Boris Louis 🧪🔬
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borislouis.bsky.social
Boris Louis 🧪🔬
@borislouis.bsky.social
Postdoc @KU Leuven | R&D | Chemists | Advanced optical imaging | Image processing and data analysis

Adventuring the microscopic and the real world !
Smartphone-based super resolution🔬

Microscopes are generally costly equipment, limiting availability in remote areas

Can we make a high-quality microscope cheaply?

This paper makes that vision more real
tinyurl.com/defxwzjf

With a cost below 350 euros, it delivers single-molecule sensitivity
October 20, 2025 at 10:08 AM
Microscopy building day 7-9
First images and final checks

We finally have a working microscope 🔬

After installing the camera, we tackled hardware software communications using @micro-manager.bsky.social

Then we performed usual checks:
1) fluorescent marker
2) scale bar
3) bead solution (PSF)
September 28, 2025 at 2:12 PM
How we analyze porous network @rochalab.bsky.social 🔬🧪

1) Adaptive thresholding
2)Distance map calculation
3)Watershed transformation
4)Quantification
5)3D rendering

Code : github.com/BorisLouis/S...

Paper: pubs.rsc.org/en/content/a...

#Microscopy #Optics #SciComm #ImageProcessing
May 15, 2025 at 7:50 AM
🧙‍♂️𝐋𝐨𝐫𝐝 𝐨𝐟 𝐭𝐡𝐞 𝐑𝐢𝐧𝐠𝐬: 𝐓𝐡𝐞 𝐓𝐰𝐨 𝐓𝐨𝐰𝐞𝐫𝐬 – 𝐌𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐞 𝐄𝐝𝐢𝐭𝐢𝐨𝐧 🔬 🧪

Meet our latest creation @hofkenslab.bsky.social and @rochalab.bsky.social labs:

A fully custom upright microscope built entirely from scratch, with no microscope body and no commercial frame.

#Optics #SciComm #Microscopy
May 5, 2025 at 8:09 AM
🔬Interested in imaging in energy science ?🔬

Chemical & Biomedical Imaging, a new journal from @acs.org, invited us for a special issue on

🔬𝐈𝐦𝐚𝐠𝐢𝐧𝐠 𝐢𝐧 𝐄𝐧𝐞𝐫𝐠𝐲 𝐬𝐜𝐢𝐞𝐧𝐜𝐞 ☀️ ⚡ 🧪

And we made the cover ! 🎊

Thanks to @alexeychizhik.bsky.social for the amazing design

#Microscopy #Optics #SciComm
May 1, 2025 at 9:08 AM
𝐋𝐨𝐨𝐤𝐢𝐧𝐠 𝐟𝐨𝐫𝐰𝐚𝐫𝐝 𝐭𝐨 𝐦𝐚𝐤𝐢𝐧𝐠 𝐜𝐨𝐧𝐧𝐞𝐜𝐭𝐢𝐨𝐧 𝐢𝐧 @spie.org 𝐎𝐩𝐭𝐢𝐜𝐬 + 𝐏𝐡𝐨𝐭𝐨𝐧𝐢𝐜𝐬 🔬 🧪

I’ve been invited to give a talk in San Diego (US) in August this year! 🔬

If you are attending, I would love to connect

arxiv.org/abs/2503.23839

#Microscopy #Optics #SciComm
April 30, 2025 at 7:51 AM
🔧 𝐁𝐮𝐢𝐥𝐝𝐢𝐧𝐠 𝐚 𝐧𝐞𝐰 𝐦𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐞 – 𝐃𝐚𝐲 #𝟐 🔬🧪

✅ First, we used the reference laser to project a perfect vertical line through the center of the objective holder. We marked a target on the ceiling for future alignments, an easy trick to save time later

#Optics #Microscopy #SciComm
April 24, 2025 at 9:18 AM
🔧 𝐓𝐡𝐢𝐬 𝐬𝐢𝐦𝐩𝐥𝐞 𝐭𝐨𝐨𝐥 𝐬𝐚𝐯𝐞𝐝 𝐦𝐞 𝐡𝐨𝐮𝐫𝐬 𝐝𝐮𝐫𝐢𝐧𝐠 𝐦𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐞 𝐛𝐮𝐢𝐥𝐝𝐢𝐧𝐠 🔬 🧪

How do you ensure the optics are aligned straight when building a microscope?

