Bruce JW Evans
@brucejwevans.bsky.social
Regular posts on eye research. Visiting Professor to Optometry & Vision Sciences Dept at City St George's, University of London. From 1998-2023, Director of Research at Institute of Optometry. Currently researcher, consultant, expert witness, optometrist.
Thomas et al find that the human fovea is relatively horizontally elongated in infantile nystagmus.
pubmed.ncbi.nlm.nih.gov/41268979/
pubmed.ncbi.nlm.nih.gov/41268979/
The Human Fovea Is Relatively Horizontally Elongated in Infantile Nystagmus - PubMed
IN is associated with significant relative horizontal elongation of the anatomical fovea. These results indicate that early-onset nystagmus and foveal structure could have a direct impact on each other during development. Future work should investigate whether these differences are present at the ph …
pubmed.ncbi.nlm.nih.gov
November 23, 2025 at 11:09 AM
Thomas et al find that the human fovea is relatively horizontally elongated in infantile nystagmus.
pubmed.ncbi.nlm.nih.gov/41268979/
pubmed.ncbi.nlm.nih.gov/41268979/
Servillo et al find that laser peripheral iridotomy induces sustained angle widening in ~two-thirds of subjects, with stable long-term anatomical benefit. A thicker iris at baseline in eyes with a narrower angle predictive of persistent angle-closure despite Tx. www.aaojournal.org/article/S016...
November 16, 2025 at 10:28 AM
Servillo et al find that laser peripheral iridotomy induces sustained angle widening in ~two-thirds of subjects, with stable long-term anatomical benefit. A thicker iris at baseline in eyes with a narrower angle predictive of persistent angle-closure despite Tx. www.aaojournal.org/article/S016...
Pan et al in large study find individuals with atrial fibrillation (AF) experience a higher risk of developing both dry and wet forms of AMD compared to individuals without AF. onlinelibrary.wiley.com/doi/full/10....
Association between atrial fibrillation and age‐related macular degeneration: A multinational cohort study
Purpose To assess whether atrial fibrillation (AF) is associated with an increased risk of age-related macular degeneration (AMD). Methods This multinational retrospective cohort study included in...
onlinelibrary.wiley.com
November 16, 2025 at 10:17 AM
Pan et al in large study find individuals with atrial fibrillation (AF) experience a higher risk of developing both dry and wet forms of AMD compared to individuals without AF. onlinelibrary.wiley.com/doi/full/10....
Cheong et al find no associations between diet and myopic macular degeneration in a cohort of highly myopic adults. They state there is currently no dietary advice to prevent MMD.
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Diet and myopic macular degeneration in the Aier‐SERI high myopia adult cohort study
Purpose We investigated relationships between two dietary composite scores and myopic macular degeneration (MMD) in a high myopia adult cohort, as there is a knowledge gap regarding the role of diet...
onlinelibrary.wiley.com
November 14, 2025 at 9:30 AM
Cheong et al find no associations between diet and myopic macular degeneration in a cohort of highly myopic adults. They state there is currently no dietary advice to prevent MMD.
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Bayat et al meta-analysis finds that keratoconus pxs have atypical OCT parameters of posterior segment. They advocate OCT monitoring in keratoconus patients.
pubmed.ncbi.nlm.nih.gov/41197878/
pubmed.ncbi.nlm.nih.gov/41197878/
Structural alterations in the retina and choroid of keratoconus patients detected by optical coherence tomography: A systematic review and meta-analysis - PubMed
Keratoconus (KC) is a progressive corneal disorder that typically manifests during adolescence characterized by corneal thinning and irregularity. Recent studies have revealed that pathoanatomical abnormalities may not be limited to the anterior segment. Posterior segment alterations may also occur …
pubmed.ncbi.nlm.nih.gov
November 9, 2025 at 10:58 AM
Bayat et al meta-analysis finds that keratoconus pxs have atypical OCT parameters of posterior segment. They advocate OCT monitoring in keratoconus patients.
