The Berro lab
@berrolab.bsky.social
Mechanobiology, actin, endocytosis @Yale
Reposted by The Berro lab
Here is NIGMS.
This reflects Jon Lorsch's push away from R01s and toward MIRA awards (R35s). While there are some advantages to the R35 mechanism, there are downsides to "putting all of your eggs in one basket" as some discovered this year.
8/n
This reflects Jon Lorsch's push away from R01s and toward MIRA awards (R35s). While there are some advantages to the R35 mechanism, there are downsides to "putting all of your eggs in one basket" as some discovered this year.
8/n
October 1, 2025 at 4:08 PM
Here is NIGMS.
This reflects Jon Lorsch's push away from R01s and toward MIRA awards (R35s). While there are some advantages to the R35 mechanism, there are downsides to "putting all of your eggs in one basket" as some discovered this year.
8/n
This reflects Jon Lorsch's push away from R01s and toward MIRA awards (R35s). While there are some advantages to the R35 mechanism, there are downsides to "putting all of your eggs in one basket" as some discovered this year.
8/n
Don’t hesitate to get in touch if you want to use them in your favorite protein, we’re happy to help!
January 20, 2025 at 9:45 PM
Don’t hesitate to get in touch if you want to use them in your favorite protein, we’re happy to help!
… and, at last, a few grants! We’re recruiting synthetic biologists and cell engineers! DM me for more details
January 20, 2025 at 9:44 PM
… and, at last, a few grants! We’re recruiting synthetic biologists and cell engineers! DM me for more details
It already led to cool discoveries, a pending patent, [the start of] a startup… (doi.org/10.1016/j.celrep.2024.114725; doi.org/10.1126/sciadv.adi1535; patents.google.com/patent/WO2024006993A1)
Redirecting
doi.org
January 20, 2025 at 9:44 PM
It already led to cool discoveries, a pending patent, [the start of] a startup… (doi.org/10.1016/j.celrep.2024.114725; doi.org/10.1126/sciadv.adi1535; patents.google.com/patent/WO2024006993A1)
Despite countless rejected grant applications, tireless efforts of super postdoc (and soon to be faculty) Yuan Ren, in collaboration with Jie Yang from Yongli Zhang’s lab, and many collaborators, made the magic happen!
January 20, 2025 at 9:44 PM
Despite countless rejected grant applications, tireless efforts of super postdoc (and soon to be faculty) Yuan Ren, in collaboration with Jie Yang from Yongli Zhang’s lab, and many collaborators, made the magic happen!
This work was incepted around the time I started my lab in 2013, inspired by previous work from Yongli Zhang’s lab.
January 20, 2025 at 9:43 PM
This work was incepted around the time I started my lab in 2013, inspired by previous work from Yongli Zhang’s lab.
Since our sensors do not use a FRET reporter, they are very small and can be inserted in virtually any protein without disrupting its function. We and collaborators have inserted them in 20+ proteins in fungi, nematodes and mammals, with ~90% success!
January 20, 2025 at 9:43 PM
Since our sensors do not use a FRET reporter, they are very small and can be inserted in virtually any protein without disrupting its function. We and collaborators have inserted them in 20+ proteins in fungi, nematodes and mammals, with ~90% success!