Kaan Boztug
boztugk.bsky.social
Kaan Boztug
@boztugk.bsky.social
Reposted by Kaan Boztug
🚨 Open #position! The Clinic of Pediatric Immunology and Rheumatology at the University Hospital #Bonn is looking for a

Oberärztin*arzt (m/w/d)

Check out the full job ad at our website (German): www.immunosensation.de/opportunitie...

@boztugk.bsky.social #jobalert #immunology #rheumatology
May 13, 2025 at 1:35 PM
Reposted by Kaan Boztug
🚨 #Hiring now! The group of @boztugk.bsky.social from the newly found Clinic of Pediatric Immunology and Rheumatology is looking for a

Postdoc: Mechanisms of autoimmunity and autoinflammation in inborn errors of immunity (m/f/d)

Go to our website: www.immunosensation.de/opportunitie...
May 15, 2025 at 10:48 AM
Reposted by Kaan Boztug
🚨 Open #position! The group of @boztugk.bsky.social from the newly found Clinic of Pediatric Immunology and Rheumatology is looking for a

PhD in immunobiology of selected inborn errors of immunity (m/f/d)

You can find the job ad at our website: www.immunosensation.de/opportunitie...
May 15, 2025 at 10:52 AM
Reposted by Kaan Boztug
🔬 New #EquationsForLife! @boztugk.bsky.social‬’s group uses the #LotkaVolterra model to study immune cell-antigen dynamics. Genetic mutations can disrupt this balance & cause #IEIs, leading to disease. Their research explores how targeted therapies can restore it.
🔎 tinyurl.com/CeMMRR2024-B...
May 20, 2025 at 7:24 AM
Reposted by Kaan Boztug
Also off for a great start of day 2:
Albert Wiegman, Amsterdam on the fascinating and important efforts for early detection of a rare disease: Familial hypercholesterolemia
December 3, 2024 at 8:25 AM
Thanks Alex! So happy to have you as Keynote Speaker tomorrow!
Stunning first session - Cancer and Precision Oncology!
Amazing invited talks by Stefan Pfister, Stefan Fröhling, Shahrokh Shariat and Sally George - great choice @boztugk.bsky.social! Followed by superb abstract selected talks.
December 2, 2024 at 8:41 PM
Reposted by Kaan Boztug
💡 Newly found genetic defect! In their study published in Science Immunology, @boztugk.bsky.social and @bernhard-ransmayr.bsky.social describe how LTBR-mutations disrupt secondary lymphoid organs, causing severe Immune Deficiencies (IEI). 🔗 tinyurl.com/57mmv5v7
November 25, 2024 at 9:02 AM
Reposted by Kaan Boztug
New in #ScienceImmunology:

Research from @boztugk.bsky.social and team identifies an inborn error of #immunity caused by human LTβR deficiency, resulting in defective stromal cell signaling and impaired humoral immune responses.

Read more: www.science.org/doi/10.1126/...
LTβR deficiency causes lymph node aplasia and impaired B cell differentiation
Loss-of-function mutations in LTBR result in a stromal defect, leading to dysfunctional secondary lymphoid organs and combined immunodeficiency in humans.
www.science.org
November 23, 2024 at 8:53 AM
Please see our discovery on molecular dissection of a novel inborn error of immunity, caused by LOF mutations affecting LTBR. Congratulations to our PhD Student and first author @bernhard-ransmayr.bsky.social! Thank you to all the fantastic collaboration partners! @stanna-ccri.bsky.social
Happy to announce the publication of our paper in Science Immunology. Here we describe the first patients with biallelic disease causing mutations in the LTBR gene encoding for the lymphotoxin beta receptor. 1/10
www.science.org/doi/10.1126/...
LTβR deficiency causes lymph node aplasia and impaired B cell differentiation
Loss-of-function mutations in LTBR result in a stromal defect, leading to dysfunctional secondary lymphoid organs and combined immunodeficiency in humans.
www.science.org
November 25, 2024 at 12:32 PM