Bryan Duoto
bryanduoto.bsky.social
Bryan Duoto
@bryanduoto.bsky.social
"Full Stack" Biologist, NanoEngineer, and Data Scientist. Professional fish, recovering surfer, golf addict, and nature freak. Opinions are my own.
Awesome. Love to see it. It makes you a great architect, entrepreneur, and systematic problem solver.
December 23, 2024 at 5:36 AM
For me it started with immunology, branched out to stem cell bio, then chemical engineering, biochemistry, and finally AI
December 23, 2024 at 5:30 AM
We are still figuring it out! What we do know is that shape triggers different immune pathways.

Ex: spherical triggers TH1 pathway and rod-shaped triggers TH2

We've also seen that certain shapes penetrate solid tumors. We've cured several pet dogs with icosahedrons and B cells love filaments!
December 2, 2024 at 5:50 PM
The shape of a particle determines how the immune system interacts with it. Elongated or high aspect ratio shapes elicit a stronger inflammatory response compared to spherical particles of similar size.

You can basically control how matter is taken up by cells and shown as an antigen, by shape!
November 30, 2024 at 2:00 PM
I used to live in Sonoma County -- I highly recommend it 👌
November 24, 2024 at 1:22 PM