BIO Integration
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BIO Integration
@bio-integration.org
Advancing multidisciplinary biomedical research.
Open Access • CiteScore 3.3 • No article processing charges.
https://bio-integration.org/
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BIOI achieves a #CiteScore of 3.3!

We gratefully acknowledge the contributions made by our editors, reviewers and readers and the authors for choosing us!

Yet another reason to publish in BIOI!

#OpenAccess: bio-integration.org
This review highlights the transformative potential of combining ultrasound and microneedles for enhanced transdermal drug delivery (TDD). @usf.edu

#OpenAccess: bio-integration.org/ultrasound-m...
Combined Ultrasound and Microneedle for Enhanced Transdermal Delivery: Synergistic Mechanisms and Therapeutic Advances
Announcing a new article publication for BIO Integration journal. Transdermal drug delivery (TDD) offers a non-invasive alternative to conventional administration routes, yet the efficacy of TDD is co...
bio-integration.org
November 20, 2025 at 1:25 PM
This study presents a brain–spinal interface that translates human motion intentions to restore leg movements, offering hope for paralysis rehabilitation. #EpiduralElectricalStimulation #SpinalCordInjury

#OpenAccess: bio-integration.org/brainspinal-...
WukongBot: A Brain-Spine Interface Proof of Concept Based on Non-Invasive Brain-Computer Interface for Spinal Cord Injury in a Monkey
Announcing a new article publication for BIO Integration journal. Motor dysfunction constitutes a significant global public health burden. In China, greater than 20 million individuals have various fo...
bio-integration.org
November 13, 2025 at 11:04 AM
Summarizing the recent material innovation, structural designs, & energy integration technology breakthroughs in wearable #FlexibleSensors with a discussion on their applications in #MotionMonitoring, challenges, & future directions.

#OpenAccess: bio-integration.org/wearablesens...
Recent Advances and Future Prospects in Wearable Flexible Sensors for Motion Monitoring
Announcing a new article publication for BIO Integration journal.  In recent years, substantial advancements have been made in the field of wearable flexible sensors. These sensors possess elasticity ...
bio-integration.org
October 28, 2025 at 9:51 AM
Reviewing the feasibility of cell membrane-derived #nanovesicles as #nanoprobes in #MultimodalImaging, current challenges limiting its applications & future directions for developing high-precision imaging strategies.

#OpenAccess: bio-integration.org/nanoprobes-n...
Harnessing Cell Membrane-Derived Nanovesicles for Enhanced Nanoprobes in Multimodal Imaging: Progress and Perspectives
Announcing a new article publication for BIO Integration journal. Cell membrane-derived nanovesicles (CMNVs) are natural nanocarriers efficiently encapsulating bioactive molecules and imaging probes. ...
bio-integration.org
October 28, 2025 at 7:47 AM
This review highlights #ExtracellularVesicles as biocompatible carriers that transport #biomolecules, mediate intercellular communication & hold promise for diagnostics, #RegenerativeMedicine, highlights #biomedical potential, translational challenges #OpenAccess: bio-integration.org/extracellula...
Exogenous Extracellular Vesicles as Emerging Platforms in Translational Medicine
Announcing a new article publication for BIO Integration journal. Extracellular vesicles (EVs) are nanoscale, membrane-bound carriers that are naturally secreted by cells and capable of transporting p...
bio-integration.org
September 25, 2025 at 1:11 PM
This commentary evaluates PATCH, a light/ultrasound-activated #nanozyme that repurposes proximity labeling to create dense synthetic #antigen clusters on #tumor cells, boosting T-cell activation & durable antitumor immunity.

#OpenAccess: bio-integration.org/antigen-ampl...
A Strategy for Antigen Amplification via Nanozyme-Catalyzed Proximity Labeling
Announcing a new article publication for BIO Integration journal. This article discusses a new therapeutic strategy called PATCH (Proximity Antigen Tagging of Cytotoxic Haptens), which adapts proximit...
bio-integration.org
September 18, 2025 at 12:06 PM
This commentary delves into the translational potential of UV photofunctionalization in orthopaedic implants & outlines the key mechanisms & applications which represents a novel, additive-free, deployable method that improves osseointegration. #openaccess: bio-integration.org/uvphotofunct...
Role of Photofunctionalization in Orthopedic Customized Implants
Announcing a new article publication for BIO Integration journal. Ultraviolet (UV) photofunctionalization is a promising surface activation strategy for orthopedic implants that offers a safe, coating...
bio-integration.org
September 17, 2025 at 7:53 AM
This commentary underscores collagen’s active role in #tumor growth, #immune evasion, and #therapy resistance, defining ‘armored & cold’ tumors as #collagen-rich, immune-poor #cancers outlining novel therapeutic strategies to overcome these barriers.
#OpenAccess: bio-integration.org/collagen-the...
Armored and Cold Tumors: A Refractory Subset of Solid Cancer
Announcing a new article publication for BIO Integration journal. Solid tumors are characterized by extensive extracellular matrix (ECM) remodeling prominently featuring massive collagen deposition. T...
bio-integration.org
September 17, 2025 at 7:34 AM
Analysis of the complex interactions between DEGs, immune-related genes, and music & exercise therapy-associated genes in Alzheimer’s disease (AD), identified #IL2RB & #TUBA1B as potential therapeutic targets in AD. @fudan-university.bsky.social

