TK (Takashi DY) Kozai
@bioniclab.bsky.social
Ernest E Roth Professor. Dept Bioengineering, University of Pittsburgh.
BionicLab.org
Neural Engineering; Neural Interfaces: Neurostimulation; Neurocomputation
BionicLab.org
Neural Engineering; Neural Interfaces: Neurostimulation; Neurocomputation
New from University of Pittsburgh Neural Engineering Cross-Translation (UP NExT): PV interneurons don’t just control brain rhythms, they fine-tune blood flow too.
2P imaging + optogenetics, we found depth-specific vasoconstriction & dilation shaping both sensory-evoked & resting-state hemodynamics.
2P imaging + optogenetics, we found depth-specific vasoconstriction & dilation shaping both sensory-evoked & resting-state hemodynamics.
November 10, 2025 at 12:41 AM
New from University of Pittsburgh Neural Engineering Cross-Translation (UP NExT): PV interneurons don’t just control brain rhythms, they fine-tune blood flow too.
2P imaging + optogenetics, we found depth-specific vasoconstriction & dilation shaping both sensory-evoked & resting-state hemodynamics.
2P imaging + optogenetics, we found depth-specific vasoconstriction & dilation shaping both sensory-evoked & resting-state hemodynamics.
Small movements between the brain and the array create stress on tissue differently:
-Outer electrodes: Take the most direct mechanical stress, causing scarring.
-Inner electrodes: Stress on the edges can pinch blood vessels, reducing nutrients to neurons in the center, weakening them over time.
-Outer electrodes: Take the most direct mechanical stress, causing scarring.
-Inner electrodes: Stress on the edges can pinch blood vessels, reducing nutrients to neurons in the center, weakening them over time.
November 6, 2025 at 1:20 AM
Small movements between the brain and the array create stress on tissue differently:
-Outer electrodes: Take the most direct mechanical stress, causing scarring.
-Inner electrodes: Stress on the edges can pinch blood vessels, reducing nutrients to neurons in the center, weakening them over time.
-Outer electrodes: Take the most direct mechanical stress, causing scarring.
-Inner electrodes: Stress on the edges can pinch blood vessels, reducing nutrients to neurons in the center, weakening them over time.
Strong showing from @PittBioE’s UP NExT program at #SfN2025 in San Diego!
Trainees & faculty are advancing neural engineering across scales, from glial modulation & ICMS to neurovascular imaging & computational models.
See how Pitt is redefining neural engineering.
#Neurotech
Trainees & faculty are advancing neural engineering across scales, from glial modulation & ICMS to neurovascular imaging & computational models.
See how Pitt is redefining neural engineering.
#Neurotech
October 23, 2025 at 3:45 PM
Strong showing from @PittBioE’s UP NExT program at #SfN2025 in San Diego!
Trainees & faculty are advancing neural engineering across scales, from glial modulation & ICMS to neurovascular imaging & computational models.
See how Pitt is redefining neural engineering.
#Neurotech
Trainees & faculty are advancing neural engineering across scales, from glial modulation & ICMS to neurovascular imaging & computational models.
See how Pitt is redefining neural engineering.
