CryoEM Alsace
@bios-me-alsace.bsky.social
Structural Biology Electron Microscopy Plateform @IGBMC | FRISBI INSTRUCT-ERIC CENTER Strasbourg
Another achievement , published last year in @science.org ! @valeroche.bsky.social lab @igbmc.bsky.social, and collaborators @ibensens.bsky.social @bcmfromthelabs.bsky.social solved the first structure of E.coli DNA gyrase recognizing a DNA cross-over, using #streptavidin affinity grids !
October 14, 2025 at 11:22 AM
Another achievement , published last year in @science.org ! @valeroche.bsky.social lab @igbmc.bsky.social, and collaborators @ibensens.bsky.social @bcmfromthelabs.bsky.social solved the first structure of E.coli DNA gyrase recognizing a DNA cross-over, using #streptavidin affinity grids !
We are pleased to highlight this article published by @gruberlab.bsky.social. At DCI, F. Roisne Hamelin and collaborators used electron microscopy — and in particular our streptavidin affinity grids — to reveal the mechanism by which Wadjet binds to the plasmid to initiate loop extrusion.
How do SMC complexes load onto DNA to get ready for loop extrusion?
@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸♂️🤸♂️🤸♂️.
Check out the new paper: www.cell.com/molecular-ce...
@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸♂️🤸♂️🤸♂️.
Check out the new paper: www.cell.com/molecular-ce...
October 14, 2025 at 5:48 AM
We are pleased to highlight this article published by @gruberlab.bsky.social. At DCI, F. Roisne Hamelin and collaborators used electron microscopy — and in particular our streptavidin affinity grids — to reveal the mechanism by which Wadjet binds to the plasmid to initiate loop extrusion.
New preprint: Using #CryoEM, our #Streptavidin grids @IGBMC, and MD-simulations,@FabioLapenta and co-workers solved near atomic structure of the human Major Vault Protein and analysed its dynamics !
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
October 14, 2025 at 5:44 AM
New preprint: Using #CryoEM, our #Streptavidin grids @IGBMC, and MD-simulations,@FabioLapenta and co-workers solved near atomic structure of the human Major Vault Protein and analysed its dynamics !
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...