This project was brilliantly led by Sabrina Arif, and is a close collaboration with @fluca2406.bsky.social's lab, and the Global Microbiome Conservancy (Mathieu Groussin and Mathilde Poyet)

3. Specific microbes like Bifidobacterium adolescentis (influenced by dairy intake) directly affected metabolic gene expression.

2. High-diversity microbiomes elicited a stronger host transcriptional response, while low-diversity microbiomes triggered epithelial restructuring & glycolysis – a stress response that characterizes several chronic inflammatory diseases.

1. Urban microbiomes triggered stronger host immune responses, including TNF signaling and bacterial antigen recognition.

We used a cell culture-based experimental system, treating colonic epithelial cells with live gut microbiomes from rural and urban individuals from different populations (Ghana, Nigeria, Rwanda, Malaysia, US). We found super interesting results👇

The second BME UNITE Future Faculty Seminar will be on Monday, August 25th, at 1 pm EST. Come hear from Drs. Mattea Allert, Taj Yeruva, and Said Arévalo Alquichire, PhD to learn more about their science and future research programs! Register here: tinyurl.com/bmeunite25

That's great. But it's likely that this competition ended and funds were committed before their apparent shift in priorities

This is not just HHMI. All Chan Zuckerberg Initiative funding calls are CLOSED. The Gates Foundation has no Grand Challenges funding opportunities. I've never seen anything like this. Private foundations have just decided to stop supporting biomedical research.