Beatrice Borsari
beaborsari.bsky.social
Beatrice Borsari
@beaborsari.bsky.social
Postdoc @Yale
Reposted by Beatrice Borsari
New @natcomms.nature.com ‬ paper led by @beaborsari.bsky.social ‬ & Mor Frank. Also thanks to co-authors Eve Wattenberg, @xuke0828.bsky.social , Susanna Liu, Xuezhu Yu & @markgerstein.bsky.social
August 25, 2025 at 3:38 PM
Reposted by Beatrice Borsari
Curious how your favorite gene changes when and how during a biological process?
Want to dive into the kinetics of chromatin + gene expression?
Meet chronODE, our new tool to model multi-omic time-series with logistic equations + ML!
doi.org/10.1038/s414...
The chronODE framework for modelling multi-omic time series with ordinary differential equations and machine learning - Nature Communications
Here, the authors use a simple equation to study how genes and their regulators switch on/off over time, across the whole genome in tissues and cells. Most changes are gradual, but some genes switch q...
doi.org
August 25, 2025 at 3:37 PM