Read more: www.gov.uk/government/n...

👉 Partnering on efforts to develop quantum computers and "open new avenues to use AI in targeted treatments which can aid drug discovery" in "a fraction of the time and cost it takes today." 🧵

👉 Accelerating "world-leading AI research to help develop new drugs, faster life-saving treatments and improved cancer care." 🧵

▪️ We need to find common ground. It starts by recognizing that we won’t agree on every issue, he said. We just need to agree on a few critical issues and start from there.

👉 Watch the full conversation here: www.youtube.com/watch?v=BIBC...

▪️ There is still a great American story. It’s the story of Whitman, and Thoreau, and King, he said. We are unpretentious. There is no aristocracy. No one is below us and no one is above us. We take responsibility for ourselves and for one another. 🧵

▪️ We have to decide what we believe in and defend it. When he was President, people could be wealthy and progressive, he said, and weren't called upon to defend their positions. Now, universities, law firms, and businesses must be willing to push back even when it’s uncomfortable. 🧵

▪️ Social media has become a tool for sowing discord. It appeals to our basest instincts, and allows everyone to see what they can’t have. It drives feelings of alienation and anger that have been stoked further by those who benefit from that discord. What if, instead, it were a tool for good? 🧵

▪️ Facts matter. People in power around the world are deliberately sowing confusion, eroding our trust, so that we no longer no what to believe – or no longer believe anything. Agreeing on certain fundamental facts is critical to rebuilding the foundation where progress is possible. 🧵

5️⃣ The YODA (Yale University Open Data Access) Project: Companies like Johnson & Johnson partner with YODA to make anonymized clinical trial data available to external researchers – fostering secondary analysis & new discoveries from existing trial data. yoda.yale.edu

#openscience #discovery

4️⃣ @recursionpharma.bsky.social's Open-Science Data & Tools: Recursion provides open source datasets to accelerate AI drug discovery research. RxRx1 (100,000+ cell images); RxRx3 (100 Tb dataset of 17,000+ genes & 2+ million cell images) & RxRx3-core (18Gb). Plus: foundation models. www.rxrx.ai 🧵

3️⃣ The Structural Genomics Consortium: A major global public-private open science effort which includes a number of pharma companies. They’ve determined 4k+ protein structures - placed in the public domain - & developed chemical probes for understudied protein families. www.thesgc.org 🧵

2️⃣ Boehringer Ingelheim’s opnME: BI’s open science portal provides free access to molecules to the scientific community (over 9,000 delivered so far) as well as funding and collaboration opportunities. www.opnme.com 🧵

1️⃣ Allen Institute’s Open Science Tools: Their open data portals includes the Allen Brain Map - neuroscience reference atlases, cell type data & modeling tools; & Allen Cell Explorer – cell biology resources, hiPSC lines, plasmids, imaging software & 3D models. alleninstitute.org/open-science... 🧵

He says: “What can be more human than wanting to use all of our knowledge, all of our effort, all of our resources, to try to make the lives of our kids safer and better than our own lives? A huge part of that aspiration requires, & is indeed driven by, science.” www.theguardian.com/science/2025...

As one of many prominent researchers at Harvard – which has just had all of its federal research funding halted – Liu has been vocal about the disastrous impact of cutting research. 🧵

By 2019, they released prime editing in another Nature paper, “a less efficient but more powerful technique that in principle can repair nearly all disease-causing mutations.” Now, base editing & prime editing are being used in more than a dozen clinical trials. www.nature.com/articles/s41... 🧵

But once his focus turned to fixing genes, he never looked back. His team first published on base editing – using CRISPR guide molecules to change single-letter mutations in the genetic code (which account for nearly 1/3 of genetic diseases) in Nature in 2016. www.nature.com/articles/nat.... 🧵