New preprint ↙️

Using 2 independent 7T fMRI datasets (HCP & our PNI dataset 🧲 💅 ), we found that intersubject synchronization 👯 during movies aligns closely with cortical gradients 🌈, especially along the visual-to-transmodal axis

by Meaghan Smith & a terrific team ↙️
doi.org/10.1101/2025...

🚨 New paper in Nature Methods:
HippoMaps: multiscale cartography of the human hippocampus

Open-source tools & data to explore structure and function of the 🍤🧠 (histology, in/ex vivo MRI, iEEG)

Led by @jordandekraker.bsky.social

docs: hippomaps.readthedocs.io
paper: doi.org/10.1038/s415...

New paper🥳

🧠 In TLE, brain changes go beyond the temporal lobe & beyond normal aging.

Our ENIGMA study (769 patients, 18 sites) found widespread gray & white matter decline, especially after 55. By Judy Chen and a terrific intl' team

Time for earlier diagnosis & deeper research
bit.ly/3HRYeQt

🎉 New paper in press at @epilepsiajournal.bsky.social

"MRI-negative epilepsy: A systematic review and meta-analysis" led by Ravnoor Gill et al.

We highlight ambiguities in the term "MRI-negative" & stress better imaging and analysis to improve epilepsy care

👉 doi.org/10.1111/epi....

News from ENIGMA-Epilepsy! 🧠

Our latest study links polygenic risk for TLE-HS to cortical thinning in kids—mirroring patterns in adult patients.

Early imaging-genetics insights could reveal interplay of epilepsy risk and phenotypes before symptoms emerge.

Read more 👉 doi.org/10.1093/brai...

The Neuro (aka MNI) is looking for a new director

Key priorities for this exciting/challenging position are to sustain & enhance excellence in:
🧠 neurosciences research & teaching;
🧠 clinical care;
🧠 & to boost provincial, national, and international profile

More info & apply here:
bit.ly/3SZvnvx

New preprint & OA dataset from the lab 🥳

An open dataset of cerebral tau deposition in young healthy adults based on [18F]MK6240 positron emission tomography

by Jack Lam and a terrific team of colleagues at the Neuro, Douglas and UCL

▶️ pdf doi.org/10.1101/2025...
▶️ bids osf.io/znt9d

⭐ preprint ⭐

In-vivo evidence for increased tau deposition in temporal lobe epilepsy

➡️ Using [¹⁸F]MK-6240 PET, we show increased tau in young and middle aged TLE
➡️ Tau aggregation potential mechanism of disease progression & cognitive decline
➡️ pdf bit.ly/4mmlTYH

by Raul Cruces & a super team

Preprint 🥳

"A unified imaging-histology framework for superficial white matter architecture studies in the human brain"

🧠 SMW key for brain structure-function links
🤔 understudied because of its complexity
💡 SMW mapping for histology & MRI
🌟 OA

📖 lnkd.in/ef8bGGrF

by Youngeun Hwang et al

in press @natcomms.nature.com 🌟

"Multimodal gradients unify local and global cortical organization"

7T MRI + cytoarchitectonics reveal a sensory-paralimbic axis of areal specialization & integration

led by superstar Yezhou Wang & a terrific team of friends & colleagues

▶️ doi.org/10.1038/s414...

Kudos to double doctor superstar @jroyer.bsky.social for defending her exemplary PhD research last week

🍾 Now in press @elife.bsky.social

Multimodal correlates of childhood psychopathology

co-led by @jroyer.bsky.social , Valeria Kebets, @bttyeo.bsky.social & our many fantastic co-authors

🙏 based on the ABCD dataset

👉 elifesciences.org/articles/87992

preprint up

Temporal lobe #epilepsy gradually perturbs cortex-wide excitation-inhibition balance

We combined connectomics, biophysical models, and EEG/cognitive phenotyping to identify mechanisms & consequences of E/I imbalance in TLE

By Ke Xie and a team of science superstars

bit.ly/EI-Epilepsy

🗓️ mark your calendars:

our gradients workshop 🧠🌈 is back on June 22 with an exciting speaker & session chair line up Sungkyunkwan University, one day before #OHBM
@ohbmtrainees.bsky.social

in Suwon, Korea info & registration (open soon) here: gradients-workshop.github.io

preprint 🧠 | "Connectome reorganization associated with temporal lobe pathology and its surgical resection" by Sara "The Rocket" Lariviere & a team superstar colleagues | on @medrxivpreprint.bsky.social because @biorxiv-neursci.bsky.social said it was too clinical for them 🥼 bit.ly/connectomeRe...

now in press @elife.bsky.social | "Evaluation of surface-based
hippocampal registration using ground-truth subfield definitions" by Jordan de Kraker, @neuroak.bsky.social & a fabulous team of hippocampus geeks 🍤🧲