pubmed.ncbi.nlm.nih.gov/41197878/
pubmed.ncbi.nlm.nih.gov/41197878/
Lahoti et al note high infertility in female ophthalmologists. Cite papers showing lower infertitility in physicians than public. Theories include long work hours, high stress, occupational hazards, insomnia, physically demanding schedules, nutritional factors. pubmed.ncbi.nlm.nih.gov/41175957/
Insights into Infertility and Pregnancy among Female Ophthalmologists - PubMed
Like other female physicians in medicine, female ophthalmologists face a high infertility rate and often delay having children due to their career. Childbearing often influences fellowship, future career choices, and leadership roles. To better support female ophthalmologists who are navigating buil …
pubmed.ncbi.nlm.nih.gov
November 9, 2025 at 10:38 AM
Lahoti et al note high infertility in female ophthalmologists. Cite papers showing lower infertitility in physicians than public. Theories include long work hours, high stress, occupational hazards, insomnia, physically demanding schedules, nutritional factors. pubmed.ncbi.nlm.nih.gov/41175957/
Salvador-Roger et al evaluate a DIY approach to subjective refraction using tunable spherical & astigmatic lenses. Considered repeatable, although not fully automatic. They suggest could be a viable option if lack of eye care professionals or humanitarian works.
pubmed.ncbi.nlm.nih.gov/41100491/
pubmed.ncbi.nlm.nih.gov/41100491/
Exploring the do-it-yourself approach in subjective refraction - PubMed
The DIY approach can be considered a repeatable alternative among self-subjective refraction methods, although it is a first attempt and not yet fully automatic. While it cannot supplant traditional s...
pubmed.ncbi.nlm.nih.gov
October 19, 2025 at 12:10 PM
Salvador-Roger et al evaluate a DIY approach to subjective refraction using tunable spherical & astigmatic lenses. Considered repeatable, although not fully automatic. They suggest could be a viable option if lack of eye care professionals or humanitarian works.
pubmed.ncbi.nlm.nih.gov/41100491/
pubmed.ncbi.nlm.nih.gov/41100491/
Chen et al show that in China time outdoors prevents myopia in hyperopic children, but protection is weaker in premyopic children. Suggest longer duration of time outdoors or additional interventions to prevent or delay myopia onset in premyopes.
pubmed.ncbi.nlm.nih.gov/41062253/
pubmed.ncbi.nlm.nih.gov/41062253/
Time outdoors prevents myopia in hyperopic children, but protection is weaker in premyopic children: a post-hoc analysis of a cluster-randomised trial - PubMed
Among premyopic children, increased time outdoors has a limited protective effect on myopic shift, suggesting longer duration of time outdoors or additional interventions to prevent or delay myopia on...
pubmed.ncbi.nlm.nih.gov
October 12, 2025 at 3:23 PM
Chen et al show that in China time outdoors prevents myopia in hyperopic children, but protection is weaker in premyopic children. Suggest longer duration of time outdoors or additional interventions to prevent or delay myopia onset in premyopes.
pubmed.ncbi.nlm.nih.gov/41062253/
pubmed.ncbi.nlm.nih.gov/41062253/
Chen et al 2025 show prolonged daylight exposure, particularly during the summer, is associated with an elevated risk of POAG incidence, possibly due to increased IOP. The authors argue for protective strategies against excessive daylight exposure.
pubmed.ncbi.nlm.nih.gov/40975158/
pubmed.ncbi.nlm.nih.gov/40975158/
Association between Outdoor Daylight Exposure Duration and Primary Open-Angle Glaucoma - PubMed
Prolonged daylight exposure, particularly during the summer, is associated with an elevated risk of POAG incidence, possibly due to increased IOP. These findings highlight the need for protective stra...
pubmed.ncbi.nlm.nih.gov
October 5, 2025 at 10:31 AM
Chen et al 2025 show prolonged daylight exposure, particularly during the summer, is associated with an elevated risk of POAG incidence, possibly due to increased IOP. The authors argue for protective strategies against excessive daylight exposure.
pubmed.ncbi.nlm.nih.gov/40975158/
pubmed.ncbi.nlm.nih.gov/40975158/
Rattanalert et al 2025 look at botulinum success for treating acquire comitant esotropia in children, mean age 8y. Success rate 51%, with early treatment improving success. Suggests to me that these cases need rapid referral.