#Neurotech
Exciting new opportunity at the University of Pittsburgh Neural Engineering Cross-Translation (UP NExT) program
@mcapo.bsky.social
@mcapo.bsky.social
October 18, 2025 at 11:17 AM
Exciting new opportunity at the University of Pittsburgh Neural Engineering Cross-Translation (UP NExT) program
@mcapo.bsky.social
@mcapo.bsky.social
August 23, 2025 at 11:48 PM
Golden fuses K-pop precision + Western pop structure. Like integrative scientists, hybrid talent drives breakthroughs. Reward synthesis, don’t punish it. #NIH #NSF #Innovation #Multidisciplinarity
August 23, 2025 at 11:48 PM
Golden fuses K-pop precision + Western pop structure. Like integrative scientists, hybrid talent drives breakthroughs. Reward synthesis, don’t punish it. #NIH #NSF #Innovation #Multidisciplinarity
Thrilled to be promoted to full professor! Grateful to my students, colleagues, & peers in review. Your challenges & support sharpened our science for impact. What a 10-yr journey it's been since starting my lab in 2015! #AcademicTwitter #Science
August 5, 2025 at 12:54 PM
Thrilled to be promoted to full professor! Grateful to my students, colleagues, & peers in review. Your challenges & support sharpened our science for impact. What a 10-yr journey it's been since starting my lab in 2015! #AcademicTwitter #Science
Maximizing taxpayer-funded research means capping journal fees, but we must avoid delays & support early-career scientists. Share ideas for equitable, cost-effective publishing with NIH by 9/15/25: osp.od.nih.gov/comment-form... #OpenAccess #SciencePolicy #NIH
July 31, 2025 at 2:30 AM
Maximizing taxpayer-funded research means capping journal fees, but we must avoid delays & support early-career scientists. Share ideas for equitable, cost-effective publishing with NIH by 9/15/25: osp.od.nih.gov/comment-form... #OpenAccess #SciencePolicy #NIH
PATRIOTS! The Senate’s NIH vote on 7/31 could lock in a disastrous multi-year funding policy, slashing $7B from research. It KILLS jobs in PA, AL, WV, WASTES your tax dollars, hikes healthcare costs, & lets China win in science. #SaveNIH #AmericaFirst
July 28, 2025 at 4:25 PM
PATRIOTS! The Senate’s NIH vote on 7/31 could lock in a disastrous multi-year funding policy, slashing $7B from research. It KILLS jobs in PA, AL, WV, WASTES your tax dollars, hikes healthcare costs, & lets China win in science. #SaveNIH #AmericaFirst
🚨 NIH’s 2025 policy pushing non-animal methods for grants risks harming neuroscience & taxpayers. Organoids can’t mimic brain implant or vision systems. White Coat Waste’s pressure & Project 2025’s cuts add urgency. Comment by 7/14, 5 PM EST
#NIH #Project2025 #Neuroscience #FDA #BCI #NeuroTech
#NIH #Project2025 #Neuroscience #FDA #BCI #NeuroTech
July 12, 2025 at 3:46 PM
🚨 NIH’s 2025 policy pushing non-animal methods for grants risks harming neuroscience & taxpayers. Organoids can’t mimic brain implant or vision systems. White Coat Waste’s pressure & Project 2025’s cuts add urgency. Comment by 7/14, 5 PM EST
#NIH #Project2025 #Neuroscience #FDA #BCI #NeuroTech
#NIH #Project2025 #Neuroscience #FDA #BCI #NeuroTech
Axolotl mucus could fight MRSA & cancer, per a PLOS ONE study: done w/o funding. NIH’s shift from basic research to translational “wins” leaves breakthroughs to chance. Basic science, like CRISPR’s roots, needs funding to deliver taxpayer value. #ScienceFunding #Innovation #NIH #BasicScience
July 10, 2025 at 2:35 PM
Axolotl mucus could fight MRSA & cancer, per a PLOS ONE study: done w/o funding. NIH’s shift from basic research to translational “wins” leaves breakthroughs to chance. Basic science, like CRISPR’s roots, needs funding to deliver taxpayer value. #ScienceFunding #Innovation #NIH #BasicScience
NIH’s 2025 policy on animal testing grants worries neuroscientists. Organoids & in silico models can’t yet replicate glymphatic systems for brain implants or complex vision circuits. Strict animal model justifications may delay funding & discoveries. #Neuroscience #NIH
July 8, 2025 at 2:50 PM
NIH’s 2025 policy on animal testing grants worries neuroscientists. Organoids & in silico models can’t yet replicate glymphatic systems for brain implants or complex vision circuits. Strict animal model justifications may delay funding & discoveries. #Neuroscience #NIH
OBBBA's $5T deficit, Medicaid/SNAP cuts, & AI deregulation spark backlash. Unpopular (24 pts underwater), it risks alienating MAGA's base with higher prices & job threats, hurting GOP in '26 midterms. #BigBeautifulBill
June 29, 2025 at 11:16 PM
OBBBA's $5T deficit, Medicaid/SNAP cuts, & AI deregulation spark backlash. Unpopular (24 pts underwater), it risks alienating MAGA's base with higher prices & job threats, hurting GOP in '26 midterms. #BigBeautifulBill
June 12, 2025 at 1:23 AM
DOGE experiment has cost US taxpayers >$34B to find out fraud was "relatively non-existent", says DOGE engineer. (DOGE operational cost, administrative leave, lost productivity, buyout, severance package, rehiring packages, on-boarding time)
June 7, 2025 at 1:37 PM
DOGE experiment has cost US taxpayers >$34B to find out fraud was "relatively non-existent", says DOGE engineer. (DOGE operational cost, administrative leave, lost productivity, buyout, severance package, rehiring packages, on-boarding time)
Thank you speakers and attendees for amazing talks and discussions.
