Beatriz Pinheiro Soares
@beatrizpsoares.bsky.social
PhD student at Karin de Visser group at NKI
MSCA Adaptmet Doctoral Network fellowship
MSCA Adaptmet Doctoral Network fellowship
Reposted by Beatriz Pinheiro Soares
Hi Bluesky community:)
Our new manuscript is now available as a preprint!⛅️
biorxiv.org/content/10.1...
1/ Here, we describe a novel BMAL1-YAP complex in epidermal cells, which is hijacked during ageing to control the expression of up-regulated inflammation genes through enhancer binding.🧵
Our new manuscript is now available as a preprint!⛅️
biorxiv.org/content/10.1...
1/ Here, we describe a novel BMAL1-YAP complex in epidermal cells, which is hijacked during ageing to control the expression of up-regulated inflammation genes through enhancer binding.🧵
BMAL1 and YAP cooperate to hijack enhancers and promote inflammation in the aged epidermis
Ageing is characterised by persistent low-grade inflammation that is linked to impaired tissue homeostasis and functionality. However, the molecular mechanisms driving age-associated inflammation rema...
biorxiv.org
April 23, 2025 at 2:49 PM
Hi Bluesky community:)
Our new manuscript is now available as a preprint!⛅️
biorxiv.org/content/10.1...
1/ Here, we describe a novel BMAL1-YAP complex in epidermal cells, which is hijacked during ageing to control the expression of up-regulated inflammation genes through enhancer binding.🧵
Our new manuscript is now available as a preprint!⛅️
biorxiv.org/content/10.1...
1/ Here, we describe a novel BMAL1-YAP complex in epidermal cells, which is hijacked during ageing to control the expression of up-regulated inflammation genes through enhancer binding.🧵