Ben Auerbach
@benauerbach.bsky.social
ML scientist at Calico Life Sciences | Building DNA language models
Reposted by Ben Auerbach
⚡️ Our latest preprint is on bioRxiv!
Shift augmentation improves DNA convolutional neural network indel effect predictions
www.biorxiv.org/content/10.1...
Shift augmentation improves DNA convolutional neural network indel effect predictions
www.biorxiv.org/content/10.1...
Shift augmentation improves DNA convolutional neural network indel effect predictions
Determining genetic variant effects on molecular phenotypes like gene expression is a task of paramount importance to medical genetics. DNA convolutional neural networks (CNNs) attain state-of-the-art...
www.biorxiv.org
April 16, 2025 at 9:13 PM
⚡️ Our latest preprint is on bioRxiv!
Shift augmentation improves DNA convolutional neural network indel effect predictions
www.biorxiv.org/content/10.1...
Shift augmentation improves DNA convolutional neural network indel effect predictions
www.biorxiv.org/content/10.1...
Reposted by Ben Auerbach
Congrats to Johannes Linder, David Kelley et al. on the journal publication of Borzoi - a long context sequence models of RNA-seq coverage profiles with many nice applications for transcriptional & post-transcriptional regulation & variant effect prediction.
www.nature.com/articles/s41... 1/
www.nature.com/articles/s41... 1/
Predicting RNA-seq coverage from DNA sequence as a unifying model of gene regulation - Nature Genetics
Borzoi adapts the Enformer sequence-to-expression model to directly predict RNA-seq coverage, enabling the in-silico analysis of variant effects across multiple layers of gene regulation.
www.nature.com
January 8, 2025 at 10:06 PM
Congrats to Johannes Linder, David Kelley et al. on the journal publication of Borzoi - a long context sequence models of RNA-seq coverage profiles with many nice applications for transcriptional & post-transcriptional regulation & variant effect prediction.
www.nature.com/articles/s41... 1/
www.nature.com/articles/s41... 1/