@straversallard.bsky.social, Stéphanie Baron, David Penton Ribas, @fabiofrosa.bsky.social, Maria-Christina Zennaro
@straversallard.bsky.social, Stéphanie Baron, David Penton Ribas, @fabiofrosa.bsky.social, Maria-Christina Zennaro
Thank you to all the co-authors and collaborators !
Bakhta Fedlaoui, Teresa Cosentino, Zeina Al Sayed, Rita Alexandre Coelho, Isabelle Giscos-Douriez, Nicolò Faedda, @mayfayad.bsky.social, Jean-Sébastien Hulot, Chris Magnus, Scott Sternson
Thank you to all the co-authors and collaborators !
Bakhta Fedlaoui, Teresa Cosentino, Zeina Al Sayed, Rita Alexandre Coelho, Isabelle Giscos-Douriez, Nicolò Faedda, @mayfayad.bsky.social, Jean-Sébastien Hulot, Chris Magnus, Scott Sternson
Applying this chemogenetic approach could also enable the development of a new inducible mouse model of primary aldosteronism, providing a valuable tool for dissecting the mechanisms underlying aldosterone producing adenoma development and for evaluating new therapeutic strategies.
Applying this chemogenetic approach could also enable the development of a new inducible mouse model of primary aldosteronism, providing a valuable tool for dissecting the mechanisms underlying aldosterone producing adenoma development and for evaluating new therapeutic strategies.
This innovative model could be used to test the molecular impact of new treatments for primary aldosteronism in vitro.
This innovative model could be used to test the molecular impact of new treatments for primary aldosteronism in vitro.
We demonstrated that increased expression of CYP11B2 and stimulation of the mineralocorticoid biosynthesis pathway are associated with a decrease of cell proliferation and an increase of apoptosis, indicating that additional events may be required for the development of APA.
We demonstrated that increased expression of CYP11B2 and stimulation of the mineralocorticoid biosynthesis pathway are associated with a decrease of cell proliferation and an increase of apoptosis, indicating that additional events may be required for the development of APA.
We demonstrated that increased expression of CYP11B2 and stimulation of the mineralocorticoid biosynthesis pathway are associated with a decrease of cell proliferation and an increase of apoptosis, indicating that additional events may be required for the development of APA.
We demonstrated that increased expression of CYP11B2 and stimulation of the mineralocorticoid biosynthesis pathway are associated with a decrease of cell proliferation and an increase of apoptosis, indicating that additional events may be required for the development of APA.
Je decouvre
Je decouvre