Michael Baym
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baym.lol
Michael Baym
@baym.lol
Associate Prof @HarvardMed. Microbial evolution, antibiotic resistance, mobile genetic elements, algorithms, phages, molecular biotech, etc. Basic research is the engine of progress.

baymlab.hms.harvard.edu
You’re writing ✨speculative science fiction✨
November 23, 2025 at 12:23 AM
Reposted by Michael Baym
Which we were able to show experimentally by competing plasmids in a displacement assay. We see plasmids that contain an IS605 have an enormous advantage over those that don’t, despite the IS itself being detrimental to plasmid replication
November 20, 2025 at 10:12 PM
I look forward to it, my friend
November 21, 2025 at 9:20 PM
Thank you, that truly means a lot to me
November 21, 2025 at 9:06 PM
Thank you again!
November 21, 2025 at 6:15 PM
What a coincidence 😉
November 21, 2025 at 5:32 PM
Fernando is truly one of the most brilliant scientists I’ve ever met
November 21, 2025 at 4:05 PM
Omg thank you so so much
November 21, 2025 at 4:05 PM
Dense… yeah… the original draft was like 30-40% over the length limit
November 21, 2025 at 3:49 PM
Thank you so so much!
November 21, 2025 at 3:48 PM
Jfc
November 21, 2025 at 12:21 PM
Thank you!
November 21, 2025 at 2:28 AM
Very cool!
November 21, 2025 at 12:51 AM
This was the one from S. eubayanus. (H/t @maitreya.bsky.social) We found it had the same FRT site and no activity at 37, very little at 35, and essentially full at 30.
November 21, 2025 at 12:40 AM
Reposted by Michael Baym
I almost forgot
November 20, 2025 at 10:13 PM
Reposted by Michael Baym
This work highlights how interactions between MGEs can produce unique effects where both benefit from their nested existence. Furthermore, we have extended TnpB’s mechanism that sheds light on why TnpB is so successful.
November 20, 2025 at 10:12 PM