Biointerphases
@bip-avs.bsky.social
A Journal of Biomaterials and Biological Interfaces
High-speed atomic force microscopy enabled direct visualization of single-molecule adsorption dynamics of bovine serum albumin and fibrinogen on silica nanoparticle coatings, revealing distinct, protein-specific and dynamic interfacial mechanisms.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Single-molecule dynamics of fibrinogen and bovine serum albumin adsorption on silica nanoparticle coatings observed using high-speed atomic force microscopy
High-speed atomic force microscopy (HS-AFM) was used to directly visualize the single-molecule adsorption dynamics of fibrinogen (FG) and bovine serum albumin (
doi.org
December 5, 2025 at 4:42 PM
High-speed atomic force microscopy enabled direct visualization of single-molecule adsorption dynamics of bovine serum albumin and fibrinogen on silica nanoparticle coatings, revealing distinct, protein-specific and dynamic interfacial mechanisms.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Soft probe particle tracking microrheology (S-PTM) tracks the motion of cell subcompartments to measure mechanical properties in the surrounding environment. In the nucleolus, S-PTM revealed distinct layers with different properties. doi.org/10.1116/6.00... @utbiomedical.bsky.social
Soft probe particle tracking microrheology using membraneless organelles to study viscoelasticity of nucleolar subcompartments
Tracking cellular viscoelastic properties is critical for identifying early signs of pathogenesis. We introduce soft probe particle tracking microrheology (S-PT
doi.org
December 3, 2025 at 7:18 PM
Soft probe particle tracking microrheology (S-PTM) tracks the motion of cell subcompartments to measure mechanical properties in the surrounding environment. In the nucleolus, S-PTM revealed distinct layers with different properties. doi.org/10.1116/6.00... @utbiomedical.bsky.social
On our latest cover, we feature research from @iitbengaluru.bsky.social studying the role of the proteoglycan Decorin in regulating ovarian cancer progression. Glycosaminoglycan chains in Decorin are crucial to its role fighting invasive cells. 💪
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
November 20, 2025 at 7:22 PM
On our latest cover, we feature research from @iitbengaluru.bsky.social studying the role of the proteoglycan Decorin in regulating ovarian cancer progression. Glycosaminoglycan chains in Decorin are crucial to its role fighting invasive cells. 💪
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
In evaluating peptide binding against an Au(111) surface, this group from IIT Gandhinagar used molecular dynamics simulations to compare solid-binding peptides for biosensing, while showing the limitations of phage display techniques.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Promiscuous binding peptides—Computational screening reveals higher-affinity peptides for gold binding beyond phage display selections
Peptides that selectively bind to inorganic surfaces play a crucial role in nanobiotechnology, biomaterials, and biosensing applications. While phage display ha
doi.org
November 17, 2025 at 8:11 PM
In evaluating peptide binding against an Au(111) surface, this group from IIT Gandhinagar used molecular dynamics simulations to compare solid-binding peptides for biosensing, while showing the limitations of phage display techniques.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Cellulose scaffolds made from decellularized pacific dulse seaweed have inflammatory/antimicrobial properties & compatibility with cardiac cells, showing the promise of seaweed-derived cellulose in tissue engineering & other biomedical applications.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Development and optimization of decellularized seaweed scaffolds for tissue engineering
In this study, the marine red seaweed Devaleraea mollis (commonly known as Pacific dulse) was investigated as a green, sustainable, and animal-free tissue scaff
doi.org
November 12, 2025 at 6:40 PM
Cellulose scaffolds made from decellularized pacific dulse seaweed have inflammatory/antimicrobial properties & compatibility with cardiac cells, showing the promise of seaweed-derived cellulose in tissue engineering & other biomedical applications.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Using urea as a denaturing agent, authors from IIT Kanpur show that the proteolysis rate of human serum albumin (HSA) with papain is dependent on conformational state, with HSA digestion accelerating at unfolded states.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Dissecting the role of substrate folding in enzymatic digestion
The efficiency of enzymatic proteolysis is often attributed to the properties of the enzyme itself, with the substrate typically viewed as a passive participant
doi.org
November 10, 2025 at 8:37 PM
Using urea as a denaturing agent, authors from IIT Kanpur show that the proteolysis rate of human serum albumin (HSA) with papain is dependent on conformational state, with HSA digestion accelerating at unfolded states.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
To temper adverse uterine side effects from copper IUD implantation, researchers created a biomimetic microstructure inspired by golden pothos leaves using femtosecond laser texturing. This could effectively mitigate copper-ion burst release. doi.org/10.1116/6.00...
