Brady Spencer
bradyspencer12.bsky.social
Brady Spencer
@bradyspencer12.bsky.social
Postdoc in @Kdoranlab at CU-Anschutz studying host-strep interactions | she/her 🏔🦮🔬🎼☕️
Reposted by Brady Spencer
The staphylococcal type VII secretion system impacts daptomycin sensitivity through controlling bacterial cell envelope integrity https://www.biorxiv.org/content/10.1101/2023.11.20.567842v1
The staphylococcal type VII secretion system impacts daptomycin sensitivity through controlling bacterial cell envelope integrity https://www.biorxiv.org/content/10.1101/2023.11.20.567842v1
The Staphylococcus aureus type VII secretion system (T7SS) plays an important role in bacterial viru
www.biorxiv.org
November 21, 2023 at 3:18 AM
Reposted by Brady Spencer
Letter to the editor "Finding umbrella trees: cultivating inclusion and more than survival in a post-affirmative action academy" by Beronda L. Montgomery/@BerondaM now available in corrected proof stage.

Check it out!
October 26, 2023 at 10:33 PM
Reposted by Brady Spencer
Welcome to Day 2 of Black In Microbiology Week 2023. This morning we are amplifying Black In Micro early career researchers! Dr. Ninecia Scott is here to get us started: youtu.be/gR0m18USQak...

Thanks to KathASK Films for making this video possible
Research Day - Black in Micro Week 2023
youtu.be
October 24, 2023 at 12:23 PM
Reposted by Brady Spencer
#BIMRollCall

Hello! My name is Kishana Taylor and I am a virologist who studies zoonotic viruses with a special interest in vector-borne (spread by insects) viruses. I’m also @blackinmicro.bsky.social president.
October 23, 2023 at 10:47 PM
Reposted by Brady Spencer
As it’s #BlackinMicro Week let me reintroduce myself:

Hi!! 👋🏾 I am Aisha and a 5th year post doc at the NIH and will be transitioning to Assistant Research Professor of Microbiology at Cornell starting Jan. 1st. My research looks at how small proteins help regulate bacterial stress responses.
October 23, 2023 at 1:36 PM
Reposted by Brady Spencer
Available now: UPDATED flyer showing our full #BlackInMicrobiology Week 2023 schedule! We can't wait to kick things off on Monday and celebrate with you, please see our corrected time for the STEM education panel.

Register or Learn more today: blackinmicrobiology....
October 21, 2023 at 6:16 PM
Reposted by Brady Spencer
Streptococcus agalactiae and Escherichia coli Induce Distinct Effector γδ T Cell Responses During Neonatal Sepsis and Neuroinflammation https://www.biorxiv.org/content/10.1101/2023.10.02.560561v1
Streptococcus agalactiae and Escherichia coli Induce Distinct Effector γδ T Cell Responses During Neonatal Sepsis and Neuroinflammation https://www.biorxiv.org/content/10.1101/2023.10.02.560561v1
The neonatal phase of life is a time during which susceptibility to infection is particularly high,
www.biorxiv.org
October 4, 2023 at 12:16 AM
Reposted by Brady Spencer
On a different note, a cool paper: www.science.org/doi/10.1126/...

The hygiene hypothesis has been a major idea floating for a long time. New study shows mice exposed to a more wild microbiome still develop allergies just the same.

What does diverse #Microbiome 🦠 actually mean?

#Immunology
Laboratory mice with a wild microbiota generate strong allergic immune responses
Allergen exposure in wildling mice induces robust de novo responses and activates an endogenous memory TH2 cell pool.
www.science.org
September 30, 2023 at 2:13 PM
Reposted by Brady Spencer
Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection

-in Cell Host & Microbe

www.sciencedirect.com/science/arti...
September 30, 2023 at 2:50 PM
Reposted by Brady Spencer
Toxin-mediated depletion of nicotinamide dinucleotides drives persister formation in a human pathogen https://www.biorxiv.org/content/10.1101/2023.09.28.559889v1
Toxin-mediated depletion of nicotinamide dinucleotides drives persister formation in a human pathogen https://www.biorxiv.org/content/10.1101/2023.09.28.559889v1
Toxin-antitoxin (TA) systems are widespread in bacteria and are implicated in genome stability, viru
www.biorxiv.org
September 30, 2023 at 4:17 AM
Reposted by Brady Spencer
Reversible conjugation of a CBASS nucleotide cyclase regulates immune response to phage infection https://www.biorxiv.org/content/10.1101/2023.09.29.560134v1
Reversible conjugation of a CBASS nucleotide cyclase regulates immune response to phage infection https://www.biorxiv.org/content/10.1101/2023.09.29.560134v1
Antiviral defence systems build the prokaryotic immune system and their proper regulation is vital f
www.biorxiv.org
September 30, 2023 at 4:19 AM
Reposted by Brady Spencer
My lab's first big research paper is now out in mBio! 🎉
We ask: how can Legionella antagonize other microbes with reactive oxygen species without hurting themselves? Answer: several dynamics seem to generate a 'toxic moat' of ROS around producers
pubmed.ncbi.nlm.nih.gov/37728338/
September 25, 2023 at 9:26 PM
Reposted by Brady Spencer
Whoo hoo! It’s out!
The alternative sigma factor SigN of Bacillus subtilis is intrinsically toxic

J Bacteriology by Aisha Burton et al from Dan Kearns lab
with Libor Krásný lab

journals.asm.org/doi/10.1128/...
September 21, 2023 at 6:06 PM
Reposted by Brady Spencer
Microbiologists, as requested we have a feed: MicroSky! Use this form to sign up: docs.google.com/forms/d/e/1F... and then tag posts with #MicroSky (case insensitive) or 🧫 or 🦠 and enjoy! Thanks to @kyt-thatsme.bsky.social and @jmarsh.bsky.social for getting this going
September 13, 2023 at 1:15 AM
Reposted by Brady Spencer
Streptococcus mutans inhibits the growth of Enterococcus via the non-ribosomal cyclic peptide mutanobactin https://www.biorxiv.org/content/10.1101/2023.09.12.557362v1
Streptococcus mutans inhibits the growth of Enterococcus via the non-ribosomal cyclic peptide mutanobactin https://www.biorxiv.org/content/10.1101/2023.09.12.557362v1
Enterococcus faecalis is a Gram-positive commensal bacterium in the gastrointestinal tract and an op
www.biorxiv.org
September 13, 2023 at 3:17 AM
Reposted by Brady Spencer
Diet influences community dynamics following vaginal group B Streptococcus colonization https://www.biorxiv.org/content/10.1101/2023.09.10.556920v1
Diet influences community dynamics following vaginal group B Streptococcus colonization https://www.biorxiv.org/content/10.1101/2023.09.10.556920v1
The vaginal microbiota plays a pivotal role in reproductive, sexual, and perinatal health and diseas
www.biorxiv.org
September 11, 2023 at 3:16 AM