#OpenAccess: bio-integration.org/degs-musicth...
IL2RB and TUBA1B are Potential Targets of Music Therapy for Alzheimer’s Disease and Cognitive Impairment
Announcing a new article publication for BIO Integration journal. This study examined the complex interactions among differential gene expression, immune responses, therapy-associated genes in Alzheim...
bio-integration.org
September 4, 2025 at 8:57 AM
Discussing the neuroprotective role of quercetin, its mechanism of action & pharmacological efficacy, with a discussion on the implications of translating quercetin-based therapies into precision neurotherapeutics for the treatment of neurodegenerative diseases.

bio-integration.org/neuroprotect...
Mechanistic Insights and Therapeutic Potential of Quercetin in Neuroprotection: A Comprehensive Review of Pathways and Clinical Perspectives
Announcing a new article publication for BIO Integration journal.  Quercetin, a bioactive flavonoid abundant in diverse plant species, has been extensively investigated for its neuroprotective propert...
bio-integration.org
August 20, 2025 at 1:59 PM
This review summarizes the role of LIPUS in tissue regeneration, explores strategies to accelerate clinical adoption of LIPUS and provides a roadmap for advancing LIPUS-driven regenerative medicine in the era of precision bioengineering. @csu.edu.au

#OpenAccess: bio-integration.org/low-intensit...
Mechanoregulation of Cell Fate by Low-intensity Pulsed Ultrasound: Mechanisms and Advances in Regenerative Medicine
Announcing a new article publication for BIO Integration journal. As a mechanical wave capable of transmitting thermal and mechanical energy, ultrasound has emerged as a pivotal tool in regenerative m...
bio-integration.org
August 1, 2025 at 2:55 PM
An overview of the current advances in drug delivery systems in osteochondral tissue regeneration, with discussion on the feasibility of various biomaterials-based drug delivery system in osteochondral tissue regeneration. @ucl.ac.uk

Open Access: bio-integration.org/drug-deliver...
Advances in Drug Delivery Systems for Osteochondral Tissue Regeneration
Announcing a new article publication for BIO Integration journal. Osteochondral damage is primarily caused by degeneration of articular cartilage due to trauma, degenerative injury. Current approaches...
bio-integration.org
August 1, 2025 at 2:06 PM
This editorial-commentary discusses about Articulate Medical Intelligence Explorer (AMIE), a new #AI system that outperforms #doctors in diagnostic accuracy, empathy, and dialogue in a recent Nature study —paving the way for AI-assisted care.
#OpenAccess: bio-integration.org/articulate-m...
Conversational AI in Medicine: Redefining Diagnostics with AMIE
Announcing a new article publication for BIO Integration journal exploring the groundbreaking potential of Articulate Medical Intelligence Explorer (AMIE), a large language model (LLM)-driven conversa...
bio-integration.org
July 30, 2025 at 9:59 AM
This study investigates the feasibility of using extended tight-binding (xTB) methods integrated with end-point free energy calculations to evaluate receptor-ligand binding and shows that xTB methods are advantageous in challenging cases.

#OpenAccess: bio-integration.org/endpointscre...
Multiscale End-point Screening with Extended Tight-binding Hamiltonians
Announcing a new article publication for BIO Integration journal. Extended tight-binding (xTB) methods offer a computationally efficient alternative to classical force fields and ab initio quantum met...
bio-integration.org
July 25, 2025 at 9:39 AM
This study reports that low-intensity pulsed ultrasound irradiation (LIPUS) enhances the anti-tumor efficacy of natural killer (NK) cells, against ovarian cancer, by modulating the activating the Wnt/β-catenin signaling pathway.

#OpenAccess: bio-integration.org/lipus-nkcell...
Low-intensity Pulsed Ultrasound Enhances NK Cell Adoptive Therapy by Modulating the Wnt/β-catenin Signaling Pathway
Announcing a new article publication for BIO Integration journal. Natural killer cell adoptive therapy is a novel immunotherapy strategy for the treatment of multiple refractory tumors, including ovar...
bio-integration.org
July 17, 2025 at 10:35 AM
This study demonstrates significant differences in #intestinalflora structures and metabolite abundance between #chemotherapy-sensitive and #drugresistant patients, thereby offering potential #biomarkers for the formulation of #personalizedtreatment strategies.

bio-integration.org/intestinal-m...
Effects of the Intestinal Microbiome and Metabolites on Neoadjuvant Chemotherapy Efficacy in Breast Cancer
Announcing a new article publication for BIO Integration journal. Imbalances in the intestinal microbiome are closely associated with the occurrence and development of cancer, and can affect tumorigen...
bio-integration.org
July 14, 2025 at 1:56 PM
This review explores asymmetric cell division (ACD) in tissue homeostasis, #cancer initiation, progression, therapeutic resistance, and #metastasis, and describes the mechanisms regulating ACD in #glioblastoma progression & therapy outcomes.