May 20, 2025 at 8:37 PM
Thank you speakers and attendees for amazing talks and discussions.
Looking forward to these amazing speakers: stim.bioniclab.org/schedule
May 19, 2025 at 1:52 PM
Looking forward to these amazing speakers: stim.bioniclab.org/schedule
Congratulations Dr. Kevin Stieger!
March 22, 2025 at 8:51 PM
Congratulations Dr. Kevin Stieger!
Remember Executive Order 9066 (aka Order 66)
March 16, 2025 at 2:47 PM
Remember Executive Order 9066 (aka Order 66)
Join us for the University of Pittsburgh's Neuroscience / Neural Engineering Workshop on May 19-20th! This event brings together leading experimental & computational neuroscientists to drive progress in cross-species, reverse & forward translation of cortical circuits & behavior.
stim.bioniclab.org
stim.bioniclab.org
March 3, 2025 at 4:57 PM
Join us for the University of Pittsburgh's Neuroscience / Neural Engineering Workshop on May 19-20th! This event brings together leading experimental & computational neuroscientists to drive progress in cross-species, reverse & forward translation of cortical circuits & behavior.
stim.bioniclab.org
stim.bioniclab.org
Probationary doesn't mean underperformers. It also means outstanding performers that got a promotion, and if that promotion "failed" during the probationary period, then they would return to the pre-promotion position. Instead, DOGE just fired everyone.
February 17, 2025 at 3:36 AM
Probationary doesn't mean underperformers. It also means outstanding performers that got a promotion, and if that promotion "failed" during the probationary period, then they would return to the pre-promotion position. Instead, DOGE just fired everyone.
The chaos is real. www.bbc.com/news/article...
FFS, call your senators, house representative (work & home address), governor, AG 2x/day.
Tell them recent events threaten your safety, health, and economy.
FFS, call your senators, house representative (work & home address), governor, AG 2x/day.
Tell them recent events threaten your safety, health, and economy.
February 16, 2025 at 4:07 PM
The chaos is real. www.bbc.com/news/article...
FFS, call your senators, house representative (work & home address), governor, AG 2x/day.
Tell them recent events threaten your safety, health, and economy.
FFS, call your senators, house representative (work & home address), governor, AG 2x/day.
Tell them recent events threaten your safety, health, and economy.
Many NIH staff work beyond regular hours without overtime pay—not for personal gain, but because they are deeply committed to advancing science and serving the taxpayers. Their dedication drives medical breakthroughs that benefit us all. #ScienceMatters #PublicService
February 14, 2025 at 2:28 PM
Many NIH staff work beyond regular hours without overtime pay—not for personal gain, but because they are deeply committed to advancing science and serving the taxpayers. Their dedication drives medical breakthroughs that benefit us all. #ScienceMatters #PublicService