For lasers, I often use diaphragms, but again, how do you ensure they are at the exact same height and lateral position?
#Optics #Microscopy #SciComm
April 22, 2025 at 8:02 AM
🔬 𝐁𝐮𝐢𝐥𝐝𝐢𝐧𝐠 𝐨𝐟 𝐧𝐞𝐰 𝐦𝐢𝐜𝐫𝐨𝐬𝐜𝐨𝐩𝐞𝐬 – 𝐃𝐚𝐲 #𝟏 🔬
Exciting times in @rochalab.bsky.social and @hofkenslab.bsky.social Lab !🧪We're restarting to build microscopes, and I decided to guide two PhD students (Steven Huysecom and Toon Van Roy) through the process.
#Microscopy #optics #SciComm #sts
April 16, 2025 at 8:45 AM
First invited talk... and I missed my flight 😅✈️
What a wild 72h from 🇧🇪 to 🇸🇬!

Grateful to the organizers who reshuffled things so I could still speak — and even more shocked (and honored!) to get a prize for young speakers. 🔬🧪

Academia is a rollercoaster😅
Singapore, you were stunning 🌿💚
April 10, 2025 at 8:01 AM
🔬Unveiling charge carrier fate in Solar cell materials with CLIM2.0🔬🧪

Published in ACS Chemical & Biomedical Imaging (@pubs.acs.org,@acs.org)

💡Read more: pubs.acs.org/doi/10.1021/...

Collaboration: Tokyo tech & KU Leuven (@kuleuvenuniversity.bsky.social)
#Perovskites #SolarCells #imaging #optics
March 3, 2025 at 11:29 AM
Amazing week at Göttingen University in Prof. @joergenderlein.bsky.social Lab with Toon & @sudiptaseth.bsky.social !

🔬 We performed high-res imaging of optoelectronic materials & collected 200GB+ of data!

Thanks to Oleksii Nevskyi & @nradmacher.bsky.social for their help we’ll be back! 🚀
January 31, 2025 at 1:07 PM
🔬Transforming local intensity fluctuations in solar cells into information with CLIM🔬

Borrowing principles of AI and super-resolution optical microscopy, 𝐂𝐋𝐈𝐌 provide structural and functional information in photo-active materials.

Read more here: doi.org/10.1002/adma...

🧐 𝐁𝐮𝐭 𝐡𝐨𝐰 𝐝𝐨𝐞𝐬 𝐢𝐭 𝐰𝐨𝐫𝐤?
January 21, 2025 at 10:34 PM
The Correlation Clustering Imaging (CLIM) method developed with @sudiptaseth.bsky.social @hofkenslab.bsky.social, Scheblykin lab, had two milestones last week:
1) Science and innovation award (KU leuven)
2) Accepted in Advanced materials
You can read about it here, meanwhile: doi.org/10.26434/che...
December 9, 2024 at 2:24 PM
🔬 Nanoparticles flocking like birds!
Core-shell nanoparticles (200 nm gold, 100 nm silica) swarm under laser irradiation, mimicking flocking birds! 🐦 Rotate them by changing light polarization.

Learn more in our latest paper
@acspublications.bsky.social : pubs.acs.org/doi/10.1021/...
December 2, 2024 at 9:17 AM
✨ Great time at OPL 2024 in beautiful Valencia! ✨

Presented our work on Correlation Clustering Imaging (CLIM), exploring photophysics in perovskite solar cells. Chaired my 1st session, asking questions even outside my field, challenging!😅

Left with new ideas & contacts! First post on @bsky.app
November 28, 2024 at 9:01 PM