Brent Richards
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brent-richards.bsky.social
Brent Richards
@brent-richards.bsky.social
Endocrinologist, geneticist and entrepreneur just trying to help my patients. Prof at McGill and CEO of 5Prime Sciences
There are few more engaging, creative and relentless clinician scientists than @stephenorahilly.bsky.social

I enjoyed his visit to @mcgilluniversity.bsky.social and learning how he unpicked GDF15 as a cause of morning sickness.
April 10, 2025 at 6:27 PM
And Kevin Liang successfully defended his PhD examining the use of human genetics to identify drug targets!

Well done Dr. Kevin
March 25, 2025 at 1:24 PM
An excellent visit from @mendelrandom.bsky.social in Montreal this week.

He wants to change Mendelian randomization to "meiotic randomization"—likely a much better name.

But what would we call @mendelrandom.bsky.social ?
March 14, 2025 at 3:33 PM
Taken together, this provides evidence that increased endotrophin levels is one reason that people with obesity have more heart attacks.

This provides a target to help people with obesity reduce their risks of disease.
January 26, 2025 at 9:08 PM
We identified that endotrophin was one such protein.

Using genetically-determined endotrophin levels we shows that endotrophin causes CHD.

To do so, we needed to use "protein domain-aware" methods since endotrophin is a cleaved protein from COL6A3.
January 26, 2025 at 9:08 PM