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blomgrengroup.bsky.social
@blomgrengroup.bsky.social
A research group at @karolinskainst.bsky.social focusing on long-term complications in paediatric brain tumour patients 🧠
Huge congratulations to @davidmenassa.bsky.social and all co-authors for developing and publishing DeepCellMap - a new algorithm allowing the spatial characterisation of microglia in health and disease! We are very proud to be a part of this fantastic work 🥳

www.nature.com/articles/s41...
Unraveling microglial spatial organization in the developing human brain with DeepCellMap, a deep learning approach coupled with spatial statistics - Nature Communications
DeepCellMap, a deep-learning tool, maps microglial organisation in the developing brain, revealing their spatial diversity, clustering patterns, and associations with blood vessels. DeepCellMap is ava...
www.nature.com
February 18, 2025 at 3:23 PM
Our single-cell study of medulloblastoma with our PhD student @yanaruchiy.bsky.social as a first author is now in print 🥳 Check it out!

academic.oup.com/noa/article/...
Genomic tumor evolution dictates human medulloblastoma progression
AbstractBackground. Medulloblastoma (MB) is the most common high-grade pediatric brain tumor, comprised of 4 main molecular subgroups—sonic-hedgehog (SHH),
academic.oup.com
December 20, 2024 at 3:41 PM
Check out our recent paper where we describe our newly developed method of isolating microglia and vascular cells for single-cell sequencing!

pubmed.ncbi.nlm.nih.gov/39211933/
Rapid and robust isolation of microglia and vascular cells from brain subregions for integrative single-cell analyses - PubMed
Cell isolation protocols from brain tissue include prolonged <i>ex vivo</i> processing durations, rendering them suboptimal for transcriptomic studies. Particularly for microglia and vascular cells, c...
pubmed.ncbi.nlm.nih.gov
November 27, 2024 at 4:19 PM