Jan Beumer, PharmD PhD DABT
@beumercancer.bsky.social
Pharmacology and drug development at Johns Hopkins University
As usual, nuance and understanding the context is important… I’ve seen some good examples of the importance of studying both sexes… but the policy has been interpreted rather strictly
February 25, 2025 at 3:51 PM
As usual, nuance and understanding the context is important… I’ve seen some good examples of the importance of studying both sexes… but the policy has been interpreted rather strictly
Often it is due to sex differences in drug metabolism in rodents, which do not replicate in humans. So the blanket duplication of experiments may needlessly increase animal use, or worse (if mixing male and female animals) will increase within-group variability and diminish statistical power.
February 25, 2025 at 3:49 PM
Often it is due to sex differences in drug metabolism in rodents, which do not replicate in humans. So the blanket duplication of experiments may needlessly increase animal use, or worse (if mixing male and female animals) will increase within-group variability and diminish statistical power.
And then return the change due
February 12, 2025 at 9:01 PM
And then return the change due
Wasn’t the snow asbestos?
February 12, 2025 at 8:58 PM
Wasn’t the snow asbestos?