Totally agree. Trainees have a bunch of energy/enthusiasm. They often overcommit themselves to things. Having mentors advise on what to say no to is important.

It builds on a previous paper by Crass and Pai which derived an equation for vancomycin AUC dosing in obese patients. academic.oup.com/ofid/advance...

📌

It can be done but readmission and complication rates are high. pubmed.ncbi.nlm.nih.gov/33846129/

Yeah, we just two level trapezoidal pk. It really improved target attainment and AKI in our obese patients. We have a paper under review with our results.

Yeah, that would be a bargain. I’ve dropped some of them over the years. They aren’t cheap.

I don’t. My Merck contacts didn’t know.

I could go either way. I’d maybe offer a fellows project and see if they liked it.

Yeah there is a paper or two on this topic that are currently under review.

I do QID. Better exposures based on this study. pubmed.ncbi.nlm.nih.gov/30908107/

I laugh loudly to movies on planes too frequently.

They pushed the dates back for this year, but yeah the format could be updated.

Yeah, we dose adjust up all the time. Obese patients do worse (pubmed.ncbi.nlm.nih.gov/32062851/) with candidemia. Obese patients have lower exposures than normal weight patients (pubmed.ncbi.nlm.nih.gov/37272474/). There hasn’t been data that I’m aware of showing improved outcomes with higher doses

I liked lake george NY.