Femtosecond laser-textured copper surface for reducing initial copper ion burst release in intrauterine devices
Copper intrauterine devices (Cu-IUDs) are widely used for long-term contraception; yet, the burst release of Cu2+ during early implantation often induces advers
doi.org
October 28, 2025 at 7:23 PM
To temper adverse uterine side effects from copper IUD implantation, researchers created a biomimetic microstructure inspired by golden pothos leaves using femtosecond laser texturing. This could effectively mitigate copper-ion burst release. doi.org/10.1116/6.00...
Our latest cover features an article from @uarkansas.bsky.social on the relationship between bacterial motility and soil microstructures and how it impacts nutrient cycling, bioremediation, and overall soil health.
Article: doi.org/10.1116/6.00...
Issue: pubs.aip.org/avs/bip/issu...
Article: doi.org/10.1116/6.00...
Issue: pubs.aip.org/avs/bip/issu...
September 10, 2025 at 5:52 PM
Our latest cover features an article from @uarkansas.bsky.social on the relationship between bacterial motility and soil microstructures and how it impacts nutrient cycling, bioremediation, and overall soil health.
Article: doi.org/10.1116/6.00...
Issue: pubs.aip.org/avs/bip/issu...
Article: doi.org/10.1116/6.00...
Issue: pubs.aip.org/avs/bip/issu...
This review from Zhejiang University systematically summarizes the pharmacological properties of terpenoids, alkaloids, flavonoids, polysaccharides & other components & explores integration with biomaterials such as nanoparticle delivery systems, microneedles, & hydrogels.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Emerging biomedical applications of herbal extracts-based biomaterials
Bioactive herbal extracts have garnered significant attention due to their multitarget regulation and low toxicity, yet their clinical applications are limited
doi.org
September 5, 2025 at 4:32 PM
This review from Zhejiang University systematically summarizes the pharmacological properties of terpenoids, alkaloids, flavonoids, polysaccharides & other components & explores integration with biomaterials such as nanoparticle delivery systems, microneedles, & hydrogels.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Researchers from @iitdelhi.bsky.social use two forms of graphene to demonstrate how material surface potential affects protein behavior.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Surface potential modulates fibronectin adsorption and molecular interaction on graphene-based materials
Protein interactions on graphene-based materials (GBMs) are predominantly governed by interphase surface properties such as surface chemistry and roughness; how
doi.org
July 25, 2025 at 4:39 PM
Researchers from @iitdelhi.bsky.social use two forms of graphene to demonstrate how material surface potential affects protein behavior.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Featured on our most recent cover, researchers from Dalian University of Technology used bioinformatics & machine learning approaches to reveal the involvement of necroptosis-related genes and altered immune infiltration in hepatoblastoma pathogenesis.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
July 22, 2025 at 6:38 PM
Featured on our most recent cover, researchers from Dalian University of Technology used bioinformatics & machine learning approaches to reveal the involvement of necroptosis-related genes and altered immune infiltration in hepatoblastoma pathogenesis.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
How do E. coli & other motile bacteria move through wet soil? This study out of @uarkansas.bsky.social explores how soil particle structures affect bacterial behavior—key for understanding nutrient cycling, soil health, & ecosystem dynamics. doi.org/10.1116/6.00...
Bacterial motility in aqueous micro-environment with natural soil particles
Bacterial motility is essential for navigating heterogeneous environments like soil, where it plays a key role in nutrient cycling, bioremediation, and overall
doi.org
July 10, 2025 at 6:56 PM
How do E. coli & other motile bacteria move through wet soil? This study out of @uarkansas.bsky.social explores how soil particle structures affect bacterial behavior—key for understanding nutrient cycling, soil health, & ecosystem dynamics. doi.org/10.1116/6.00...
Researchers from Thapar Institute of Engineering & Technology developed a targeted magnetic drug delivery system using PEG-coated iron oxide nanoparticles loaded with doxorubicin & tagged with luteinizing hormone-releasing hormone (Triptorelin) for lung & breast cancer cells.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
In vitro assessment of polyethylene glycol-coated iron oxide nanoparticles integrating luteinizing hormone releasing-hormone targeted magnetic hyperthermia and doxorubicin for lung and breast cancer c...
Magnetic nanoparticle-based targeted hyperthermia, combined with chemotherapy, is a promising approach for cancer treatment. In this study, a targeted magnetic
doi.org
June 11, 2025 at 1:06 PM
Researchers from Thapar Institute of Engineering & Technology developed a targeted magnetic drug delivery system using PEG-coated iron oxide nanoparticles loaded with doxorubicin & tagged with luteinizing hormone-releasing hormone (Triptorelin) for lung & breast cancer cells.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Accounting for 10-25% of facial fractures, orbital fractures cause complications which are exacerbated when the fracture is not repaired properly. This review covers the pros & cons of commonly-used implants & explores the future of implant development. doi.org/10.1116/6.00...
