Brian Kraemer
@brianckraemer.bsky.social
Father
Husband
Dementia Neuroscientist, Classical Geneticist
Outdoor Enthusiast
Opinions are my own.
https://kraemerlab.uw.edu/
Husband
Dementia Neuroscientist, Classical Geneticist
Outdoor Enthusiast
Opinions are my own.
https://kraemerlab.uw.edu/
Here's a nice review from Rosa Rademakers & Co if you want to learn more about human TMEM106b proteinopathies. pubmed.ncbi.nlm.nih.gov/36056242/
Identification of TMEM106B amyloid fibrils provides an updated view of TMEM106B biology in health and disease - PubMed
Since the initial identification of TMEM106B as a risk factor for frontotemporal lobar degeneration (FTLD), multiple genetic studies have found TMEM106B variants to modulate disease risk in a variety ...
pubmed.ncbi.nlm.nih.gov
January 2, 2025 at 9:01 PM
Here's a nice review from Rosa Rademakers & Co if you want to learn more about human TMEM106b proteinopathies. pubmed.ncbi.nlm.nih.gov/36056242/
For those of you that haven't heard about it, TMEM106b is an important risk factor for a variety of neurodegenerative diseases. It was first shown as a risk factor for FTLD-TDP by Viviana VanDeerlin & Co more than a decade ago. More recently, it has been show to form fibrils in these diseases.
January 2, 2025 at 9:00 PM
For those of you that haven't heard about it, TMEM106b is an important risk factor for a variety of neurodegenerative diseases. It was first shown as a risk factor for FTLD-TDP by Viviana VanDeerlin & Co more than a decade ago. More recently, it has been show to form fibrils in these diseases.