Bjarke Feenstra
@bfeenstra.bsky.social
Genetic epidemiology, statistical genetics. #pregnancy #febrile seizures #pyloric stenosis. Group leader at Statens Serum Institut, Copenhagen. Views are my own.
Interesting. Seems to connect well with the IL-1 locus we found in a fetal GWAS of gestational duration www.nature.com/articles/s41...
Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration - Nature Communications
Gestational duration depends on both maternal and fetal genetic influences. Here, the authors perform a fetal genome-wide association meta-analysis and find that a locus on 2q13 is associated with pre...
www.nature.com
August 17, 2025 at 6:54 PM
Interesting. Seems to connect well with the IL-1 locus we found in a fetal GWAS of gestational duration www.nature.com/articles/s41...
More details at our group website: feenstralab.github.io/posts/2025-0...
FeenstraLab: PhD project - genetics, fetal growth, pregnancy ultrasound images
PhD fellowship in the genetics of fetal and placental growth measures derived from pregnancy ultrasound images
feenstralab.github.io
June 27, 2025 at 3:55 PM
More details at our group website: feenstralab.github.io/posts/2025-0...
GWAS summary statistics available here: www.danishnationalbiobank.com/gwas
/fin
/fin
GWAS summary data tables
In an effort to further research and collaboration, GWAS summary data has been made available here.
www.danishnationalbiobank.com
March 23, 2025 at 4:40 PM
GWAS summary statistics available here: www.danishnationalbiobank.com/gwas
/fin
/fin
31 genome-wide significant loci were found, harbouring plausible candidate genes like NFAT5, SAMD9, and SLC4A10. Intriguingly, MAGMA analysis showed enrichment of expression in pituitary tissue, underlining the importance of this gland in systemic osmolality regulation.
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March 23, 2025 at 4:38 PM
31 genome-wide significant loci were found, harbouring plausible candidate genes like NFAT5, SAMD9, and SLC4A10. Intriguingly, MAGMA analysis showed enrichment of expression in pituitary tissue, underlining the importance of this gland in systemic osmolality regulation.
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Despite the power of these resources, we found no genetic associations for TIH. However, we also conducted GWAS analysis of plasma sodium in general, combining our results with a previous GWAS meta-analysis and detected many signals.
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March 23, 2025 at 4:26 PM
Despite the power of these resources, we found no genetic associations for TIH. However, we also conducted GWAS analysis of plasma sodium in general, combining our results with a previous GWAS meta-analysis and detected many signals.
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We made use of (1) nationwide Danish registers for repeated sodium measurements and filled prescriptions of thiazides, and (2) Danish Blood Donor study and Copenhagen Hospital Biobank cohorts with existing genetic data for about half a million participants.
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March 23, 2025 at 4:19 PM
We made use of (1) nationwide Danish registers for repeated sodium measurements and filled prescriptions of thiazides, and (2) Danish Blood Donor study and Copenhagen Hospital Biobank cohorts with existing genetic data for about half a million participants.
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Heavy lifting by Frank Geller in strong collaboration with Danish Blood Donor Study, Copenhagen Hospital Biobank, FinnGen, @estbiobank.bsky.social , Mass General Brigham Biobank, Statens Serum Institut.
November 22, 2024 at 3:06 PM
Heavy lifting by Frank Geller in strong collaboration with Danish Blood Donor Study, Copenhagen Hospital Biobank, FinnGen, @estbiobank.bsky.social , Mass General Brigham Biobank, Statens Serum Institut.