October 5, 2025 at 10:28 AM
Rattanalert et al 2025 look at botulinum success for treating acquire comitant esotropia in children, mean age 8y. Success rate 51%, with early treatment improving success. Suggests to me that these cases need rapid referral.
Systematic review & meta-analysis by Eriksen et al (2025) shows pregnancy appears to be a significant risk factor for central serous chorioretinopathy.
October 5, 2025 at 10:01 AM
Systematic review & meta-analysis by Eriksen et al (2025) shows pregnancy appears to be a significant risk factor for central serous chorioretinopathy.
Nielsen et al evaluate trends in Denmark surgery for macular hole, ERM, &floaters. Fnd variation from regions & note lack of standardised guidelines & need for RCTs on surgery for floaters. Worrying that surgery is being conducted without good evidence-base.
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Nationwide trends in macular hole, epiretinal membrane and floaters surgery, 2010–2023
Purpose
To examine the incidence of pars plana vitrectomy (PPV) for full-thickness macular hole (FTMH), epiretinal membrane (ERM) and floaters over time and across regions in Denmark.
Methods
This.....
onlinelibrary.wiley.com
September 7, 2025 at 10:06 AM
Nielsen et al evaluate trends in Denmark surgery for macular hole, ERM, &floaters. Fnd variation from regions & note lack of standardised guidelines & need for RCTs on surgery for floaters. Worrying that surgery is being conducted without good evidence-base.
onlinelibrary.wiley.com/doi/full/10....
onlinelibrary.wiley.com/doi/full/10....
Maskill & Blizzard revisit remedy from the Babylonian Talmud: mixture of scorpion & kohl for an eye condition translated as cataract. Article sugests that ancient remedies may inspire novel pharmacological strategies.
pubmed.ncbi.nlm.nih.gov/40907730/
pubmed.ncbi.nlm.nih.gov/40907730/
Scorpion Venom Peptides in Ophthalmology: Insights from the Babylonian Talmud - PubMed
Historical medical texts can reveal overlooked therapeutic approaches relevant to modern ophthalmology. This perspective revisits a remedy from the Babylonian Talmud prescribing a mixture of scorpion ...
pubmed.ncbi.nlm.nih.gov
September 7, 2025 at 9:35 AM
Maskill & Blizzard revisit remedy from the Babylonian Talmud: mixture of scorpion & kohl for an eye condition translated as cataract. Article sugests that ancient remedies may inspire novel pharmacological strategies.
pubmed.ncbi.nlm.nih.gov/40907730/
pubmed.ncbi.nlm.nih.gov/40907730/
Phu & Wang scoping review highlights link between dementia & visual field defects. Hemianopias most common, then quadrantonopia, left-sided defects more common than right.
pubmed.ncbi.nlm.nih.gov/40716026/
pubmed.ncbi.nlm.nih.gov/40716026/
Visual field defects in dementia: A scoping review - PubMed
Cross-sectional studies, case series and case reports demonstrated worse visual function and reliability indices in patients with dementia in comparison to controls. Several knowledge gaps and opportu...
pubmed.ncbi.nlm.nih.gov
August 30, 2025 at 8:24 AM
Phu & Wang scoping review highlights link between dementia & visual field defects. Hemianopias most common, then quadrantonopia, left-sided defects more common than right.
pubmed.ncbi.nlm.nih.gov/40716026/
pubmed.ncbi.nlm.nih.gov/40716026/
Sabaner et al case series of e-sports players reports pachychoroid disease, increasing risk of central serous chorioretinopathy.
pubmed.ncbi.nlm.nih.gov/40329610/
pubmed.ncbi.nlm.nih.gov/40329610/
Play, pressure, and pachychoroid: A case series on e-sports players - PubMed
PurposeThe pachychoroid disease spectrum is characterized by choroidal thickening, vascular hyperpermeability, and structural alterations in the choroidal circulation. This can lead to central serous ...