Advances in materials research related to orbital reconstruction: A review
Orbital injuries or defects caused by various reasons are quite common, such as violent trauma or tumors. If the damaged orbits are not treated in a timely mann
doi.org
June 4, 2025 at 1:20 PM
Accounting for 10-25% of facial fractures, orbital fractures cause complications which are exacerbated when the fracture is not repaired properly. This review covers the pros & cons of commonly-used implants & explores the future of implant development. doi.org/10.1116/6.00...
🚨Calling all researchers in China!🚨
This collection focuses on the current progress of biointerface science in China - and we want YOUR perspective! Submit until August 30, 2025.
tinyurl.com/4yux6jrj
This collection focuses on the current progress of biointerface science in China - and we want YOUR perspective! Submit until August 30, 2025.
tinyurl.com/4yux6jrj
Biointerfaces in China | Biointerphases Special Topic Collections
Email from AVS Call for Research Articles Special Topic Collection: Biointerfaces in China Manuscript Deadline: August 30, 2025 Biointerphases is soliciting articles for publication in a Special To
tinyurl.com
May 29, 2025 at 6:03 PM
🚨Calling all researchers in China!🚨
This collection focuses on the current progress of biointerface science in China - and we want YOUR perspective! Submit until August 30, 2025.
tinyurl.com/4yux6jrj
This collection focuses on the current progress of biointerface science in China - and we want YOUR perspective! Submit until August 30, 2025.
tinyurl.com/4yux6jrj
🚨New cover just dropped!🚨
In the featured study, authors at @KyushuUniv_EN explore enhancing epithelial tissue sealing of dental implants made from materials like Ti–6Al–4V, which exhibits superior tensile strength & hardness compared to pure titanium.
doi.org/10.1116/6.00...
In the featured study, authors at @KyushuUniv_EN explore enhancing epithelial tissue sealing of dental implants made from materials like Ti–6Al–4V, which exhibits superior tensile strength & hardness compared to pure titanium.
doi.org/10.1116/6.00...
May 21, 2025 at 5:08 PM
🚨New cover just dropped!🚨
In the featured study, authors at @KyushuUniv_EN explore enhancing epithelial tissue sealing of dental implants made from materials like Ti–6Al–4V, which exhibits superior tensile strength & hardness compared to pure titanium.
doi.org/10.1116/6.00...
In the featured study, authors at @KyushuUniv_EN explore enhancing epithelial tissue sealing of dental implants made from materials like Ti–6Al–4V, which exhibits superior tensile strength & hardness compared to pure titanium.
doi.org/10.1116/6.00...
This Tutorial from @umich.edu reviews early & future studies on peptides/proteins at interfaces, highlighting the evolution of #sumfrequencygeneration into a powerful tool for probing interfacial structures, orientation, & interactions.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Early sum frequency generation vibrational spectroscopic studies on peptides and proteins at interfaces
This paper summarizes the early research results on studying proteins and peptides at interfaces using sum frequency generation (SFG) vibrational spectroscopy.
doi.org
May 12, 2025 at 2:23 PM
This Tutorial from @umich.edu reviews early & future studies on peptides/proteins at interfaces, highlighting the evolution of #sumfrequencygeneration into a powerful tool for probing interfacial structures, orientation, & interactions.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
This tutorial describes an electronic SFG experimental setup to probe electronic states present at interfaces, and provides instrumental and experimental details for those wishing to begin or optimize an ESFG setup for themselves.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Development of electronic sum frequency generation spectrophotometer to assess the buried interfaces
The interfacial region between two bulk media in organic semiconductor based devices, such as organic field-effect transistors (OFETs), organic light-emitting d
doi.org
May 7, 2025 at 6:00 PM
This tutorial describes an electronic SFG experimental setup to probe electronic states present at interfaces, and provides instrumental and experimental details for those wishing to begin or optimize an ESFG setup for themselves.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Too reactive, not reactive enough, or just right? Precisely engineered surfaces can ensure proper cell adhesion & function. Submit your research concerning phenomena such as this to our collection on The Goldilocks Principle!
tinyurl.com/4kn5b54a
tinyurl.com/4kn5b54a
The Goldilocks Principle in Biomaterials and Biointerfaces - AIP Publishing LLC
tinyurl.com
May 5, 2025 at 4:25 PM
Too reactive, not reactive enough, or just right? Precisely engineered surfaces can ensure proper cell adhesion & function. Submit your research concerning phenomena such as this to our collection on The Goldilocks Principle!
