Brian Shim
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brianhshim.bsky.social
Brian Shim
@brianhshim.bsky.social
PhD candidate in David Liu’s lab at Harvard and Broad Institute. Applying gene editing, targeted delivery, and protein evolution to develop new immunotherapies.
Reposted by Brian Shim
Excited to introduce evoCAST: a platform for efficient, programmable gene integration in human cells. This work, a close collab between my PhD lab (Liu group) and @sternberglab.bsky.social, has been such a fun journey to help lead. Huge thanks to all contributors!

www.science.org/doi/10.1126/...
Programmable gene insertion in human cells with a laboratory-evolved CRISPR-associated transposase
Programmable gene integration in human cells has the potential to enable mutation-agnostic treatments for loss-of-function genetic diseases and facilitate many applications in the life sciences. CRISP...
www.science.org
May 15, 2025 at 7:06 PM
Reposted by Brian Shim
Anyone who is anti-vax is pro-death. Period. The science and data do not lie. And they don’t care about your podcast.
November 24, 2024 at 10:52 PM