#OpenAccess: bio-integration.org/acd-cancer-l...
Asymmetric Cell Division as a Mechanistic Contributor to Cancer with a Focus on Glioblastoma
Announcing a new article publication for BIO Integration journal. Asymmetric cell division (ACD) has a crucial role in normal cellular differentiation and tissue homeostasis. The mechanisms underlying...
bio-integration.org
July 9, 2025 at 11:58 AM
5-Flurouracil-loaded chitin #nanohydrogel exhibits enhanced #DrugRelease and high cytotoxicity against #SkinCancer cells, highlighting its potential as a promising topical delivery agent in the treatment of skin cancer.

#OpenAccess: bio-integration.org/chitin-nanoh...
Anticancer Efficacy of 5-Fluorouracil-Loaded Chitin Nanohydrogel in Enhanced Skin Cancer Therapy
Announcing a new article publication for BIO Integration journal. The pyrimidine analog 5-flurouracil (5-FU) is effective against solid tumors. However, the half-life of intravenously administered 5-F...
bio-integration.org
July 9, 2025 at 11:51 AM
This commentary summarizes the mechanistic functions of microRNA-223 (#miR223) in #HepaticStellateCell activation and #fibrosis, discusses its #therapeuticpotential and highlights it as a complex but intriguing target for #antifibrotic treatment.

#OpenAccess: bio-integration.org/micrornas-li...
MicroRNAs in Liver Fibrosis: Unraveling Intercellular Crosstalk and the Regulatory Functions of MicroRNA-223
Announcing a new article publication for BIO Integration journal. Liver fibrosis is caused by excessive extracellular matrix accumulation, which in turn is driven by activation of hepatic stellate cel...
bio-integration.org
July 9, 2025 at 11:44 AM
A comprehensive summary on how music therapy #CognitiveFunction, language expression, and motor function in #stroke patients with a discussion on various challenges that hinder its successful clinical application. #StrokeRehabilitation

#OpenAccess: bio-integration.org/application-...
Application of Music Therapy in Stroke Rehabilitation: A Research Review
Announcing a new article publication for BIO Integration journal. This article provides a systematic review of music therapy research progress and clinical applications in stroke rehabilitation. Music...
bio-integration.org
July 4, 2025 at 2:40 PM
BIOI achieves a #CiteScore of 3.3!

We gratefully acknowledge the contributions made by our editors, reviewers and readers and the authors for choosing us!

Yet another reason to publish in BIOI!

#OpenAccess: bio-integration.org
June 19, 2025 at 6:36 AM
This recent review provides an overview of #antibioticresistance in #Mycobacterium spp. with a focus on several key factors, such as enzyme-mediated antibiotic deactivation, gene expression, #biofilm formation, and the role of #effluxpumps.

#OpenAccess: bio-integration.org/combating-mu...
Combating Multi-drug Resistant Mycobacterium Species by Efflux Pump Inhibitors: Contemporary Trends
Announcing a new article publication for BIO Integration journal. Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M.tb) complex (MTBC), which includes M.tb as one of the causative bacteria....
bio-integration.org
June 4, 2025 at 10:19 AM
A new study uncovers lysine vitcylation as a novel anti-tumor mechanism of Vitamin C. This commentary explores its impact on Tumor Treatment and future clinical applications. #TumorTreatment #VitaminC #Cancer therapy #Immuneactivation #Lysine vitcylation

bio-integration.org/vitamin-cyla...
Vitcylation of Lysine: The Novel Mechanism of Vitamin C in Tumor Treatment
Announcing a new article publication for BIO Integration journal. Vitamin C, an essential nutrient for human health, has critical roles in numerous biological processes. Vitamin C’s potential in disea...
bio-integration.org
May 29, 2025 at 9:29 AM
Bridging Disciplines, Empowering Innovation: BIOI Forum Highlights | Held at the 14th Westlake International Conference of Ultrasound in Medicine and Biology, May 8 - May 11, 2025, Hangzhou, China.

Learn more: bio-integration.org/bridging-dis...

#InnovationInScience #FutureOfBiotech #BioTechTrends
Bridging Disciplines, Empowering Innovation: BIOI Forum Highlights
Held at the 14th Westlake International Conference of Ultrasound in Medicine and Biology May 8 – May 11, 2025, Hangzhou, China As part of the 14th Westlake International Conference on Ultrasound in Me...
bio-integration.org
May 19, 2025 at 10:05 AM
Breakthroughs in diabetes treatment! Explore how receptors like KATP, GLUT4, and PPAR-γ are targeted by new drugs and natural compounds from 2020–2024. A new era in glucose control!

www.scienceopen.com/hosted-docum...

#biguanides #DM #DPP4 #GLUT4 #PPARγ #SGLT2 #sulfonylureas
Recent Developments in Diabetes Management: Exploring Receptors, Pathways, and Compounds
<p xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" class="first" dir="auto" id="d24020e141">Diabetes mellitus (DM) is a widespread metabolic disorder with profound effects on vital o...
www.scienceopen.com
May 9, 2025 at 10:14 AM