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bourboulialab.bsky.social
@bourboulialab.bsky.social
Reposted
Just out in Journal of Biological Chemistry!
Our latest paper uses deep learning to dissect PTM crosstalk on Hsp90 and its role in drug binding.
Proud of this team effort! www.jbc.org/article/S002...
Integrating deep learning for post-translational modifications crosstalk on Hsp90 and drug binding
Post-translational modification (PTM) of proteins regulates cellular proteostasis by expanding protein functional diversity. This naturally leads to increased proteome complexity as the result of PTM ...
www.jbc.org
July 29, 2025 at 5:19 PM
Reposted
📢 Our October issue is now online. Access the full issue 👉 www.cell.com/trends/bioch....

🎨 The cover highlights a Review from @chiosislabmskcc.bsky.social‬ and co on how PTMs reprogram chaperones into epichaperomes.
October 6, 2025 at 2:40 PM