Dimitrije
@biodimi.bsky.social
I read, write and edit DNA
Postoc at @geochurch.bsky.social lab (current), PhD with @marcguellc.bsky.social (past)
Postoc at @geochurch.bsky.social lab (current), PhD with @marcguellc.bsky.social (past)
This work has been possible thanks to an incredible team effort w/ Alejandro, @marcguellc.bsky.social @noeliaferruz.bsky.social and the integra therapeutics team!
October 2, 2025 at 6:11 PM
This work has been possible thanks to an incredible team effort w/ Alejandro, @marcguellc.bsky.social @noeliaferruz.bsky.social and the integra therapeutics team!
The improved variants are compatible with therapeutic T cell editing and Cas9-guided programmable integration. We also observed domain acquisitions in parts of the HyPB phylogeny. Stay tuned for future work on improving gene writing systems.🧬❇️
October 2, 2025 at 6:10 PM
The improved variants are compatible with therapeutic T cell editing and Cas9-guided programmable integration. We also observed domain acquisitions in parts of the HyPB phylogeny. Stay tuned for future work on improving gene writing systems.🧬❇️
We explored and experimentally tested the natural diversity of PiggyBac transposases. We then used protein language models to enhance the efficiency of the current best PiggyBac transposase, Hyperactive PiggyBac.
October 2, 2025 at 6:10 PM
We explored and experimentally tested the natural diversity of PiggyBac transposases. We then used protein language models to enhance the efficiency of the current best PiggyBac transposase, Hyperactive PiggyBac.