at 5:03 PM
brynnthomas.bsky.social
pmc.ncbi.nlm.nih.gov/articles/PMC...
Survival Analysis 101: An Easy Start Guide to Analyzing Time-to-Event Data
Survival analysis, also called time-to-event analysis, is a common approach to handling event data in cardiovascular nursing and health related research. Survival analysis is used to describe, explain...
pmc.ncbi.nlm.nih.gov
May 28, 2025 at 4:26 PM