tinyurl.com/4kn5b54a
tinyurl.com/4kn5b54a
ToF-SIMS is capable of very high spatial resolution while producing enormous amounts of information about surface composition. This review from @latrobeuni.bsky.social explores algorithms that have been applied to ToF-SIMS images over the past few decades.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Applications of multivariate analysis and unsupervised machine learning to ToF-SIMS images of organic, bioorganic, and biological systems
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) imaging offers a powerful, label-free method for exploring organic, bioorganic, and biological systems
doi.org
May 1, 2025 at 2:11 PM
ToF-SIMS is capable of very high spatial resolution while producing enormous amounts of information about surface composition. This review from @latrobeuni.bsky.social explores algorithms that have been applied to ToF-SIMS images over the past few decades.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Surface-modified cement with polyacrylamide (PAM) or PAM/chitosan enhances biofilm & #coralgrowth while maintaining strength, showing promise for eco-friendly #coastalengineering. Long-term durability and biocompatibility tests will be needed.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Phenomenological investigation of organic modified cements as biocompatible substrates interfacing model marine organisms
Organic modification can generally endow inorganic materials with novel and promotional characteristics to fit into new functionalities. In this paper, new ceme
doi.org
April 28, 2025 at 7:51 PM
Surface-modified cement with polyacrylamide (PAM) or PAM/chitosan enhances biofilm & #coralgrowth while maintaining strength, showing promise for eco-friendly #coastalengineering. Long-term durability and biocompatibility tests will be needed.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Our most-read review article, this work discusses advances in drug-eluting contact lenses: preparation, drug-loading & ocular penetration strategies, release mechanisms, drug delivery & penetration detection, safety, & biocompatibility validation methods.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Drug-eluting contact lenses: Progress, challenges, and prospects
Topical ophthalmic solutions (eye drops) are becoming increasingly popular in treating and preventing ocular diseases for their safety, noninvasiveness, and eas
doi.org
April 24, 2025 at 3:01 PM
Our most-read review article, this work discusses advances in drug-eluting contact lenses: preparation, drug-loading & ocular penetration strategies, release mechanisms, drug delivery & penetration detection, safety, & biocompatibility validation methods.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Researchers from Kyushu University show how hydrothermal CaCl₂ treatment of Ti64 #implants boosts laminin-332 & cell attachment, enhancing soft tissue sealing & implant stability without changing surface topography. @avs-members.bsky.social
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Enhancing epithelial tissue sealing of titanium alloy implants through CaCl2-based hydrothermal treatment
The long-term stability of dental implants is significantly influenced by their resistance to foreign factors in the peri-implant epithelium (PIE). Despite this
doi.org
April 21, 2025 at 6:38 PM
Researchers from Kyushu University show how hydrothermal CaCl₂ treatment of Ti64 #implants boosts laminin-332 & cell attachment, enhancing soft tissue sealing & implant stability without changing surface topography. @avs-members.bsky.social
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Welcome to our new Associate Editor, @brookefarrugia.bsky.social from University of Melbourne! We look forward to working with her as she continues to contribute to BIP and @avs-members.bsky.social.
tinyurl.com/cmaa4byn
tinyurl.com/cmaa4byn
Brooke Farrugia Appointed BIP Associate Editor
Email from AVS Dr. Brooke Farrugia Appointed New Biointerphases Associate Editor Dr. Brooke Farrugia is an Associate Professor in the Department of Biomedical Engineering at the University of Melbo
tinyurl.com
April 17, 2025 at 5:11 PM
Welcome to our new Associate Editor, @brookefarrugia.bsky.social from University of Melbourne! We look forward to working with her as she continues to contribute to BIP and @avs-members.bsky.social.
tinyurl.com/cmaa4byn
tinyurl.com/cmaa4byn
To address the proliferation of microbes in textiles used in public health areas, researchers integrated specific ratios of #antimicrobial agents (IPBC, ZPT, OIT) into nylon, finding some produce additive effects without reducing whiteness or strength.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...
Enhanced bactericidal performance of textiles through compound antimicrobial agents
This study aims to explore the essential functional requirements associated with controlling the proliferation of microbes in the domain of textiles used in pub
doi.org
April 14, 2025 at 4:43 PM
To address the proliferation of microbes in textiles used in public health areas, researchers integrated specific ratios of #antimicrobial agents (IPBC, ZPT, OIT) into nylon, finding some produce additive effects without reducing whiteness or strength.
doi.org/10.1116/6.00...
doi.org/10.1116/6.00...