Bronwyn Lucas
@bronwynalucas.bsky.social
Asst Prof of Molecular Cell Biology and Computational Biology at UC Berkeley
Building a new lab capturing close-ups of cells with electrons. lucaslab.science
Attempting to "dwell (somewhat) patiently in the variety and complexity of organisms."
Building a new lab capturing close-ups of cells with electrons. lucaslab.science
Attempting to "dwell (somewhat) patiently in the variety and complexity of organisms."
It makes sense to me that this would work. Nice Oli
September 19, 2025 at 9:13 PM
It makes sense to me that this would work. Nice Oli
This would be huge.
September 10, 2025 at 3:42 AM
This would be huge.
Welcome to California! Are you stopping by Berkeley while you are here?
September 9, 2025 at 3:38 PM
Welcome to California! Are you stopping by Berkeley while you are here?
Reposted by Bronwyn Lucas
Special mention to @joshdcryoem.bsky.social and Matthew Giammar who have become driving forces within the project - I'm excited to see community driven open source flourish in cryo-EM, let's see where things go! 🥰
August 30, 2025 at 2:06 AM
Special mention to @joshdcryoem.bsky.social and Matthew Giammar who have become driving forces within the project - I'm excited to see community driven open source flourish in cryo-EM, let's see where things go! 🥰
@lainahall.bsky.social contributed lamellae and images. Keep an eye out for more from her in the not to distant future
August 30, 2025 at 2:11 AM
@lainahall.bsky.social contributed lamellae and images. Keep an eye out for more from her in the not to distant future
This work exists as part of a broader ecosystem of modular tools in the cryo-EM community with the goal of making it easy for new users and developers to customize for their specific application. Especially in the early days of in situ structural biology, rapid iteration is important!
August 30, 2025 at 12:57 AM
This work exists as part of a broader ecosystem of modular tools in the cryo-EM community with the goal of making it easy for new users and developers to customize for their specific application. Especially in the early days of in situ structural biology, rapid iteration is important!
@joshdcryoem.bsky.social got us connected with #teamtomo, worked alongside Matthew to contribute to the code, built the simulator and adapted Leopard-EM to perform pixel size optimization and constrained search.
August 30, 2025 at 12:53 AM
@joshdcryoem.bsky.social got us connected with #teamtomo, worked alongside Matthew to contribute to the code, built the simulator and adapted Leopard-EM to perform pixel size optimization and constrained search.
This project was driven by Comp Bio PhD student Matthew Giammar who designed the structure and wrote most of the code. He separated the core functions from the user facing programs to make it easy to build new functionality with minimal changes to the user interface.
August 30, 2025 at 12:51 AM
This project was driven by Comp Bio PhD student Matthew Giammar who designed the structure and wrote most of the code. He separated the core functions from the user facing programs to make it easy to build new functionality with minimal changes to the user interface.
Congratulations Francis!!
August 7, 2025 at 4:43 PM
Congratulations Francis!!
Reposted by Bronwyn Lucas
If you are going to M&M, also see postdoc @joshdcryoem.bsky.social's poster about tilted vs untilted data collection for in situ structural biology www.sciencedirect.com/science/arti....
To tilt or not to tilt? Strategies for in situ cryo-EM data collection
Recent breakthroughs in single-particle cryogenic electron microscopy (cryo-EM) and protein structure prediction have transformed our ability to resol…
www.sciencedirect.com
July 25, 2025 at 8:08 PM
If you are going to M&M, also see postdoc @joshdcryoem.bsky.social's poster about tilted vs untilted data collection for in situ structural biology www.sciencedirect.com/science/arti....
Reposted by Bronwyn Lucas
PhD student @lainahall.bsky.social will be giving a talk about our measurements of FIB-milling damage in cryo-lamellae (with new data!) at M&M on Tuesday next week.
July 25, 2025 at 8:04 PM
PhD student @lainahall.bsky.social will be giving a talk about our measurements of FIB-milling damage in cryo-lamellae (with new data!) at M&M on Tuesday next week.
@joshdcryoem.bsky.social will also be giving a talk about his prior work as a PhD student with Chris Russo developing strategies to take advantage of the reduced radiation damage at liquid Helium temperatures for cryo-EM. You can find their paper here: www.pnas.org/doi/abs/10.1...
Reducing the effects of radiation damage in cryo-EM using liquid helium temperatures | PNAS
The physical limit in determining the atomic structure of biological molecules is
radiation damage. In electron cryomicroscopy, there have been num...
www.pnas.org
July 25, 2025 at 8:12 PM
@joshdcryoem.bsky.social will also be giving a talk about his prior work as a PhD student with Chris Russo developing strategies to take advantage of the reduced radiation damage at liquid Helium temperatures for cryo-EM. You can find their paper here: www.pnas.org/doi/abs/10.1...
If you are going to M&M, also see postdoc @joshdcryoem.bsky.social's poster about tilted vs untilted data collection for in situ structural biology www.sciencedirect.com/science/arti....
To tilt or not to tilt? Strategies for in situ cryo-EM data collection
Recent breakthroughs in single-particle cryogenic electron microscopy (cryo-EM) and protein structure prediction have transformed our ability to resol…
www.sciencedirect.com
July 25, 2025 at 8:08 PM
If you are going to M&M, also see postdoc @joshdcryoem.bsky.social's poster about tilted vs untilted data collection for in situ structural biology www.sciencedirect.com/science/arti....
PhD student @lainahall.bsky.social will be giving a talk about our measurements of FIB-milling damage in cryo-lamellae (with new data!) at M&M on Tuesday next week.
July 25, 2025 at 8:04 PM
PhD student @lainahall.bsky.social will be giving a talk about our measurements of FIB-milling damage in cryo-lamellae (with new data!) at M&M on Tuesday next week.