Michael Betts
@bettsupenn.bsky.social
Professor of Microbiology at the University of Pennsylvania, expert in human immunology.
Our latest research preprint demonstrating chemokine- based targeting of mRNA-LNPs to cytotoxic CD8 T cells and NK cells. A first in class gene therapy strategy. www.biorxiv.org/content/10.1...
In vivo reprogramming of cytotoxic effector CD8+ T cells via fractalkine-conjugated mRNA-LNP
Selective in vivo reprogramming of cytotoxic effector CD8+ T (Teff) cells holds tremendous promise as a therapeutic tool but has not yet been accomplished. Here, we demonstrate that fractalkine-conjug...
www.biorxiv.org
October 31, 2025 at 1:05 AM
Our latest research preprint demonstrating chemokine- based targeting of mRNA-LNPs to cytotoxic CD8 T cells and NK cells. A first in class gene therapy strategy. www.biorxiv.org/content/10.1...