pubmed.ncbi.nlm.nih.gov
August 30, 2025 at 8:21 AM
Sabaner et al case series of e-sports players reports pachychoroid disease, increasing risk of central serous chorioretinopathy.
pubmed.ncbi.nlm.nih.gov/40329610/
pubmed.ncbi.nlm.nih.gov/40329610/
Gupta et al describe a 1y RCT comparing DIMS/HALT/CARE myopia control spectacle lenses. At 1y, DIMS and HALT perform similarly, each better than CARE. The proportion of children progressing by 0.50D or more was 5%, 7.5%, 20% in DIMS, HALT, CARE groups respectively.
pubmed.ncbi.nlm.nih.gov/40552434/
pubmed.ncbi.nlm.nih.gov/40552434/
Comparative evaluation of different (peripheral defocus based) spectacle designs in preventing myopia progression: A double-blinded randomised clinical trial - PubMed
Spectacle lenses incorporating peripheral defocus (DIMS, HALT and CARE) were all effective in reducing the rate of myopia progression significantly, with no adverse effects being observed. Among the t...
pubmed.ncbi.nlm.nih.gov
August 27, 2025 at 4:07 PM
Gupta et al describe a 1y RCT comparing DIMS/HALT/CARE myopia control spectacle lenses. At 1y, DIMS and HALT perform similarly, each better than CARE. The proportion of children progressing by 0.50D or more was 5%, 7.5%, 20% in DIMS, HALT, CARE groups respectively.
pubmed.ncbi.nlm.nih.gov/40552434/
pubmed.ncbi.nlm.nih.gov/40552434/
Abbott et al: Cochrane review finds limited evidence on lubricating drops for contact lens discomfort. Clinicians should explore lens material changes, wear schedules, care systems, environmental/behavioural factors before trying high-quality preservative-free drops
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Cochrane corner: lubricating drops for contact lens discomfort in adults - Eye
Eye - Cochrane corner: lubricating drops for contact lens discomfort in adults
www.nature.com
August 10, 2025 at 10:45 AM
Abbott et al: Cochrane review finds limited evidence on lubricating drops for contact lens discomfort. Clinicians should explore lens material changes, wear schedules, care systems, environmental/behavioural factors before trying high-quality preservative-free drops
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Yang et al highlight the bidirectional modulation of phosphorylation in chick opsins as a potential mechanism linking optical factors from induced myopia and hyperopia to the molecular signaling processes that regulate ocular growth and adaptation.
iovs.arvojournals.org/article.aspx...
iovs.arvojournals.org/article.aspx...
Bidirectional Phosphorylation Changes in Opsins Associated With Early Myopia and Hyperopia Signal Regulation by Phosphoproteomics | IOVS | ARVO Journals
iovs.arvojournals.org
August 7, 2025 at 8:53 AM
Yang et al highlight the bidirectional modulation of phosphorylation in chick opsins as a potential mechanism linking optical factors from induced myopia and hyperopia to the molecular signaling processes that regulate ocular growth and adaptation.
iovs.arvojournals.org/article.aspx...
iovs.arvojournals.org/article.aspx...
Lee et al in large population-based study show that blue-light filtering IOLs are associated with increased depressive disorders relative to clear IOL.
pubmed.ncbi.nlm.nih.gov/40738332/
pubmed.ncbi.nlm.nih.gov/40738332/
Risk of depression in persistent blue light deprivation following cataract surgery: a population-based cohort study - PubMed
The risk for depressive disorders increases for individuals with BLF IOL relative to those with clear IOL. Long-term, persistent blue light deprivation may increase risks of depression, and particular...
pubmed.ncbi.nlm.nih.gov
August 7, 2025 at 8:49 AM
Lee et al in large population-based study show that blue-light filtering IOLs are associated with increased depressive disorders relative to clear IOL.
pubmed.ncbi.nlm.nih.gov/40738332/
pubmed.ncbi.nlm.nih.gov/40738332/
Kamdar et al show that changes in cup-to-disc ratio performs similar to random selection in identifying glaucoma progression. Conclude that clinicians should gauge glaucomatous progression using both comprehensive optic nerve head examination and ancillary testing.
