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Reposted
Happy birthday to #LaskerLaureate Richard O. Hynes! He was recognized for his discoveries concerning integrins, which are key mediators of cell matrix and cell-cell adhesion in physiology and disease. 🧪
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Integrins—mediators of cell-matrix and cell-cell adhesion - Lasker Foundation
Explore All 2022 Winners & Awards > Richard O. Hynes Massachusetts Institute of Technology Erkki Ruoslahti Sanford Burnham Prebys Timothy A. Springer Boston Children’s Hospital/Harvard Medical School…
buff.ly
November 29, 2025 at 6:02 PM
Happy birthday to #LaskerLaureate Richard O. Hynes! He was recognized for his discoveries concerning integrins, which are key mediators of cell matrix and cell-cell adhesion in physiology and disease. 🧪
Read: buff.ly/metevu2
Watch: buff.ly/z4WQFA5
Read: buff.ly/metevu2
Watch: buff.ly/z4WQFA5
Reposted
This is how you get dead kids. Flu kills, COVID kills, vaccines protect. It's not that complicated. Trump admin would prefer people die so they can use the chaos to gain more power and money. That's it. 🩺 These men are ghouls and if they get their way, we will all be sicker and many more dead. 🧪
Vinay Prasad of the FDA claims that he has proof that 10 children died from COVID19 vaccines, so the FDA will now target flu shots, look at whether people should receive multiple vaccines at the same time, and make the vaccine approval process significantly more difficult.
FDA to impose strict new vaccine requirements, claiming child covid shot deaths
Vinay Prasad, the nation’s top vaccine regulator, said his team concluded that coronavirus shots were linked to children’s deaths, necessitating a new approach.
www.washingtonpost.com
November 29, 2025 at 3:13 PM
This is how you get dead kids. Flu kills, COVID kills, vaccines protect. It's not that complicated. Trump admin would prefer people die so they can use the chaos to gain more power and money. That's it. 🩺 These men are ghouls and if they get their way, we will all be sicker and many more dead. 🧪
Reposted
Pig-to-human decedent kidney xenotransplant achieved 61 days of stability and dialysis independence with alpha-Gal KO pig organs. No CD40 blockade used! PMID:41233546, Nature 2025, @Nature https://doi.org/10.1038/s41586-025-09847-6 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Physiology and immunology of pig-to-human decedent kidney xenotransplant | Nature
Xenotransplantation of genetically-modified pig kidneys offers a solution to the scarcity of organs for end-stage renal disease patients.1 We performed a 61-day alpha-Gal knock-out pig kidney and thymic autograft transplant into a nephrectomized brain-dead human using clinically approved immunosuppression, without CD40 blockade or additional genetic modification. Hemodynamic and electrolyte stability and dialysis independence were achieved. Post-operative day (POD) 10 biopsies revealed glomerular IgM and IgA deposition, activation of early complement components and mesangiolysis with stable renal function without proteinuria, a phenotype not seen in allotransplantation. On POD 33, an abrupt increase in serum creatinine was associated with antibody-mediated rejection and increased donor-specific IgG. Plasma exchange, C3/C3b inhibition and rabbit anti-thymocyte globulin (rATG), completely reversed xenograft rejection. Pre-existing donor-reactive T cell clones expanded progressively in th
doi.org
November 29, 2025 at 4:00 PM
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November 23, 2025 at 7:05 PM