Benjamin Schwabe
benschwabe.bsky.social
Benjamin Schwabe
@benschwabe.bsky.social
(Bio)chemistry PhD student @ Uni of York, UK
Reposted by Benjamin Schwabe
We all assumed nicotine biosynthesis was long elucidated, didn't we? :)
Well, it wasn't but now it is thanks to this work led by @benschwabe.bsky.social @lichmanlab.bsky.social
Learned about these results last summer, a pleasure to see the preprint out, congratulations!
#natprod
#PlantScience
Nicotine biosynthesis completed by cryptic activating glucosylation https://www.biorxiv.org/content/10.64898/2025.12.04.692101v1
December 7, 2025 at 1:35 PM
Reposted by Benjamin Schwabe
The centuries old mystery of how tobacco plants make nicotine has a sweet solution: an additional glucose group is vital for the key pathway steps. Read more in our pre-print: www.biorxiv.org/content/10.6.... Incredible work from @benschwabe.bsky.social and collaborators in York and Copenhagen.
Nicotine biosynthesis completed by cryptic activating glucosylation
Nicotine is a neuroactive alkaloid produced by tobacco (Nicotiana tabacum) as a defense against herbivory, and an addictive stimulant that has been used by humans for millennia. Despite its significan...
www.biorxiv.org
December 8, 2025 at 9:19 AM
Reposted by Benjamin Schwabe
Nicotine biosynthesis completed by cryptic activating glucosylation https://www.biorxiv.org/content/10.64898/2025.12.04.692101v1
December 7, 2025 at 1:45 AM