pubmed.ncbi.nlm.nih.gov/40653258/
pubmed.ncbi.nlm.nih.gov/40653258/
Inefficacy of Longitudinal Cup-to-Disc Ratio Measurements in Identifying Glaucoma Progression - PubMed
Longitudinal CDR data performs similar to random selection in identifying glaucoma progression on both structural and functional testing. Given this weak association, clinicians should gauge glaucomat...
pubmed.ncbi.nlm.nih.gov
July 19, 2025 at 9:26 AM
Kamdar et al show that changes in cup-to-disc ratio performs similar to random selection in identifying glaucoma progression. Conclude that clinicians should gauge glaucomatous progression using both comprehensive optic nerve head examination and ancillary testing.
pubmed.ncbi.nlm.nih.gov/40653258/
pubmed.ncbi.nlm.nih.gov/40653258/
Zhao et al find significant differences between high myopes and controls in ocular surface microbiota. They specualte that Lactobacillus vini may help mitigate myopia progression, potentially through regulating ocular surface inflammation.
pubmed.ncbi.nlm.nih.gov/40645551/
pubmed.ncbi.nlm.nih.gov/40645551/
July 19, 2025 at 9:23 AM
Zhao et al find significant differences between high myopes and controls in ocular surface microbiota. They specualte that Lactobacillus vini may help mitigate myopia progression, potentially through regulating ocular surface inflammation.
pubmed.ncbi.nlm.nih.gov/40645551/
pubmed.ncbi.nlm.nih.gov/40645551/
Flitcroft et al in new IMI paper clarify difference between Myopia Management (basically, comprehensive term for all clinical activities to do with myopia) & myopia control (evidence based slowing of myopia progression/axial elongation).
pubmed.ncbi.nlm.nih.gov/40504524/
pubmed.ncbi.nlm.nih.gov/40504524/
June 15, 2025 at 5:10 PM
Flitcroft et al in new IMI paper clarify difference between Myopia Management (basically, comprehensive term for all clinical activities to do with myopia) & myopia control (evidence based slowing of myopia progression/axial elongation).
pubmed.ncbi.nlm.nih.gov/40504524/
pubmed.ncbi.nlm.nih.gov/40504524/
Dong et al report in large study in Wuhu, China, further increase in myopia. 92% of high school students myopic and, alarmingly, 19% have high myopia. Only 48% of myopic individuals are using vision correction.
pubmed.ncbi.nlm.nih.gov/40492984/
pubmed.ncbi.nlm.nih.gov/40492984/
Prevalence of Myopia and Axial Length Distribution in China: The Wuhu Children and Adolescents Eye Study - PubMed
Compared with previous studies, the present investigation suggests a further rise in the prevalence of myopia, particularly high myopia, in the younger generations in China.
pubmed.ncbi.nlm.nih.gov
June 15, 2025 at 8:52 AM
Dong et al report in large study in Wuhu, China, further increase in myopia. 92% of high school students myopic and, alarmingly, 19% have high myopia. Only 48% of myopic individuals are using vision correction.
pubmed.ncbi.nlm.nih.gov/40492984/
pubmed.ncbi.nlm.nih.gov/40492984/
Redondo et al show in computer vision syndrome that frequent breaks improved accommodative variability and reduced near-work induced transient myopia.
pubmed.ncbi.nlm.nih.gov/40466853/
pubmed.ncbi.nlm.nih.gov/40466853/
The impact of break schedules on digital eye strain symptoms and ocular accommodation during prolonged near work - PubMed
This study evaluated the effects of four different break schedules on symptoms and signs of Digital Eye Strain (DES) during a 40-min reading task. Twenty-four young adults participated in four experim...
pubmed.ncbi.nlm.nih.gov
June 9, 2025 at 3:59 PM
Redondo et al show in computer vision syndrome that frequent breaks improved accommodative variability and reduced near-work induced transient myopia.
pubmed.ncbi.nlm.nih.gov/40466853/
pubmed.ncbi.nlm.nih.gov/40466853/